Medication info

Moarex Injection

Prescription medicationInjections
Ingredient · strength
L-Isoleucine›9.2gL-Leucine›9.45gL-Lysine Acetate›3.95gL-Methionine›0.44gL-Phenylalanine›0.3gL-Threonine›2.14gL-Tryptophan›0.7gL-Valine›8.9gL-Alanine›8.4gL-Arginine›15.37gL-Aspartic Acid›0.2gL-Histidine›3.1gL-Proline›5.3gL-Serine›2.6gL-Tyrosine›0.4gGlycine›5.4g
Manufacturer / importer
삼성제약(주)
Appearance
A colorless and transparent liquid-filled injection
Packaging
200 mL/bottle, 250 mL/bottle
Approval status
Active

MFDS item code 199500250 · Notified 1995.10.02

Summary

Main use
Improvement of encephalopathy due to chronic liver disease
Who uses it
Adults
Adult dosage
Generally, administer 500 mL by drip infusion. Typically, maintain the infusion rate for adults at 500 mL over 180 minutes or more. When administered via central venous catheter, mix 500 mL of this medication with carbohydrate solutions and continuously infuse into the central vein over 24 hours. Adjust appropriately based on age, symptoms, and body weight.

Ingredients

Manufacturer
삼성제약(주)

Efficacy & effects

Improvement of encephalopathy due to chronic liver disease

  • Encephalopathy due to chronic liver disease
View approved original text

This medication is used to improve the symptoms of encephalopathy caused by chronic liver disease. It alleviates conditions where liver function is impaired and affects the brain, helping to improve the patient's mental state and cognitive function. This contributes to enhancing the patient's quality of life.

Dosage and Administration

Adult dosage

Generally, administer 500 mL by drip infusion. Typically, maintain the infusion rate for adults at 500 mL over 180 minutes or more. When administered via central venous catheter, mix 500 mL of this medication with carbohydrate solutions and continuously infuse into the central vein over 24 hours. Adjust appropriately based on age, symptoms, and body weight.

Precautions

This medication must be used according to a doctor's instructions. This medication should not be used in patients with severely impaired kidney function or elevated nitrogen levels in the blood. Patients with liver dysfunction or amino acid metabolism problems should also avoid this medication. It is safer not to administer this medication to patients with heart and lung-related diseases such as heart failure or pulmonary edema. This medication should not be administered to patients with little or no urine output. Formulations containing sodium or chloride ions should be used with caution in patients with hypernatremia or alkalosis. If magnesium ions are included, this medication should not be administered to patients with atrioventricular block or severe myasthenia gravis. Administering this medication to patients with excess fluid may be hazardous. Patients with severe acidosis, heart failure, or edema due to sodium retention should use this medication cautiously. Patients with abnormal potassium levels or reduced kidney function should also use this medication with care. This medication contains sodium bisulfite, which may cause allergic reactions or asthma attacks, so asthmatic patients should take special precautions. Rashes or hypersensitivity reactions may occur rarely, and if such symptoms appear, the use should be stopped immediately. Gastrointestinal symptoms such as nausea or vomiting may occur. Symptoms related to the circulatory system may appear, such as rapid heartbeat or elevated blood pressure. Rapid, large doses may lead to acidosis, so caution is advised. Systemic symptoms such as chills, fever, headache, and difficulty breathing have been reported. If magnesium ions are included, peripheral vascular dilation may occur. Metabolic complications such as metabolic acidosis, electrolyte imbalances, and blood sugar abnormalities may occur, requiring caution. Patients with reduced liver or kidney function may have changes in blood test results, necessitating regular testing. Safety has not been established for pregnant women, so this should only be administered when the therapeutic benefit outweighs the risk. In children, due to immature liver function, dosing concentrations should be kept low, and blood ammonia levels should be checked frequently. Elderly patients, having diminished physical function, should have the infusion rate slowed and doses adjusted. This medication contains electrolytes, so care should be taken with large volumes to maintain electrolyte balance; rapid infusion may cause side effects. Sterile conditions must be strictly maintained during use, and solutions that are discolored or cloudy should not be used. When storing, do not open the packaging, and do not use if abnormalities are present.

Side effects and when to seek care immediately

Serious side effects

Hives, difficulty breathing, asthma attacks, shock, bronchospasm, respiratory arrest, severe swelling accompanied by hypertension

Mild side effects

  • Nausea
  • vomiting
  • rash
  • chest discomfort
  • palpitations
  • tachycardia
  • elevated blood pressure
  • chills
  • fever
  • headache
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  • peripheral vascular dilation
  • metabolic acidosis
  • hypophosphatemia
  • alkalosis
  • hyperglycemia
  • diabetes
  • osmotic diuresis and dehydration
  • rebound hypoglycemia
  • elevated liver enzymes
  • vitamin deficiencies and excesses
  • electrolyte imbalances
  • pediatric hyperammonemia
  • elevated BUN
  • serum amino acid imbalances
  • metabolic alkalosis
  • systemic nitrogen retention
  • hypersensitivity

Not everyone experiences these, and they can vary from person to person.

Storage

This medication must be stored in a sealed container to prevent air or moisture from entering. Additionally, it is advisable to store it at room temperature away from direct sunlight and not too hot or too cold.

Appearance and packaging

Appearance

A colorless and transparent liquid-filled injection

Package unit

200 mL/bottle, 250 mL/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.