Samion Tablets 30 mg (Nisergoline)

Adult dose

* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally 2 ∼ 3 times daily before meals. Adjust the dose appropriately according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before meals. If the desired effect is not achieved at this dose, it may be increased to 60 mg. The dose may be reduced after symptoms improve. Reduce the dose in patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL).

This medication should not be used in certain patients. For example, individuals allergic to this medication or ergot alkaloids, those who have suffered from acute myocardial infarction, those with acute bleeding, those taking drugs that stimulate the sympathetic nervous system, individuals with very slow heart rates, those with unresolved bleeding in the head, and patients with orthostatic hypotension should not take this drug. Additionally, individuals with slightly slow heart rates or those with compromised kidney function should be especially cautious when using this drug. When taking this medication, gastrointestinal issues may rarely occur, including reduced appetite, diarrhea, constipation, nausea, vomiting, abdominal pain, and dry mouth. With respect to liver function, liver enzyme levels may rise. Moreover, cardiovascular symptoms such as dizziness, orthostatic hypotension, changes in blood pressure, and elevated blood uric acid levels may also occur rarely. Psychically, symptoms such as drowsiness, fatigue, headache, tinnitus, and insomnia may emerge, along with allergic reactions such as rashes, itching, flushing, or a sensation of heat. Taking this medication in conjunction with other antihypertensive agents may lead to excessively low blood pressure; therefore, it is important to check blood pressure frequently. Additionally, this drug may affect uric acid metabolism, so caution is required in individuals with gout or hyperuricemia. After taking this drug, caution is necessary when driving or operating machinery. This medication is metabolized by specific enzymes in the liver, so interactions may occur if taken with other drugs that share the same metabolic pathway. Women who are pregnant or breastfeeding should be particularly careful when taking this drug. Animal studies have reported potential harm to the fetus, so women who could become pregnant or are pregnant should consult their physician and make a careful decision. If breastfeeding, it is advisable to avoid taking this drug or discontinue breastfeeding, as it may be excreted in breast milk. Elderly patients may have reduced bodily functions; hence, they should use the medication cautiously, potentially at lower doses. Safety in pediatric patients has not yet been adequately established. In cases of overdose, transient hypotension may occur, so blood pressure changes must be monitored closely, and appropriate measures should be taken as needed. Finally, this medication should be kept in a safe place out of reach of children, and it is important to store it in its original container to maintain drug quality and prevent misuse.

Loss of appetite, diarrhea, constipation, nausea, vomiting, intermittent upper abdominal pain or cramps, thirst, elevated ALT, elevated AST, dizziness, postural hypotension, hypertension, elevated blood uric acid, blood pressure reduction, drowsiness, fatigue, headache, tinnitus, fatigue, insomnia, rash, urticaria, pruritus, flushing, heat sensation, nightmares, mood changes, indigestion

This medication is sensitive to light and should be stored in a tightly sealed container that does not allow light. The recommended storage temperature is room temperature between 1 degree Celsius and 30 degrees Celsius.

Appearance

It is a yellow film-coated tablet.

Package unit

For domestic use (30 tablets) - 30 tablets/bottle, For domestic use (100 tablets) - 100 tablets/bottle