Pumatifen Tablets (Ketotifen Fumarate)

Adult dose

For adults, administer 1 mg of Ketotifen orally, twice daily (morning and evening meals). For those over 10 years old, a dose of up to 2 mg may be given if necessary. Begin the first week of treatment with 0.5 mg twice daily or 1 mg at bedtime, gradually increasing to 2 mg per day. Adjust according to age and symptoms.

Child dose

For children over 3 years old, administer 1 mg of Ketotifen orally, twice daily (morning and evening meals).

This medication should not be used in certain patients. Do not take this medication if you have had an allergy or hypersensitivity to this medicine or its ingredients in the past. Caution is advised for patients with convulsive disorders such as epilepsy, as this medication may induce seizures. This medication cannot replace corticosteroids used in asthma treatment and should not be used solely as an asthma therapy. Women who are breastfeeding should refrain from taking this medication, and if unavoidable, should stop breastfeeding. Patients taking oral hypoglycemic agents should be cautious as this medication may reduce platelet counts when used together. Patients with genetic metabolic disorders such as fructose intolerance should not take this medication due to certain ingredients in some formulations. This medication contains lactose, so individuals with a genetic disorder that reduces lactose breakdown ability should not take it. When administering this medication, caution must be taken not to abruptly discontinue existing medications in patients receiving asthma treatment. Patients who are steroid-dependent should gradually reduce their dosage to avoid adrenal insufficiency. Additionally, patients with allergy to the ingredient Yellow No. 5 contained in this medication should take it with caution. Taking this medication may cause side effects such as drowsiness, dizziness, dry mouth, excitement, and insomnia. Especially in children, central nervous system symptoms like excitation, irritability, and insomnia may occur more frequently, necessitating observation. Rare side effects such as severe skin reactions or liver function abnormalities have also been reported. When taking this medication for the first time, caution should be exercised during operation of machinery or driving as reaction time may be slower. If a patient has been on long-term steroid treatment, caution is needed to avoid adrenal insufficiency when changing or tapering off to this medication. If accompanied by infections, appropriate antibacterial treatment should be instituted. This medication does not suppress already occurring seizures, and this should be clearly communicated to the patient. Seasonal allergy patients are advised to start taking the medication prior to a worsening of symptoms and to continue until symptoms resolve. When discontinuing the medication, it should be gradually reduced over 2-4 weeks to minimize side effects. This medication may reduce platelet counts when taken with hypoglycemic agents, so blood tests should be conducted to monitor this. Additionally, when taken with sedatives, sleep aids, antihistamines, or alcohol, their effects may become more potent, necessitating dose adjustments. Food intake does not affect the absorption of this medication. The safety of this medication during pregnancy is not well established, so it should only be taken when absolutely necessary. Women who are breastfeeding should preferably not take this medication, as it may be secreted in breast milk, and if unavoidable, should discontinue breastfeeding. Children and infants may experience central nervous system symptoms such as seizures or excitation, so careful observation during administration is required. Dosing in children may differ from adults depending on weight, so guidelines from a healthcare professional should be followed. Elderly patients do not require significant dose adjustments, but caution is advised as their physiological function may be impaired. In cases of overdose, symptoms such as drowsiness, confusion, headache, severe sedation, seizures, and respiratory depression may occur, necessitating immediate medical attention. If seizures occur, prompt drug treatment and monitoring of cardiac function is required. This medication may interfere with allergy skin reaction tests, so it is advisable to discontinue use for at least 3-5 days prior to testing. This medication should be kept out of reach of children and stored in its original container to maintain quality.

Serious side effects

• Erythema multiforme
• Stevens-Johnson syndrome
• severe skin reactions
• hepatitis
• elevated liver enzymes
• seizures

Mild side effects

• Sedation
• dry mouth
• dizziness
• excitement
• irritability
• insomnia
• nervousness
• cystitis
• weight gain
• drowsiness

This medication should be stored in a tightly sealed container to prevent air from entering, and it is best to keep it at room temperature, avoiding extreme heat or cold. This will help maintain the efficacy of the medication for a longer period.

Appearance

Light yellowish-brown round tablets

Package unit

30 tablets/bottle, 100 tablets/bottle, 300 tablets/bottle