Medication info
Rhodopine Tablet 50 mg (Jotephin)

Rhodopine Tablet 50 mg (Jotephin)

Prescription medicationOral
Ingredient · strength
Zotepine›50mg / 1 tablet
Manufacturer / importer
Youngjin Pharmaceutical Co., Ltd.
Appearance
This medication is a light purple coated tablet.
Packaging
30 tablets/bottle, 500 tablets/bottle
Approval status
Active

MFDS item code 199701064 · Approved 1997.09.26 · Insurance code 642400250

Summary

Main use
Treatment of schizophrenia
Who takes it
Adults
Adult dose
The therapeutic dose of this medicine should be adjusted according to the patient's clinical condition, and the lowest effective dose possible should be administered. ○ Adults: Administer zotepine 75∼150 mg per day orally in divided doses. The dose may be increased up to 450 mg per day depending on symptoms. If the daily dose is 300 mg or more, administer doses at intervals of at least 4 hours.

Ingredients

Manufacturer
Youngjin Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of schizophrenia

  • Schizophrenia
View approved original text

This medication is used to alleviate the symptoms of schizophrenia.

How to take

Adult dose

The therapeutic dose of this medicine should be adjusted according to the patient's clinical condition, and the lowest effective dose possible should be administered. ○ Adults: Administer zotepine 75∼150 mg per day orally in divided doses. The dose may be increased up to 450 mg per day depending on symptoms. If the daily dose is 300 mg or more, administer doses at intervals of at least 4 hours.

Precautions

This medication may increase the risk of death in elderly patients with dementia, so caution is particularly necessary. For patients with cerebrovascular diseases, there may be an increased risk of stroke, so it should be used with caution. Due to the risk of venous thromboembolism, risk factors for thrombosis should be checked before and during use, and preventive measures should be taken. It should not be administered to patients in comatose states, patients in circulatory shock, patients taking central nervous system depressants, and patients using epinephrine. Patients with allergies to this medication or similar ingredients, patients with acute alcohol intoxication, patients with hematopoietic disorders, pregnant and nursing women, children, and patients taking certain medications should also not be administered this medication. Patients with specific health conditions such as brain disorders, liver disorders, heart diseases, respiratory diseases, seizure disorders, and the elderly should use this medication with caution, and symptoms of high fever or severe physical fatigue may appear. This medication may cause serious side effects such as neuroleptic malignant syndrome, abnormal electrocardiograms, paralytic ileus, and seizures, so if abnormal symptoms occur, administration should be stopped immediately and appropriate treatment should be received. Drowsiness or decreased concentration may occur, so driving or operating dangerous machinery should be avoided, and leukopenia may occur, requiring regular blood tests. This medication may interact with various drugs, so it is essential to consult with a healthcare professional when taking other medications and it is advisable not to take it with alcohol. Women who are pregnant or nursing should not take this medication, and its safety has not been established for children, so it should not be used in this population. In cases of overdose, central nervous system depression, blood pressure decrease, abnormal electrocardiograms, etc., may occur, so immediate medical attention should be sought. Keep this medication out of reach of children and do not transfer it to other containers. When using this medication, it has been reported that sudden unexplained deaths occur during treatment, so careful observation is required.

Side effects

Increased mortality, increased risk of cerebrovascular disease, venous thrombosis, worsening of coma, hypersensitivity reactions, hyperthermia reactions, worsening of liver dysfunction, worsening of blood disorders, rapid fluctuations in blood pressure, respiratory depression, convulsions, high fever, immobility, severe muscle rigidity, dysphagia, tachycardia, fluctuations in blood pressure, sweating, persistent fever, leukocytosis, elevated serum creatine phosphokinase, myoglobinuria, renal function decline, consciousness impairment, respiratory distress, circulatory collapse, signs of dehydration, acute renal failure, electrocardiogram changes, intestinal paralysis, loss of appetite, nausea, vomiting, constipation, abdominal distension, seizure episodes, involuntary movements around the mouth, hyponatremia, hypotonic hyponatremia, increased urinary sodium excretion, hypertonic urine, consciousness impairment, conduction disturbance, orthostatic dysregulation, hypotension, tachycardia, arrhythmias, respiratory distress, thromboembolism, diarrhea, stomatitis, increased appetite, abdominal discomfort, cholestasis, Parkinson's syndrome, finger tremors, flexibility, muscle rigidity, decreased activity, gait disturbance, facial rigidity, mask-like facies, dyskinesia, dysarthria, ocular rotation seizures, abnormal posture, inability to sit still, drowsiness, abnormal brain waves, nonsensical speech, depression, insomnia, anxiety, agitation, unrest, excitement, easily irritated, hypersexuality, increased talkativeness, exhaustion, post-occipital edema, asthma, visual field disturbances, sweat gland secretion disorders, weakness, fatigue, malaise, thirst, dizziness, headache, heaviness in the head, nasal congestion, urination difficulties, numbness, incontinence, sweating, increased urination, increased saliva production, carbohydrate metabolism disorders, sexual dysfunction, menstrual irregularities, galactorrhea, corneal opacity, lens opacification, accommodation disorders, glaucoma, facial flushing, phototoxic reactions, edema, rash, skin itching, drug reaction (DRESS), agranulocytosis, decreased serum uric acid, symptoms of systemic lupus erythematosus, visual impairment, fever, taste alteration, weight gain, weight loss, pupil dilation, drowsiness, central nervous system depression, hypotension, extrapyramidal symptoms, intense emotions, emotional instability

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture and should be kept away from direct sunlight at room temperature. This way, the efficacy of the medication can be maintained for a longer time.

Appearance and packaging

Appearance

This medication is a light purple coated tablet.

Package unit

30 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.