Ciprofloxacin Tablets 250 mg (Ciprofloxacin Hydrochloride Hydrate)

Adult dose

For the typical adult, ciprofloxacin is administered orally as a single dose of 250 to 500 mg, twice a day between meals. In cases of severe complicated infections, the dose may be increased to 750 mg, twice a day. Treatment for acute infections usually lasts for 5 to 10 days, and even after symptoms have disappeared, it must be administered for at least an additional 3 days. Dosing should be adjusted according to renal impairment. The dose interval and amount may vary based on creatinine clearance.

This medication may cause serious adverse effects such as tendonitis, tendon rupture, peripheral neuropathy, and central nervous system symptoms; therefore, if any of these symptoms occur, the use of this medication should be stopped immediately. Special caution is required as symptoms may worsen in patients with myasthenia gravis. This medication should be used only when no alternative treatments are available for specific bacterial infections and is contraindicated in pregnant or potentially pregnant women, nursing mothers, adolescents under 18 years of age, and patients with epilepsy. Furthermore, elderly patients, patients with impaired renal function, and those with a history of seizures should use this medication with caution. As there may be many drug interactions, patients should inform their healthcare provider of any medications they are currently taking. This medication may increase the risk of seizures and potentially cause mental health issues; hence, if any psychiatric symptoms or seizures occur, immediate consultation with a healthcare provider is necessary. During treatment, strong sunlight or UV exposure should be avoided, and if any skin rashes or itching develop, the use should be discontinued. Additionally, as it may affect blood sugar control, diabetic patients should monitor their blood sugar closely. If there are any symptoms of pain, inflammation, or abnormalities in the tendons during treatment, rest should be taken immediately, and exercise should be avoided. In case of overdose, renal function should be closely monitored, and appropriate emergency care should be provided as necessary. Lastly, this medication should be kept out of reach of children and stored away from direct sunlight and UV light.

Serious side effects

Tendinitis, tendon rupture, exacerbation of severe myasthenia gravis, anaphylactic reaction, anaphylaxis-like shock, serum sickness-like reaction, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell syndrome), acute generalized exanthematous pustulosis (AGEP), hepatic necrosis, life-threatening liver failure, liver dysfunction, jaundice, hepatitis, acute renal failure, hematuria, crystalluria, interstitial nephritis, acute generalized exanthematous pustulosis, headache, and others.

Mild side effects

Fungal superinfection, antibiotic-associated colitis, eosinophilia, (thrombotic) venous inflammation, leukopenia, anemia, neutropenia, leukocytosis, thrombocytopenia, thrombocytosis, erythrocytopenia, decreased hemoglobin, decreased hematocrit, granulocytopenia, leukocytolysis, increased INR value, syndrome of inappropriate antidiuretic hormone secretion (SIADH), allergic reactions, allergic edema/angioedema, decreased appetite and weight.

This medication may be sensitive to air and moisture; thus, it must be stored in a tightly sealed container. It is recommended to keep the storage temperature between 1 degree and 30 degrees Celsius at room temperature. By doing so, the effectiveness of the medication can be preserved safely.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle