Dilatrend 25mg (Carvedilol)

Adult dose

Do not increase the dose or discontinue treatment without consulting a physician. 1. Essential hypertension 1) Adults (1) For the first 2 days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is required, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Elderly patients In some elderly patients, 12.5 mg once daily may provide an adequate effect. However, the dose may be increased if the effect is insufficient after 2 weeks of treatment. 2. Chronic stable angina 1) For the first 2 days, administer 12.5 mg of this product per dose orally twice daily, then administer 25 mg per dose orally twice daily. 2) The usual dose is 25 mg per dose twice daily for 2 weeks. If a dose increase is required (excluding elderly patients), the dose may be increased to 50 mg per dose twice daily. 3. Congestive heart failure Before starting treatment with this product, the standard treatment regimen already being administered (conventional treatment for chronic heart failure with an ACE inhibitor, a diuretic, and usually a digitalis preparation) should be stable. Fluid retention should also be minimized before starting treatment with this product. 1) The usual initial dose is 3.125 mg of this product per dose orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg per dose twice daily for 2 weeks, then to 12.5 mg per dose twice daily for 2 weeks, and then to 25 mg per dose twice daily. 2) Increase the dose gradually after administering each dose level for at least 2 weeks, until the dose tolerated by the patient is reached. 3) The effective minimum dose is 6.25 mg per dose twice daily. The maximum dose is 25 mg per dose twice daily for patients weighing 85 kg or less, and 50 mg per dose twice daily for patients weighing more than 85 kg. 4) To control the rate of absorption, it is recommended that the product be taken with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

This medication should not be used in certain patients. For example, individuals who have had an allergic reaction to this drug or any of its components should not take it. Patients with severely impaired heart function or in a state of cardiac shock may experience a deterioration of their condition if this drug is used. Additionally, those with excessively slow heart rates or conduction issues should avoid this medication. For individuals with right heart failure due to cor pulmonale or pulmonary hypertension, symptoms may worsen with this medication. Patients with diabetic ketoacidosis or metabolic acidosis should be cautious, as heart function may be further suppressed. Patients with severely impaired or unstable heart failure, as well as those with a history of bronchospasm such as asthma or chronic obstructive pulmonary disease, may experience worsened symptoms from this medication. Women who are pregnant or possibly pregnant, as well as nursing mothers, should not use this medication. Patients with genetic metabolic disorders such as lactose intolerance should also avoid this medication. This medication should be used cautiously in patients with diabetes, severe allergic reactions, poor heart function, or reduced kidney or liver function. Older adults, patients with low blood pressure, and those with conduction abnormalities need to exercise increased caution when taking this medication. When starting the medication or increasing the dosage, dizziness, fatigue, and headaches may occur, and regular heart function tests should be performed. If the heart rate becomes too slow or blood pressure drops too low, dosage adjustments or discontinuation may be necessary. This medication may interact with other drugs; therefore, if you are taking other medications, it is essential to inform your doctor or pharmacist. Special caution is needed when taking it with antihypertensives, diabetes medications, antidepressants, sedatives, calcium channel blockers, and antiarrhythmics, as side effects may worsen. Additionally, taking it with alcohol or grapefruit juice may alter the effects of the medication, so it is advisable to avoid these. Pregnant or nursing women should avoid taking this medication, as it may pose risks to the fetus or newborn. The safety of this medication in children or adolescents under 18 years has not been established, and its use is not recommended. When administering this medication to elderly patients, caution must be taken due to decreased liver function which may increase blood concentration; start with a low dose and monitor closely. In cases of overdose, blood pressure may drop sharply, or heart rate may slow excessively, leading to heart function issues; therefore, immediate contact with medical services is necessary for appropriate treatment. During use, exposure to light may cause discoloration, so store in an opaque container and keep out of reach of children.

• Dizziness
• headache
• fatigue
• weakness
• hallucinations
• confusion
• depression
• sleep disorder
• nightmares
• psychosis

This medication is sensitive to light, so it should be stored in a container that excludes light. It is best kept at a temperature between 1 degree and 30 degrees Celsius. This ensures that the drug's efficacy is well-maintained and prevents degradation.

Appearance

White round tablets

Package unit

100 tablets (10 tablets/PTP X 10)