Loisol Injection (Ambroxol Hydrochloride)

Adult administration

As Ambroxol Hydrochloride, administer 15 mg per dose slowly by intravenous injection 2 to 3 times a day. In severe cases, it can be increased up to 30 mg per dose and may be administered as an infusion with physiological saline or Ringer's solution.

Child administration

For this medication, administer 1.2 to 1.6 mg per kg of body weight slowly by intravenous injection daily. For children over 5 years: 15 mg per dose 2 to 3 times a day, for ages 2 to 4 years: 7.5 mg per dose 3 times a day, for under 2 years:

This medication is provided in glass ampoules, so care must be taken when opening the ampoule to avoid glass fragments mixing in. Particularly when used in children and the elderly, it is essential to be cautious when opening the ampoule. Do not use if allergic to this medicine or its ingredients. Administer with caution to patients with poor kidney function, severe liver dysfunction, and infants under 2 years old. There may be rare occurrences of serious skin conditions while using this drug; if any skin or mucosal abnormalities occur, discontinue use immediately and consult a healthcare professional. Gastrointestinal discomfort may occur, and symptoms such as nausea, vomiting, heartburn, and dry mouth may manifest. Allergic reactions such as skin rash, urticaria, facial swelling, and difficulty breathing may occur rarely; notify healthcare personnel immediately if such symptoms occur. Inflammation of the respiratory system may occur, and neurological symptoms such as altered taste sensation or changes in taste have been reported. When used with certain antibiotics, this drug may increase the concentration of the antibiotic, and caution is necessary when combined. Use of this drug is not recommended during pregnancy, especially within the first three months, and if breastfeeding, it should be decided carefully as it may be transferred through breast milk. Elderly patients may have diminished bodily functions, so dosage adjustments and caution are necessary. No specific symptoms have been reported with overdose, but appropriate treatment is needed if adverse reactions occur. Headaches, leg pain, and extreme fatigue may occur during injection, so it is advisable to administer slowly. This drug should only be mixed with physiological saline or Ringer's solution for infusion, and it must be administered within 24 hours after mixing. Finally, it should be stored in a safe place out of reach of children.

Serious side effects

Urticaria, angioedema, difficulty breathing, severe acute anaphylaxis reaction, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell syndrome).

Mild side effects

Dyspepsia, nausea, vomiting, heartburn, dry mouth, abdominal discomfort, gastric and abdominal bloating, gastric and abdominal pain, diarrhea, constipation, loss of appetite, skin rashes, urticaria-like erythema, itching, facial swelling, chills, purulent rhinitis accompanied by leukocytosis, altered taste sensation, changes in taste, oral paralysis, arm numbness, headaches, leg pain, extreme fatigue.

This medication is sensitive to light, so it should be stored in a container that blocks light. Additionally, it should be stored in a temperature range of 1°C to 30°C, avoiding overly hot or cold conditions.

Appearance

A colorless, transparent liquid contained in a brown ampoule.

Package unit

2 mL/ampoule x 50