Hapiseu Tablets (Acyclovir)

Adult dosage

1. Treatment of herpes simplex virus infections: Administer 200 mg 5 times a day at 4-hour intervals for 5 days. Treatment may be extended for severe primary infections. 2. Prevention of simplex herpes in immunocompetent individuals: Administer 200 mg 4 times a day at intervals of about 6 hours, or 400 mg twice daily at 12-hour intervals. 3. Prevention of simplex herpes in immunocompromised patients: Administer 200 mg 4 times a day at about 6-hour intervals.

Children's dosage

1. Treatment of herpes simplex infections and prevention in immunocompromised patients - Aged 2 and older: Follow adult dosing - Below 2 years: Administer 1/2 of adult dose 2. Treatment of chickenpox in children aged 2 and above: 1 dose of 20 mg per kg of body weight (maximum 800 mg), administered 4 times daily for 5 days.

This medicine should not be administered to patients who have had an allergic reaction to this drug or its components, and to those who have had an allergy to valacyclovir. Caution should be exercised when using this drug in patients with impaired kidney function due to the potential for neuropsychiatric side effects. For patients with impaired liver function, the risk of further liver impairment should be considered and administered with caution. Particular care should be taken when using this drug in infants and children, and elderly patients may also experience side effects more frequently, requiring caution. During the use of this medication, serious allergic reactions such as anaphylactic shock may rarely occur, so if symptoms such as difficulty breathing or chest tightness arise, use should be immediately discontinued, and medical attention should be sought. Skin rashes or hives may occur, and in severe cases, serious skin conditions like Stevens-Johnson syndrome may appear, so if these symptoms occur, medication should be stopped and consultation with a physician is necessary. Mental symptoms such as confusion, hallucinations, seizures, drowsiness, and anxiety may occur, particularly more frequently in elderly patients and those with compromised renal function. Kidney problems may arise, so any abnormalities in urination or the presence of hematuria or proteinuria should be reported immediately. Routine blood tests may show changes in white blood cell or platelet counts, so regular monitoring is required. If symptoms of liver dysfunction, jaundice, or hepatitis appear, immediate consultation with a physician is necessary. Gastrointestinal symptoms such as nausea, vomiting, diarrhea, and abdominal pain may occur, and if symptoms are severe, medication should be discontinued. It is important to maintain adequate hydration during treatment to prevent dehydration and reduce stress on the kidneys. To enhance treatment efficacy, it is best to administer this drug as soon as symptoms begin, and if symptoms do not improve, other treatment options should be considered. Women who are pregnant or of childbearing potential should use this medication with caution, and breastfeeding should be discontinued if using this drug. In cases of overdose, severe symptoms such as coma, seizures, and confusion may arise, requiring immediate medical attention for proper treatment. This medication may interact with other drugs, so it is essential to consult with a physician or pharmacist regarding any other medications being taken. Activities that require attention, such as driving or operating machinery, should be approached with caution while taking this drug, especially in patients with compromised renal function.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, anaphylactic shock, anaphylactoid reactions, severe skin adverse reactions (Stevens-Johnson syndrome, Lyell's syndrome), jaundice (yellowing of skin or eyes), liver dysfunction (jaundice), sudden and severe headaches, thunderclap headache, seizures, altered consciousness, vision disturbances, numbness, markedly reduced urine output, severe swelling throughout the body

Mild side effects

• Photosensitivity reactions
• fixed drug eruptions
• rashes
• fever
• vesicles
• alopecia
• erythema multiforme
• skin and mucous membrane syndrome
• toxic epidermal necrolysis
• alterations in consciousness

This medication should be stored in a tightly sealed container to protect it from air and moisture, preferably at room temperature between 1°C and 30°C. This storage condition helps to maintain the drug's efficacy safely.

Appearance

Light blue round tablets

Package unit

30 tablets/bottle, 200 tablets/bottle