Medication info
Aprogen Cefaclor Capsule 250 Milligrams

Aprogen Cefaclor Capsule 250 Milligrams

Prescription medicationHard capsule경구
Ingredient · strength
Cefaclor Hydrate›250mg / 1 capsule
Manufacturer / importer
(주)에이프로젠바이오로직스
Appearance
A hard capsule with a blue upper part and a white lower part filled with a pale yellow powder.
Packaging
30, 300 capsules/bottle
Approval status
Active

MFDS item code 199701105 · Notified 1997.05.20 · Insurance code 645201370

Summary

Main use
Treatment of respiratory and urinary tract infections such as otitis media and pneumonia
Who takes it
Adults · Children
Adult dose
Administer 250mg (potency) of cefaclor hydrate by oral route every 8 hours. For severe infections (such as pneumonia) and infections with low susceptibility, the dose may be increased to double. In cases of acute gonococcal urethritis, administer this medication 3g combined with 1g of probenecid as a single dose.
Child dose
Administer 20mg (potency) per kg body weight per day divided into doses every 8 hours. In cases of severe infections, otitis media, and infections with low susceptibility, a dose of 40mg (potency) per kg body weight per day may be administered, with a maximum dosage of 1g (potency) per day.

Ingredients

Manufacturer
(주)에이프로젠바이오로직스

Efficacy & effects

Treatment of respiratory and urinary tract infections such as otitis media and pneumonia

  • Otitis media
  • pneumonia
  • pharyngitis
  • tonsillitis
  • bronchitis
  • pyelonephritis
  • cystitis
  • gonococcal urethritis
  • boils
  • abscesses
  • folliculitis
  • soft tissue infections
View approved original text

This medication is effective against various types of bacteria including Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus. The main indications include respiratory diseases such as otitis media, pneumonia, pharyngitis, tonsillitis, and bronchitis. It is also used for urinary infections such as pyelonephritis, cystitis, and gonococcal urethritis. This drug is effective in treating skin infections such as boils, abscesses, folliculitis, soft tissue infections, infectious granulomas, subcutaneous abscesses, neglectful wounds, and wound infections. This medication is broadly used for treating various diseases caused by different bacterial infections.

How to take

Adult dose

Administer 250mg (potency) of cefaclor hydrate by oral route every 8 hours. For severe infections (such as pneumonia) and infections with low susceptibility, the dose may be increased to double. In cases of acute gonococcal urethritis, administer this medication 3g combined with 1g of probenecid as a single dose.

Child dose

Administer 20mg (potency) per kg body weight per day divided into doses every 8 hours. In cases of severe infections, otitis media, and infections with low susceptibility, a dose of 40mg (potency) per kg body weight per day may be administered, with a maximum dosage of 1g (potency) per day.

Precautions

This medication works by binding to specific proteins and disrupting bacterial cell wall synthesis, leading to bacterial death. Before using this medication, it is important to inform if there have been any prior severe allergic reactions or shock to this drug or similar antibiotics. Caution should be exercised if there is a history of allergies to penicillin antibiotics or a tendency to show allergic symptoms such as asthma, rash, or hives. Patients with severely impaired kidney function, those who have difficulty swallowing, elderly patients, or those in poor general condition are at risk of bleeding due to vitamin K deficiency and should be observed carefully. Individuals with past gastrointestinal diseases, particularly those with a history of colitis, must inform their doctor immediately if symptoms like abdominal pain or diarrhea occur while taking this medication. This drug may cause various side effects, including severe allergic reactions, skin rashes, blood disorders, liver or kidney dysfunctions, severe colitis, and neurological symptoms; if any unusual symptoms arise, immediate consultation with a healthcare provider is necessary. If symptoms such as shortness of breath, widespread rash, severe vomiting or diarrhea, or changes in consciousness occur during treatment, the drug should be stopped immediately, and appropriate treatment should be sought. To reduce the occurrence of resistant bacteria, it is important to perform susceptibility testing and take this medication only for the necessary duration. This medication may interact with other drugs, so it is essential to inform healthcare providers about any currently taken medications. Women who are pregnant or breastfeeding should consider the benefits and risks carefully if this medication is needed, and during breastfeeding, closely monitor any effects on the baby. Safety has not been established for infants under 1 month of age, so it is advisable not to use it in this age group. Elderly patients may experience side effects more easily due to decreased bodily functions and should use the medication with careful adjustments to dosage and intervals.

Side effects and when to seek care immediately

Serious side effects

  • Hives
  • severe swelling (edema)
  • shortness of breath
  • difficulty in breathing
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
  • liver dysfunction (jaundice)
  • acute renal failure
  • severe colitis
  • seizures
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  • severe allergic reactions
  • severe neurological symptoms.

Mild side effects

  • General flushing
  • vascular swelling
  • sensory abnormalities
  • fainting
  • hypertension
  • vasodilation
  • rash
  • itching
  • fever
  • lymph node enlargement
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  • joint pain
  • serum sickness-like reactions
  • agranulocytosis
  • granulocytopenia
  • pancytopenia
  • anemia
  • thrombocytopenia
  • eosinophilia
  • lymphocytosis
  • leukopenia
  • aplastic anemia
  • hemolytic anemia
  • reversible neutropenia
  • temporary hepatitis
  • elevated AST
  • elevated ALT
  • elevated ALP
  • elevated BUN
  • increased serum creatinine.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it should be stored in a tightly closed container. The storage temperature should be maintained between 1 to 30 degrees Celsius to preserve the efficacy of the drug.

Appearance and packaging

Appearance

A hard capsule with a blue upper part and a white lower part filled with a pale yellow powder.

Package unit

30, 300 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.