Pavise Ofloxacin Tablets

Adult dose

○ The usual adult dose of ofloxacin is 300～600 mg per day, divided into 2～3 doses. ○ For leprosy, the dose is 400～600 mg per day, divided into 2～3 doses. In principle, it should be used in combination with other antileprosy drugs. The dose may be adjusted as appropriate according to age and symptoms.

This medication can cause serious tendon issues such as tendonitis and tendon rupture; if such symptoms occur, you must immediately stop taking the medication. It can affect peripheral neuropathy and the central nervous system, potentially leading to sensory disturbances or neurological issues, so caution is required. In patients with myasthenia gravis, this medication may worsen symptoms, so it is advisable not to use it. It should only be used restrictively for certain infections, such as acute bacterial sinusitis, acute exacerbations of chronic bronchitis, and uncomplicated urinary tract infections. Elderly individuals or those using steroids may be at a higher risk for tendon rupture, so exercise caution. Patients with a history of allergic reactions or tendon problems from this medication or similar drugs should not take it. It is safest not to use this medication in pregnant women, nursing mothers, adolescents under 18 years of age, or patients with certain genetic conditions. Patients with impaired kidney or liver function, a history of mental illness, aortic aneurysms, or heart valve diseases should use this medication cautiously. This medication can cause various side effects such as allergic reactions, liver dysfunction, kidney problems, gastrointestinal disorders, blood abnormalities, and neurological issues; if any unusual symptoms appear, immediate consultation with a healthcare professional is necessary. While taking this medication, it is advisable to avoid exposure to sunlight or ultraviolet rays, ensure adequate hydration, and exercise caution while driving or operating hazardous machinery. This medication may interact with other drugs, so inform your healthcare provider, especially if taking anticoagulants, antidiabetic agents, or certain anti-inflammatory drugs. Women who are pregnant or may become pregnant should not take this medication, and nursing mothers should discontinue breastfeeding while using it. Its safety in children and adolescents has not been confirmed, so it is not used in these populations. In cases of overdose, severe symptoms may arise; therefore, adherence to the prescribed dosage and administration is crucial. Intravenous administration should be done slowly, and it should not be administered with certain solutions. This medication should be kept out of the reach of children and not transferred to other containers.

Tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects, exacerbation of myasthenia gravis, anaphylactic shock, anaphylactoid reactions, rash, itching, erythema, edema, fever, heat sensation, vesicles, erythema, photosensitivity reactions, hematuria, acute renal failure, kidney stones, interstitial nephritis, elevated BUN, elevated serum creatinine, jaundice, liver failure, elevated AST/ALT, elevated ALP, elevated γ-GTP, elevated total bilirubin, obstructive jaundice, fulminant hepatitis, membranous colitis, abdominal pain, diarrhea, nausea, vomiting, discomfort in the stomach/abdomen, cirrhosis, appetite loss, gastric discomfort, dyspepsia, chest pain, thirst, taste alteration, stomatitis, glossitis, abdominal distension, constipation, dysphagia, gastrointestinal bleeding, oral mucosal pain, bowel perforation, anemia, leukopenia, decreased hemoglobin, decreased hematocrit, thrombocytopenia, eosinophilia, agranulocytosis, thrombotic thrombocytopenic purpura, petechial and ecchymotic hemorrhages, prolonged prothrombin time, reversible bone marrow suppression, lymphopenia, neutropenia, increased ESR, insomnia, dizziness, headache, seizures, tremors, paresthesia, peripheral nerve disorders, visual disturbances, auditory disturbances, hallucinations, drowsiness, neurosensitivity, sleep disturbances, confusion, anxiety, depression, agitation, fatigue, delirium, perceptual disturbances, reversible olfactory and proprioceptive dysfunction, ataxia, aphasia, feeling of heaviness in the head, mucocutaneous syndrome, toxic epidermal necrolysis, arthralgia, myalgia, muscle weakness, myositis, malaise, elevated CPK, elevated serum and urine myoglobin, rhabdomyolysis, pharyngitis, respiratory distress, bronchospasm, allergic pneumonia, epistaxis, wheezing, fever, cough, abnormal chest X-ray, eosinophilia, interstitial pneumonia, cerebral thrombosis, pulmonary edema, tachycardia, hypertension, hypotension, palpitations, vasodilation, circulatory collapse, prolonged QT interval, ventricular tachycardia, dysuria, frequency of urination, urinary retention, anuria, polyuria, hematuria, dysuria, pyuria, diabetes, proteinuria, alkaline urine, vaginitis, vaginal candidiasis, increased vaginal discharge, itching of the female external genitalia, menstrual irregularities, uterine cramps, female genital rash, pain, irritation, burning sensation, symptoms of hypoglycemia, limb pain, malaise, fever, drowsiness, nausea, dizziness, facial flushing, facial edema, paresthesia, inaccurate speech, loss of directional sense

This medication should be stored in a tightly sealed container to prevent air exposure and kept at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness and prevent deterioration.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle