Medication info

Withers Pyroxicam Injection

Prescription medicationInjections
Ingredient · strength
Piroxicam›20mg / 1 ampoule
Manufacturer / importer
Withers Pharmaceuticals Co., Ltd.
Appearance
A brown ampoule containing a light yellow liquid injection
Packaging
50 ampoules/box [1mL x 50 ampoules]
Approval status
Active

MFDS item code 199302453 · Notified 1993.06.07 · Insurance code 660701401

Summary

Main use
Relief of chronic pain (back pain, etc.) and joint disorders (rheumatoid arthritis, etc.)
Who uses it
Adults
Adult dosage
(Oral) Adults: Take 20 mg of piroxicam orally once daily. The maximum recommended daily dose is 20 mg of piroxicam. To reduce the risk of adverse reactions, use the minimum effective dose for the shortest duration. The therapeutic effect and tolerability of this medicine should be reviewed within 14 days after starting treatment. If continued treatment is considered necessary, reviews should be more frequent. (Injection) Adults: Inject 20 mg of piroxicam intramuscularly once daily. The maximum recommended daily dose is 20 mg of piroxicam. To reduce the risk of adverse reactions, use the minimum effective dose for the shortest duration. The therapeutic effect and tolerability of this medicine should be reviewed within 14 days after starting treatment. If continued treatment is considered necessary, reviews should be more frequent. The oral or suppository form of this medicine may be used concomitantly; however, the total amount administered by both routes must not exceed the maximum recommended daily dose.

Ingredients

Manufacturer
Withers Pharmaceuticals Co., Ltd.

Efficacy & effects

Relief of chronic pain (back pain, etc.) and joint disorders (rheumatoid arthritis, etc.)

  • Rheumatoid arthritis
  • osteoarthritis
  • ankylosing spondylitis
  • low back pain
  • periarthritis of the shoulder
  • adhesive capsulitis
View approved original text

This medication is used only when other non-steroidal anti-inflammatory drugs are ineffective or insufficient. It is primarily prescribed for chronic joint diseases such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is also used for chronic inflammatory musculoskeletal diseases such as chronic low back pain, periarthritis of the shoulder, and adhesive capsulitis. In these cases, this medication helps alleviate symptoms and reduce inflammation. Therefore, this medication is recommended for those who do not respond to existing treatments. This medication is used in the treatment of chronic inflammatory diseases.

Dosage and Administration

Adult dosage

(Oral) Adults: Take 20 mg of piroxicam orally once daily. The maximum recommended daily dose is 20 mg of piroxicam. To reduce the risk of adverse reactions, use the minimum effective dose for the shortest duration. The therapeutic effect and tolerability of this medicine should be reviewed within 14 days after starting treatment. If continued treatment is considered necessary, reviews should be more frequent. (Injection) Adults: Inject 20 mg of piroxicam intramuscularly once daily. The maximum recommended daily dose is 20 mg of piroxicam. To reduce the risk of adverse reactions, use the minimum effective dose for the shortest duration. The therapeutic effect and tolerability of this medicine should be reviewed within 14 days after starting treatment. If continued treatment is considered necessary, reviews should be more frequent. The oral or suppository form of this medicine may be used concomitantly; however, the total amount administered by both routes must not exceed the maximum recommended daily dose.

Precautions

This medication may cause gastrointestinal bleeding in individuals who regularly consume more than three alcoholic beverages per day; therefore, consultation with a doctor or pharmacist is essential before use. This medication can affect the cardiovascular system and may increase the risk of myocardial infarction or stroke, requiring increased caution, especially for patients with cardiovascular diseases or risk factors. Severe gastrointestinal side effects such as gastrointestinal bleeding, ulcers, or perforations may occur, so elderly patients or those with a history of gastrointestinal diseases should use it cautiously. Fatal skin adverse reactions may occur; therefore, immediate discontinuation is necessary if skin rashes or hypersensitivity symptoms develop. Benzyl alcohol contained in this medication can cause life-threatening respiratory symptoms in premature infants, so products containing benzyl alcohol should be used with caution. When using injections, care must be taken to avoid glass contamination by carefully breaking the container, particularly when using it for children or elderly patients. Patients with a history of gastrointestinal ulcers, bleeding, perforation, severe liver dysfunction, kidney dysfunction, heart failure, hypertension, and similar conditions should not use this medication. Patients with peptic ulcers, hematologic abnormalities, liver dysfunction, kidney dysfunction, heart failure, hypertension, hypersensitivity, asthma, elderly patients, and those with a tendency to bleed should use this medication cautiously. This medication may cause various side effects such as dyspepsia, nausea, vomiting, diarrhea, skin rashes, anemia, hypertension, hepatitis, renal failure, etc., so any abnormal symptoms should be promptly reported to medical personnel. Long-term use requires regular blood tests and liver and kidney function tests, and it should be used with appropriate antibiotics in case of infectious diseases. This medication may prolong bleeding time, so patients at risk of bleeding should be cautious. It should not be taken in conjunction with other non-steroidal anti-inflammatory drugs, and interactions may occur when taken with specific medications; therefore, any ongoing medications should be disclosed. This medication should not be used during pregnancy, particularly in the late stages, as it may pose risks to the fetus, and nursing mothers are also advised against taking this medication. This medication should not be administered to children or those aged 80 years and older, and in elderly patients, it should be used cautiously at minimal doses. In the case of overdose, symptoms such as drowsiness, nausea, vomiting, and gastrointestinal bleeding may occur; immediate medical attention is necessary for appropriate treatment. This medication should be stored out of reach of children, and it is safer not to change the container.

Side effects

Peptic ulcer, hematemesis, hematochezia, gastrointestinal bleeding, epigastric pain, discomfort in the upper abdomen, loss of appetite, nausea, vomiting, diarrhea, loose stools, stomatitis, dyspepsia, abdominal bloating, constipation, glossitis, shock, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), Stevens-Johnson syndrome, Lyell syndrome, photosensitivity reaction, nail shedding, abnormal growth of toenails, hair loss, vesicular reaction, anemia, granulocytopenia, thrombocytopenia, aplastic anemia, bone marrow suppression, purpura, leukopenia, pancytopenia, eosinophilia, hypertension, congestive heart failure, acute cardiac disease, jaundice, hepatitis, elevated AST/ALT, elevated ALP, elevated LDH, acute renal failure, fluid retention, oliguria, hematuria, proteinuria, elevated BUN, elevated serum creatinine, hyperkalemia, rash, itching, bronchospasm, urticaria, angioedema, vasculitis, serum sickness, drowsiness, dizziness, headache, tinnitus, paresthesia in hands and feet, depression, irritability, hallucinations, mood changes, mental confusion, allergic edema of the face and hands, thirst, systemic fatigue, blurred vision, eye irritation, shoulder stiffness, fever, palpitations, dyspnea

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to light and should be stored in a container that can block light. It is also recommended to store the medication at room temperature, between 1 to 30 degrees Celsius, to maintain its effectiveness for a longer period.

Appearance and packaging

Appearance

A brown ampoule containing a light yellow liquid injection

Package unit

50 ampoules/box [1mL x 50 ampoules]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.