Pugasin Tablets 100 mg (Ofloxacin)

Adult dosage

○Adults: Usually, take 300～600 mg ofloxacin per day in 2～3 divided doses. ○For Hansen's disease, take 400～600 mg of this drug per day in 2～3 divided doses. In principle, use in combination with other anti-Hansen's disease drugs. Adjust the dose as appropriate according to age and symptoms.

This drug is a fluoroquinolone antibiotic used to treat specific bacterial infections. When taking this drug, serious side effects such as tendon-related problems like tendonitis or tendon rupture, peripheral neuropathy, central nervous system anomalies, and worsening of myasthenia gravis may occur, so caution is very important. In particular, patients with severe myasthenia gravis should not use this drug as it may worsen symptoms. Moreover, this drug should only be used when there are no other treatment options for certain infections such as acute bacterial rhinosinusitis, acute exacerbation of chronic bronchitis, simple urinary tract infections, and acute otitis media. Concurrent use of this drug and corticosteroids may increase the risk of tendon rupture, so they should not be used together, and the intake should be immediately stopped if pain or inflammation occurs. Elderly patients, patients with reduced kidney function, patients with solid organ transplants, etc., are at a higher risk of tendon rupture and should be particularly cautious. This drug has neuromuscular blocking effects, which can cause serious adverse reactions in patients with severe myasthenia gravis, so caution is required. Individuals with a history of allergic reactions to this drug or others in the same class, history of tendonitis or tendon rupture, individuals under 18 years of age, pregnant or breastfeeding women, patients with certain enzyme deficiencies, or those with seizure disorders should not use this drug. Patients with severe kidney impairment, older age, mental health disorders, liver disorders, and aortic aneurysms or heart valve disease should consult with a physician before administration. While taking this drug, various side effects such as allergic reactions, liver or kidney dysfunction, gastrointestinal issues, blood abnormalities, neurological symptoms, skin disorders, musculoskeletal issues, respiratory problems, and cardiovascular issues may occur, so if unusual symptoms arise, consult a doctor immediately. Additionally, this drug can increase sensitivity to sunlight, potentially leading to skin rashes or phototoxic reactions, so strong sunlight exposure should be avoided, and the intake should be discontinued if symptoms occur. Diabetic patients who require blood sugar control may experience fluctuations in blood sugar levels while taking this drug, so blood sugar should be monitored closely. This drug may interact with various other medications, so if other drugs are being taken, it is essential to inform the doctor or pharmacist, particularly when used with anticoagulants, certain anti-inflammatories, certain antacids, and diabetes treatments. Pregnant or breastfeeding women should not take this drug, and breastfeeding should be suspended during treatment. The safety of this drug in pediatric and adolescent patients has not been established, so it is not used in these populations. Elderly patients may experience prolonged presence of the drug in the body due to reduced kidney function, necessitating dose adjustment and care. Dizziness or drowsiness may occur while taking this drug, requiring caution when driving or operating machinery. In the case of overdose, prompt medical attention is needed, and this drug is not completely eliminated by hemodialysis. This drug should be administered slowly via intravenous injection and should not be administered with certain solutions. Finally, this drug should be kept out of reach of children and should not be transferred to other containers for safety.

• Tendonitis
• tendon rupture
• peripheral neuropathy
• central nervous system effects
• exacerbation of myasthenia gravis
• anaphylactic shock
• anaphylactoid reactions
• rash
• itching
• redness

This drug should be stored in a tightly sealed container to prevent air or moisture from entering, and it is best kept in a cool room temperature. It is important to avoid direct sunlight and not to store it in excessively hot or cold places.

Appearance

It is a round film-coated tablet that is white to slightly off-white.

Package unit

30 tablets/bottle, 500 tablets/bottle