Aprogen Cefaclor Dry Syrup 125 mg/5 mL

Adult dose

As cefaclor, administer 250 mg (potency) once every 8 hours orally. For severe infections (like pneumonia) and infections with low susceptibility, the dose can be doubled. For acute gonococcal urethritis, a single dose of this medication 3 g with probenecid 1 g should be administered.

Child dose

Administer 20 mg (potency) per kg body weight divided every 8 hours. For severe infections, otitis media, and infections with low susceptibility, 40 mg (potency) per kg body weight may be administered daily, with a maximum dose of.

This medication works by binding to specific proteins and inhibiting bacterial cell wall synthesis, which kills bacteria. It should not be used in patients who have had severe allergic reactions or shock from this medication or similar antibiotics in the past. Patients with a history of allergy to penicillin antibiotics or those who are prone to allergic reactions such as asthma, rashes, or hives should use this medication with caution. Patients with very poor kidney function, those unable to take oral medications, elderly patients, or those in poor general health should be closely monitored for signs of vitamin K deficiency. Care should be taken when administering to patients with a history of gastrointestinal diseases, especially colitis. This medication can rarely cause severe allergic reactions, skin disorders, blood abnormalities, liver or kidney dysfunction, gastrointestinal problems, or neurological issues, so any symptoms should be communicated to a physician promptly. To prevent the development of resistant bacteria, it is important to check the sensitivity of the infecting bacteria and administer the medication only for the necessary duration. Caution is required when combining with other medications as it may affect kidney function, especially when used with anticoagulants or diuretics where careful monitoring of blood coagulation status is necessary. When taken with oral contraceptives, the contraceptive effect may be reduced, so using additional contraception is advisable. The safety of this medication during pregnancy or breastfeeding has not been fully established, and it should only be used cautiously when absolutely necessary. Nursing mothers should observe the infant's condition carefully. This medication is not recommended for use in infants under one month of age as its safety and efficacy have not been established. Elderly patients may have a higher incidence of adverse reactions due to decreased body function, so dosage and administration intervals should be adjusted and used with caution. During the use of this medication, it is important to inform healthcare personnel of its use as it may affect the results of certain clinical tests.

Serious side effects

• Urticaria
• edema
• dyspnea
• shock
• Stevens-Johnson syndrome
• toxic epidermal necrolysis
• jaundice
• acute renal failure
• interstitial pneumonia
• eosinophilic lung infiltration

Mild side effects

• Generalized flushing
• vascular edema
• sensory disturbances
• syncope
• hypertension
• vasodilation
• rash
• erythema
• itching
• fever

This medication is sensitive to light and should be stored in an opaque container. It should be kept at room temperature, away from extreme heat or cold.

Appearance

This medication is a pink syrup with a strawberry flavor that is reconstituted before use.

Package unit

150 mL/bottle