Dialanyl PD-Two Liquid 2.5%

Adult dosage

It is used solely for intraperitoneal administration and is not for intravenous use. Infusion volume should be administered at a comfortable rate for the patient over approximately 10-20 minutes. For adults, an intraperitoneal volume of 2.0L～2.5L is typically injected based on a body surface area of 1.73m2. Continuous ambulatory peritoneal dialysis (CAPD) is usually conducted 4 times a day, and automated peritoneal dialysis (APD) is done 4-5 cycles overnight and up to 2 times during the day. Exchange volume,

This drug is used for peritoneal dialysis treatment, and discontinuing peritoneal dialysis may pose a life-threatening risk without alternative renal replacement therapy. Severe complications such as encapsulating peritoneal sclerosis may rarely occur during peritoneal dialysis, so caution is required. This drug contains dextrose, and patients allergic to corn or corn-containing products may experience severe allergic reactions; thus, allergy status must be confirmed before use. Patients with severe lactic acidosis or suspected metabolic disorders related to lactate should not use this drug, and the occurrence of lactic acidosis during treatment should be monitored periodically. Since there may be interactions with medications used for other underlying conditions, especially patients taking cardiac glycosides should carefully monitor serum potassium levels. Diabetes patients should closely monitor blood sugar changes during and after dialysis and adjust the doses of insulin or other blood glucose control agents as necessary. This drug should not be used in specific patient populations where peritoneal dialysis is difficult, such as those with diaphragm defects, abdominal burns, severe peritoneal adhesions, metabolic disorders related to lactate, and severe electrolyte imbalances. When using this drug, it is essential to maintain a sterile environment and administer it cleanly to minimize the risk of infection such as peritonitis. During peritoneal dialysis, weight, fluid status, electrolyte levels, blood glucose, nutritional status, etc., should be regularly checked to manage any abnormalities. In case of overdose, dehydration, electrolyte imbalance, or hyperglycemia may occur, necessitating immediate medical attention, and excessive dialysis solution should be promptly drained from the abdominal cavity. Ensure that the container is completely sealed, do not use solutions that are discolored or cloudy, and when heating, only use dry heat methods, not water or microwave. Pregnant or breastfeeding women should consult their physician thoroughly regarding the necessity of using this drug and carefully weigh the risks and benefits. In children, dosage should be adjusted according to their weight and age, and in the elderly, consideration should be given to the risk of hernia development. This drug is exclusively for peritoneal dialysis and should not be used for other purposes or as an injectable agent. If any abnormal symptoms or allergic reactions occur during peritoneal dialysis, medical personnel should be notified immediately, and regular monitoring is necessary during treatment.

Serious side effects

• Hives, severe swelling (edema), difficulty breathing, chest tightness, cold sweat, pallor → severe allergic reaction
• High fever and severe rash, blisters, skin peeling, oral/eye mucosal pain → severe skin adverse reaction
• Shortness of breath or difficulty breathing, asthma attacks, coughing with fever → respiratory issues
• Yellowing of the skin or eyes (jaundice), general fatigue → liver issues (jaundice)
• Sudden and extremely severe headaches.

Mild side effects

Abdominal pain, bleeding, peritonitis (abdominal pain, cloudy effluent sometimes accompanied by fever), inflammation around the abdominal catheter (redness, discharge), catheter breakage, difficulty in drainage, nausea, abdominal pain, diarrhea, constipation, hemorrhoids, vomiting, loss of appetite, abdominal distension, hypokalemia, hyponatremia, hypercalcemia, hypophosphatemia, hyperlactatemia, hypomagnesemia, hypercholesterolemia, hypertriglyceridemia, metabolic acidosis, hypoproteinemia, hyperblood.

This drug should be stored in a sealed container and kept at room temperature between 1 to 30 degrees Celsius. Storing it this way ensures the effectiveness of the medication is safely maintained.

Appearance

It is a colorless and transparent liquid formulation, sealed in a transparent polyvinyl chloride bag with a pale yellow tint. 5L/bag (automatic peritoneal dialysis) is injected into the peritoneal dialysis solution bag in the order of infusion line, inner stopper, connector, and rubber ring.

Package unit

2000, 2500ml/2 bags, 5000ml/bag