Medication info
Zanapam Tablet 0.4mg (Alprazolam)

Zanapam Tablet 0.4mg (Alprazolam)

Prescription medicationTabletOral
Ingredient · strength
Alprazolam›0.4mg / 1 tablet
Manufacturer / importer
Myungin Pharmaceutical Co., Ltd.
Appearance
Orange round tablets
Packaging
30 tablets/bottle, 200 tablets/bottle
Approval status
Active

MFDS item code 199304455 · Approved 1993.12.30 · Insurance code 651901740

Summary

Main use
Relief of symptoms of anxiety (including with coexisting depression), panic disorder, and psychosomatic disorders
Who takes it
Adults
Adult dose
Determine the dose individually to achieve maximum benefit. The usual daily doses listed below are appropriate for most patients, but higher doses may be required. In such cases, increase the dose gradually to avoid adverse reactions. The risk of dependence may increase with the dose and duration of administration. Therefore, administer the lowest effective dose for the shortest possible period, and frequently reassess the need for continued treatment. ○ Adults 1. As alprazolam, initiate treatment with 0.25-0.5㎎ per dose 3 times daily, up to a maximum dose of 4㎎ daily. For elderly patients, patients with hepatic impairment, and debilitated patients, initiate treatment with 0.25㎎ per dose 2-3 times daily. Reduce the dose if adverse reactions occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ of this medicine orally in 3 divided doses daily. If increasing the dose, increase gradually to a maximum of 2.4㎎ daily, administered orally in 3-4 divided doses. For elderly patients, initiate treatment with 0.4㎎ per dose 1-2 times daily, up to a maximum dose of 1.2㎎ daily. 3. Panic disorder Start with 0.5㎎ of this medicine and, according to the patient's response to treatment, increase by no more than 1㎎ at intervals of 3-4 days, to an average daily dose of 5-6㎎, divided into 3-4 doses. To discontinue treatment, reduce the dose by no more than 0.5㎎, usually at 3-day intervals; an even lower dose reduction may be required.

Ingredients

Manufacturer
Myungin Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of symptoms of anxiety (including with coexisting depression), panic disorder, and psychosomatic disorders

  • Anxiety disorder
  • anxiety symptoms
  • anxiety associated with depression
  • anxiety in psychosomatic disorders
  • tension
  • depression
  • sleep disorders
  • panic disorder
View approved original text

This medication is used for the short-term relief of anxiety disorders and symptoms of anxiety. It also helps improve anxiety symptoms associated with depression. It is effective for anxiety, tension, depression, sleep disorders associated with psychosomatic disorders. It is used in the treatment of panic disorders and helps manage and improve various symptoms related to anxiety.

How to take

Adult dose

Determine the dose individually to achieve maximum benefit. The usual daily doses listed below are appropriate for most patients, but higher doses may be required. In such cases, increase the dose gradually to avoid adverse reactions. The risk of dependence may increase with the dose and duration of administration. Therefore, administer the lowest effective dose for the shortest possible period, and frequently reassess the need for continued treatment. ○ Adults 1. As alprazolam, initiate treatment with 0.25-0.5㎎ per dose 3 times daily, up to a maximum dose of 4㎎ daily. For elderly patients, patients with hepatic impairment, and debilitated patients, initiate treatment with 0.25㎎ per dose 2-3 times daily. Reduce the dose if adverse reactions occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ of this medicine orally in 3 divided doses daily. If increasing the dose, increase gradually to a maximum of 2.4㎎ daily, administered orally in 3-4 divided doses. For elderly patients, initiate treatment with 0.4㎎ per dose 1-2 times daily, up to a maximum dose of 1.2㎎ daily. 3. Panic disorder Start with 0.5㎎ of this medicine and, according to the patient's response to treatment, increase by no more than 1㎎ at intervals of 3-4 days, to an average daily dose of 5-6㎎, divided into 3-4 doses. To discontinue treatment, reduce the dose by no more than 0.5㎎, usually at 3-day intervals; an even lower dose reduction may be required.

