Codipin 8 mg (Benidipine Hydrochloride)

Adult dose

○ Adults Hypertension: Administer 2 ～ 4 mg of benidipine hydrochloride orally once daily after breakfast. If the effect is insufficient, the dose may be increased to 8 mg once daily. However, for severe hypertension, administer 4 ～ 8 mg orally once daily after breakfast. Angina: Administer 4 mg of this drug orally twice daily, after breakfast and dinner. Adjust the dose appropriately according to symptoms.

This drug should not be used in patients with cardiogenic shock, women who are pregnant or could become pregnant, individuals who are breastfeeding, or in children. Use with caution in patients with excessively low blood pressure, severe liver dysfunction, and in the elderly. Liver function abnormalities may occur, so if liver enzyme levels rise or jaundice symptoms appear, discontinue use immediately and monitor. It may also affect kidney function, so elevate the blood urea nitrogen or creatinine levels may require attention during blood tests. Blood-related adverse reactions such as leukopenia or thrombocytopenia may occur, so blood status should be checked regularly. Symptoms such as cardiac arrhythmias, facial flushing, warmth, and decreased blood pressure may occur, and if these symptoms appear, consult with a healthcare professional. Nervous system symptoms such as headaches, dizziness, and drowsiness may occur, so caution is advised when driving or operating dangerous machinery. Gastrointestinal symptoms such as constipation, nausea, and abdominal discomfort may also occur, and if discomfort persists, report it. Hypersensitivity reactions such as rash, itching, and photosensitivity reactions may occur, so discontinue use if such reactions arise. There may be various side effects such as swelling of the face, hands, or legs, lethargy, tinnitus, warmth in the hands and feet, so report any abnormal symptoms immediately. Abrupt discontinuation of this medication may worsen symptoms, so doses should be gradually reduced under medical guidance. There is a risk of temporary fainting due to excessive blood pressure reduction, so seek appropriate measures if symptoms arise. Caution is needed when using with other antihypertensive agents as the effect may be potentiated. Taking certain medications or grapefruit juice with this drug may lead to excessively low blood pressure, so do not take them together. Pregnant or breastfeeding women should avoid this drug, and if it must be used, breastfeeding should be discontinued. Safety in pediatric patients has not been established, so it is advisable not to use this medication in children. Elderly patients should start with a low dose to prevent excessive lowering of blood pressure and should be administered cautiously. In cases of overdose, severe blood pressure reduction may occur, requiring immediate medical attention, and this drug is not removed by dialysis. This medication should be taken strictly according to a doctor's instructions, and should not be discontinued or re-dosed arbitrarily. Patients undergoing chronic ambulatory peritoneal dialysis (CAPD) may present symptoms that need to be differentiated from peritonitis, so caution is necessary.

• Abnormal liver function
• jaundice
• increased BUN
• increased creatinine
• leukopenia
• eosinophilia
• thrombocytopenia
• palpitations
• facial flushing
• heat sensation

This medication should be stored in a sealed container to prevent air or moisture exposure, and it is recommended to keep it away from direct sunlight and at room temperature. Doing so will help maintain the effectiveness of the drug for a longer period.

Appearance

This medication is a yellow, round film-coated tablet.

Package unit

30 tablets/bottle, 300 tablets/bottle