Sarium Capsule (Flunarizine Hydrochloride)

Adult dose

1. Severe refractory migraine Initial dose: Administer 10㎎ of flunarizine orally once daily in the evening to adults younger than 65 years (5㎎ per dose in those 65 years of age and older). Discontinue treatment if depression, extrapyramidal symptoms, or other serious adverse reactions occur, or if symptoms do not improve after 2 months of treatment. Maintenance dose: If maintenance therapy is required, reduce the dose by administering 10㎎ of this product (5㎎ per dose in those 65 years of age and older) every other day, or 10㎎ once daily for 5 days a week (5㎎ per dose in those 65 years of age and older), with no doses for 2 days. In addition, for maintenance therapy to prevent migraine, discontinue treatment 6 months after the initial dose even if migraine symptoms have not occurred, and restart from the initial dose only if symptoms recur. 2. Dizziness due to functional disorders of the vestibular system: The dosage and administration are the same as for migraine, but the initial dose should not be continued longer than the period required to control dizziness (generally 2 months). Also, discontinue treatment if there is no clear improvement in symptoms after taking the product for 1 month for chronic dizziness or 2 months for paroxysmal dizziness. Adjust the dose appropriately according to age and symptoms.

This medication should not be administered to patients with incomplete hemostasis after intracranial bleeding, acute myocardial infarction, Parkinson's disease, a history of or symptoms of depression, and pregnant or potentially pregnant women. In addition, this medication contains lactose and should not be used in patients with genetic problems such as galactose intolerance, lactase deficiency, or glucose-galactose malabsorption. It should be administered cautiously to patients with liver dysfunction or elderly individuals, and it is important to monitor the patient's condition frequently during administration. Taking this medication may cause side effects such as drowsiness, depression, increased appetite, constipation, myalgia, menstrual irregularities, and weight gain. If depression or extrapyramidal symptoms (decreased motor function, rigidity, tremors, etc.) occur, discontinue administration immediately and seek appropriate treatment. Abnormal liver function may occur, so liver enzyme levels such as AST and ALT should be monitored regularly, and if abnormalities are detected, drug usage should be stopped. Allergic reactions may occur and manifest as skin rashes; if a rash or other hypersensitivity symptoms appear, consult a doctor immediately. This medication may cause drowsiness or weakness, so caution is required during driving or operating dangerous machinery. When used with antihypertensives, dosage adjustments for the antihypertensives may be necessary, and when combined with alcohol, tranquilizers, or sleeping pills, excessive sedation may occur, so caution is advised. Pregnant or breastfeeding women are advised to avoid this medication, and if unavoidable, breastfeeding should be discontinued. Safety has not been confirmed for children, so it should not be used in pediatric patients. In case of overdose, symptoms such as sedation, excitation, and rapid heartbeat may occur, so immediate appropriate medical treatment should be sought.

• Rhinitis
• increased appetite
• depression
• drowsiness
• constipation
• muscle pain
• irregular menstruation
• breast pain
• weight gain
• gastrointestinal discomfort

This medication should be stored in a sealed container to prevent air and moisture from entering. It should be kept at room temperature, away from direct sunlight, in a place that is not too hot or too cold.

Appearance

A hard capsule with a gray upper part and a red lower part containing white powder

Package unit

30 capsules/bottle, 500 capsules/bottle