Aprogen Naproxen Sodium Tablet

Adult dose

1. Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis: Administer 275-550 mg of naproxen sodium orally twice a day (every 12 hours). 2. Acute gout: Administer an initial dose of 825 mg of naproxen sodium orally, and then 275 mg orally every 8 hours until the attack subsides. 3. Skeletal muscle disorders, postoperative pain, pain after tooth extraction, dysmenorrhea, tendinitis, bursitis: Administer an initial dose of 550 mg of naproxen sodium orally, followed by 275 mg every 6-8 hours. Do not exceed a total daily dose of 1350 mg. 4. Migraine: Administer an initial dose of 825 mg of naproxen sodium orally. If necessary, an additional 275-550 mg may be administered within 30 minutes after the initial dose. Do not exceed a total daily dose of 1350 mg. Adjust based on age and symptoms.

This medication may cause gastrointestinal bleeding if taken by someone who regularly consumes more than three alcoholic drinks a day, so it is essential to consult a doctor or pharmacist. This medication may increase the risk of cardiovascular disease, potentially leading to serious problems such as myocardial infarction or stroke, thus patients with cardiovascular diseases or risk factors should take extra caution. Serious gastrointestinal adverse reactions such as gastrointestinal bleeding, ulcers, and perforation may occur, especially in the elderly or those with a history of gastrointestinal diseases, so immediate consultation with medical personnel is required if symptoms arise. Patients with peptic ulcers, severe blood disorders, liver impairment, heart failure, severe hypertension, or an allergy to any ingredient in this medication should avoid taking it. Allergic reactions such as hypersensitivity, urticaria, and respiratory distress may rarely occur; if such symptoms appear, discontinue use immediately and consult a doctor. This medication may affect liver and kidney function; therefore, patients with liver or kidney diseases or a history thereof should use it with caution. During pregnancy, especially in the later stages, this medication can harm the fetus, so it is advisable for pregnant women to avoid taking it. Breastfeeding women should not take this medication, as it may be transmitted through breast milk and affect the baby. In children, especially in those under 2 years old, safety has not been established, so administration should be avoided; in the elderly, the risk of side effects is higher, so it should be used cautiously at the minimum dose. This medication may increase the risk of adverse effects when combined with other non-steroidal anti-inflammatory drugs or specific medications, so inform the healthcare provider if any other medications are being taken. If unusual reactions or uncomfortable symptoms occur while taking this medication, consult a doctor immediately; in cases of overdose, symptoms such as drowsiness, nausea, and vomiting may occur, so visit a medical institution immediately. Keep this medication out of the reach of children and do not transfer it to another container.

Serious side effects

• Urticaria
• severe swelling (edema)
• chest tightness
• difficulty breathing
• cold sweat
• paleness
• hematemesis
• gastrointestinal bleeding
• peptic ulcer
• perforation

Mild side effects

• Nausea
• stomach pain
• abdominal pain
• vomiting
• loss of appetite
• indigestion
• heartburn
• diarrhea
• constipation
• stomatitis

Drug interactions

Do not take this medication in conjunction with other non-steroidal anti-inflammatory drugs, naproxen derivatives, aspirin, or high-dose methotrexate. Additionally, avoid combining with hydantoin anticonvulsants, sulfonamides, sulfonylurea hypoglycemic agents, propranolol and other beta-blockers, ACE inhibitors (such as captopril), loop diuretics and thiazide diuretics, probenecid, lithium, low-dose methotrexate, and coumarin anticoagulants (such as warfarin).

Store this medication in a tightly sealed container to avoid exposure to air and moisture. It is also recommended to store it at room temperature between 1 and 30 degrees Celsius.

Appearance

Pale blue oval film-coated tablet

Package unit

10 tablets/PTP