Precautions

This medication is a benzodiazepine that acts on the central nervous system and is used for sedation and anxiety relief. Taking this drug with narcotic substances may cause respiratory depression or severe sedation; therefore, it must be used only under the guidance of a physician at the minimum dosage and for the shortest duration possible. This medication carries a risk of dependency and abuse, so close monitoring and proper management by healthcare professionals are necessary during its use. Patients with hypersensitivity, certain ophthalmic diseases, severe myasthenia gravis, or severe liver or kidney dysfunction should not use this medication. Patients with heart disease or respiratory problems, the elderly, and those with decreased liver or kidney function should take it cautiously, and care should be taken in the case of allergic reactions. Drowsiness or decreased concentration may occur while taking this medication, so driving and operating hazardous machinery should be avoided. Long-term use may require regular blood tests and liver function tests, and abrupt discontinuation may trigger withdrawal symptoms or seizures, so tapering off gradually is necessary. Pregnant women in late pregnancy or those breastfeeding should avoid taking this medication, and dosage adjustments and careful administration are required for children and the elderly. Interactions may occur when taken with other central nervous system depressants, alcohol, certain antibiotics, and antifungal agents, so patients must inform their healthcare provider of other medications they are taking. In case of overdose, serious symptoms such as drowsiness, coma, and respiratory depression may occur, so immediate contact with a medical institution is necessary. This medication should be stored out of reach of children and kept in its original container to prevent misuse.

Side effects

  • Mild discomfort
  • insomnia
  • abdominal and muscle spasms
  • vomiting
  • sweating
  • tremors
  • seizures
  • agitation
  • increased muscle rigidity
  • sleep disturbances
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  • hallucinations
  • anxiety
  • anger
  • irritability
  • aggressive behavior
  • hostile behavior
  • hypersensitivity
  • hostility
  • obsessive thoughts
  • drowsiness
  • headache
  • depression
  • confusion
  • disorientation
  • decreased libido
  • anxiety
  • neurosthenia
  • increased libido
  • mania
  • hallucinations
  • anger
  • anxiety
  • drug dependence
  • hypomania
  • aggression
  • hostility
  • abnormal thinking
  • movement disorders
  • drug abuse
  • sedation
  • drowsiness
  • ataxia
  • memory impairment
  • dysphonia
  • dizziness
  • balance disorders
  • coordination disorders
  • attention disorders
  • hypersomnia
  • somnolence
  • tremors
  • amnesia
  • autonomic nervous system imbalance
  • muscle tone abnormalities
  • blurred vision
  • constipation
  • dry mouth
  • nausea
  • hepatitis
  • liver dysfunction
  • jaundice
  • dermatitis
  • angioedema
  • photosensitivity reactions
  • muscle weakness
  • urinary incontinence
  • urinary retention
  • sexual dysfunction
  • irregular menstruation
  • fatigue
  • drug withdrawal syndrome
  • peripheral edema
  • weight loss
  • weight gain
  • increased intraocular pressure
  • drowsiness
  • mild headache
  • depression
  • headache
  • confusion
  • insomnia
  • neurosthenia
  • syncope
  • dizziness
  • inability to sit still
  • thirst
  • constipation
  • diarrhea
  • nausea
  • increased salivation
  • tachycardia
  • palpitations
  • hypotension
  • blurred vision
  • excitement
  • tremors
  • dermatitis
  • nasal congestion
  • weight gain
  • weight loss
  • fatigue
  • motor coordination disorders
  • memory impairment
  • involuntary movement disorders
  • decreased libido
  • confused state
  • muscle isolated contraction
  • increased libido
  • changes in libido
  • weakness
  • abnormal muscle tone
  • syncope
  • inability to sit still
  • anxiety
  • disinhibition
  • sensory abnormalities
  • polyuria
  • vasomotor disorders
  • unreality
  • abnormal dreams
  • fear
  • warm sensation
  • decreased salivation
  • abdominal discomfort
  • chest pain
  • hyperventilation
  • upper respiratory infection
  • tinnitus
  • muscle cramps
  • muscle stiffness
  • sweating
  • rash
  • increased appetite
  • decreased appetite
  • urination disorders
  • menstrual disorders
  • erectile dysfunction
  • edema
  • urinary incontinence
  • infection
  • seizures
  • hallucinations
  • depersonalization
  • taste changes
  • double vision
  • increased bilirubin
  • increased liver enzymes
  • jaundice
  • delirium
  • apathy
  • hyperactivity
  • dyspepsia
  • asthenia
  • chest pain
  • lethargy
  • falls
  • drowsiness
  • decreased attention
  • decreased concentration
  • decreased reflexes
  • ataxia
  • excessive sedation
  • insomnia
  • anxiety
  • irritability
  • cognitive disorders
  • confused state
  • drug withdrawal syndrome
  • coma
  • respiratory depression

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air from entering, at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the efficacy of the medication.

Appearance and packaging

Appearance

Orange round tablets

Package unit

30 tablets/bottle, 200 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.