Cordipin Tablets 4mg (Benidipine Hydrochloride)

Adult dose

Hypertension: Administer 2 ～ 4 mg of benidipine hydrochloride orally once daily after breakfast. If the effect is insufficient, the dose may be increased to 8 mg once daily. However, for severe hypertension, administer 4 ～ 8 mg orally once daily after breakfast. Angina: Administer 4 mg of this drug orally twice daily, after breakfast and dinner. Adjust the dose appropriately according to symptoms.

This medicine should not be used in patients with cardiogenic shock, in women who are pregnant or nursing, and in children. Caution should be taken when administering to patients with excessively low blood pressure, severe liver dysfunction, and elderly patients. Liver function should be closely monitored as liver function abnormalities may occur, and the medication should be discontinued immediately if abnormalities are found. Since it may also affect kidney function, renal-related values should be checked regularly. Blood tests may be required as blood-related adverse reactions such as leukopenia or thrombocytopenia may occur. Heart rhythm may become irregular or symptoms of excessively low blood pressure may appear, so heart conditions should be monitored carefully. Neurological symptoms such as headaches, dizziness, and drowsiness may occur, so caution is advised when driving or operating hazardous machinery. Gastrointestinal symptoms such as constipation, nausea, and vomiting may occur, and if discomfort persists, it should be reported. Allergic reactions such as rashes or itching may occur, so skin conditions should be checked, and administration should be stopped if abnormal symptoms are observed. Swelling may occur in the face, hands, or legs, so symptoms of edema should be observed carefully. This medicine may enhance the effect when used with other antihypertensive agents, so all medications being taken must be disclosed. Particularly, when used with digoxin, cimetidine, rifampicin, grapefruit juice, or itraconazole, caution should be exercised as blood pressure reduction or changes in effectiveness may occur. Women who are pregnant or may become pregnant should not take this medication, and nursing mothers should also avoid it if possible. Elderly patients should start with a low dose and be administered carefully to prevent excessive blood pressure reduction. Discontinuing the medication suddenly may worsen symptoms, so the dosage should be gradually reduced under a physician's direction. In the event of overdose, blood pressure may drop excessively, so medical personnel should be notified immediately, and appropriate treatment should be received. This medicine must be used strictly according to a doctor's prescription and instructions, and should not be stopped or altered arbitrarily.

• Liver dysfunction
• jaundice
• elevation of BUN
• elevation of creatinine
• leukopenia
• eosinophilia
• thrombocytopenia
• palpitations
• facial flushing
• warmth sensation

This medicine should be stored in a tightly closed container to protect it from air, and it is recommended to store it at room temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain its effectiveness and prevent degradation.

Appearance

This medicine is a yellow round film-coated tablet.

Package unit

30 tablets/bottle, 300 tablets/bottle