Keploxine Tablet (Ofloxacin)

Adult dosage

○ The usual adult dose of ofloxacin is 300～600 mg per day, taken in 2～3 divided doses. ○ For Hansen's disease, the dose is 400～600 mg per day, taken in 2～3 divided doses. In principle, administer in combination with other anti-Hansen's disease drugs. Adjust the dose as appropriate according to age and symptoms.

This medication can cause tendon-related disorders such as tendinitis and tendon rupture. If you experience pain or inflammation in the tendons while taking this medication, you must stop using it immediately. Peripheral neuropathy and central nervous system adverse effects can also occur, so caution is needed if sensory abnormalities or neurological issues are experienced. This drug should not be used in patients with myasthenia gravis as it may worsen symptoms. This medication should only be used when there are no alternative treatments for specific bacterial infections. The risk of tendon rupture is increased in the elderly, patients with impaired renal function, and those taking corticosteroids. Correlating the drug with corticosteroids should be avoided and if tendon issues are suspected, the medication should be stopped immediately and rest should be taken. Seizures or central nervous system adverse effects may occur, so patients with a history of brain-related disorders should be especially cautious. Pregnant or breastfeeding women, adolescents under 18 years of age, and those allergic to this drug or similar medications should not take it. Regular liver and kidney function tests are necessary during administration, and adequate hydration is required. During the course of this medication, sun exposure or artificial ultraviolet light should be avoided, and if skin rash or hypersensitivity reactions appear, usage should be stopped immediately. Neurological adverse symptoms such as dizziness or drowsiness may occur, requiring caution in driving or operating dangerous machinery. Patients with diabetes may experience fluctuations in blood glucose levels while taking this medication, so blood sugar should be monitored frequently. This drug can interact with various medications, so if other drugs are being taken, consultation with a doctor or pharmacist is essential.

Tendonitis, tendon rupture, peripheral neuropathy, central nervous system effects, exacerbation of myasthenia gravis, anaphylactic shock, anaphylactic reaction, rash, pruritus, erythema, edema, fever, warmth, vesicles, erythema, phototoxic reaction, hematuria, acute kidney failure, kidney stones, interstitial nephritis, elevated BUN, elevated serum creatinine, jaundice, liver failure, elevated AST/ALT, elevated ALP, elevated γ-GTP, increased total bilirubin, cholestasis jaundice, fulminant hepatitis, membranous colitis, colitis accompanied by hematochezia, abdominal pain, frequent diarrhea, nausea, vomiting, gastrointestinal discomfort, diarrhea, cirrhosis, loss of appetite, upper abdominal pain, dyspepsia, chest pain, thirst, taste disturbance, stomatitis, glossitis, abdominal distension, constipation, dysphagia, gastrointestinal hemorrhage, oral mucosal pain, intestinal perforation, anemia, leukopenia, decreased hemoglobin, decreased hematocrit, thrombocytopenia, eosinophilia, agranulocytosis, thrombocytopenic purpura, petechiae and purpura, prolonged prothrombin time, reversible bone marrow suppression, lymphopenia, neutropenia, elevated ESR, insomnia, dizziness, headache, convulsions, tremors, paresthesia, peripheral nerve disorders, visual disturbances, auditory disturbances, hallucinations, drowsiness, nervousness, sleep disorders, somnolence, anxiety, depression, restlessness, hypomania, delirium, seizures, nightmares, paranoia, disorientation, attention deficit, memory impairment, delirium, suicidal ideation, suicide, perceptual disturbances, reversible olfactory and vestibular sensory disturbances, ataxia, aphasia, heaviness of head, skin mucous membrane syndrome, toxic epidermal necrolysis, arthralgia, myalgia, muscle weakness, myositis, rhabdomyolysis, pharyngitis, respiratory distress, bronchospasm, allergic pneumonia, epistaxis, stridor, fever, cough, abnormal chest X-ray, eosinophilia, interstitial pneumonia, cerebral thrombosis, pulmonary edema, tachycardia, hypertension, hypotension, palpitations, vasodilation, circulatory collapse, QT prolongation, ventricular tachycardia, dysuria, polyuria, urinary retention, anuria, polyuria, hematuria, urinary storage, pyuria, diabetes, proteinuria, alkaline urine, vulvovaginitis, vaginal candidiasis, increased vaginal discharge, itching of the female genitalia, menstrual irregularities, uterine cramps, female genital rash, pain, irritation, burning sensation, symptoms of hypoglycemia, limb pain, fatigue, fever, drowsiness, nausea, facial flushing, facial edema, paresthesia, imprecise speech, loss of directional sense

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

White to slightly yellow, round, film-coated tablet

Package unit

Company packaging unit