Medication info
Alprazolam 0.4 mg Tablet (Alprazolam)

Alprazolam 0.4 mg Tablet (Alprazolam)

Prescription medicationTabletOral
Ingredient · strength
Alprazolam›0.4mg / 1 tablet
Manufacturer / importer
Hwa In Pharmaceutical Co., Ltd.
Appearance
Orange round tablet
Packaging
30 tablets/bottle, 200 tablets/bottle
Approval status
Active

MFDS item code 199203462 · Approved 1992.03.10 · Insurance code 657200480

Summary

Main use
Relief of symptoms of anxiety disorders, anxiety accompanying depression, panic disorder, and psychosomatic disorders
Who takes it
Adults
Adult dose
Determine the dose individually to achieve maximum benefit. The usual daily doses listed below are suitable for most patients, although higher doses may be required. In such cases, increase the dose slowly to avoid adverse effects. The risk of dependence may increase with the dose and duration of treatment. Therefore, use the lowest effective dose for the shortest possible duration and frequently reassess the need to continue treatment. ○ Adults 1. As alprazolam, the initial dose is 0.25-0.5㎎ per dose, 3 times daily, with a maximum dose of 4㎎ daily. For older adults, patients with hepatic impairment, and debilitated patients, the initial dose is 0.25㎎ per dose, 2-3 times daily. Reduce the dose if adverse effects occur at the initial dose. 2. Psychosomatic disorders Administer this medicine orally at 1.2㎎ daily in 3 divided doses. If increasing the dose, increase it gradually to a maximum of 2.4㎎ daily and administer orally in 3-4 divided doses. For older adults, the initial dose is 0.4㎎ per dose, 1-2 times daily, with a maximum dose of 1.2㎎ daily. 3. Panic disorder Start with 0.5㎎ of this medicine and, depending on the patient's response, increase the dose by no more than 1㎎ at intervals of 3-4 days, to an average daily dose of 5-6㎎ divided into 3-4 doses. When discontinuing treatment, reduce the dose by no more than 0.5㎎, usually at intervals of 3 days; an even lower dose reduction may be required.

Ingredients

Manufacturer
Hwa In Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of symptoms of anxiety disorders, anxiety accompanying depression, panic disorder, and psychosomatic disorders

  • Anxiety disorders
  • anxiety symptoms
  • anxiety accompanying depression
  • anxiety in psychosomatic disorders
  • tension
  • depression
  • sleep disturbances
  • panic disorder
View approved original text

This medication is used for the treatment of anxiety disorders and for the short-term relief of anxiety symptoms. It also alleviates anxiety accompanying depression and reduces symptoms of anxiety, tension, depression, and sleep disturbances that occur in psychosomatic disorders related to the gastrointestinal and colon. It is effective in managing symptoms of panic disorder. Therefore, this medication helps to improve various anxiety-related conditions.

How to take

Adult dose

Determine the dose individually to achieve maximum benefit. The usual daily doses listed below are suitable for most patients, although higher doses may be required. In such cases, increase the dose slowly to avoid adverse effects. The risk of dependence may increase with the dose and duration of treatment. Therefore, use the lowest effective dose for the shortest possible duration and frequently reassess the need to continue treatment. ○ Adults 1. As alprazolam, the initial dose is 0.25-0.5㎎ per dose, 3 times daily, with a maximum dose of 4㎎ daily. For older adults, patients with hepatic impairment, and debilitated patients, the initial dose is 0.25㎎ per dose, 2-3 times daily. Reduce the dose if adverse effects occur at the initial dose. 2. Psychosomatic disorders Administer this medicine orally at 1.2㎎ daily in 3 divided doses. If increasing the dose, increase it gradually to a maximum of 2.4㎎ daily and administer orally in 3-4 divided doses. For older adults, the initial dose is 0.4㎎ per dose, 1-2 times daily, with a maximum dose of 1.2㎎ daily. 3. Panic disorder Start with 0.5㎎ of this medicine and, depending on the patient's response, increase the dose by no more than 1㎎ at intervals of 3-4 days, to an average daily dose of 5-6㎎ divided into 3-4 doses. When discontinuing treatment, reduce the dose by no more than 0.5㎎, usually at intervals of 3 days; an even lower dose reduction may be required.

Precautions

This medication can cause severe drowsiness or respiratory cessation if taken with narcotics, so it should only be used at the minimum effective dose and duration when absolutely necessary. This medication can be habit-forming, so patients taking it should be carefully monitored as per the physician's instructions, and any remaining medication should be stored and disposed of safely to prevent misuse. This medication should not be administered to patients with certain conditions or those taking certain medications, especially those who are at risk, such as patients with acute angle-closure glaucoma, severe myasthenia gravis, severe respiratory failure, and severe liver failure. Caution should be exercised when using this medication in individuals with heart, liver, kidney problems, elderly patients, frail patients, or those with respiratory diseases. Use of this medication may lead to drowsiness, decreased concentration, and reduced motor skills, so it is advisable to avoid driving or operating hazardous machinery. If used for an extended period, regular blood tests and liver function tests should be conducted, and abrupt discontinuation can lead to withdrawal symptoms or seizures, so the dosage should be tapered off gradually. This medication should be used with caution in patients with depression, as it can sometimes cause sudden mood changes or aggressive behavior. This medication may increase the effects of other central nervous system depressants, alcohol, and narcotic analgesics, leading to serious side effects; therefore, concomitant use should be avoided or discussed with a physician. During pregnancy, especially in the last three months, this medication should not be taken; while breastfeeding, caution is necessary as it can be excreted in breast milk affecting the baby. It is advisable to avoid use in children and adolescents under the age of 18, as safety and efficacy have not been established. In the event of overdose, symptoms such as severe drowsiness, coma, and respiratory distress may occur, and immediate medical attention should be sought for appropriate treatment. This medication should be kept out of reach of children and stored in the original container to prevent misuse or degradation.

Side effects

  • Mild discomfort
  • insomnia
  • abdominal and muscle cramps
  • vomiting
  • sweating
  • tremors
  • seizures
  • agitation
  • increased muscle rigidity
  • sleep disturbances
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  • hallucinations
  • anxiety
  • anger
  • irritability
  • aggressive behavior
  • hostile behavior
  • hypersensitivity
  • hostility
  • obsessive thinking
  • drowsiness
  • headache
  • depression
  • confusion
  • disorientation
  • decreased libido
  • anxiety
  • nervousness
  • increased libido
  • mania
  • anger
  • restlessness
  • drug dependence
  • hypomania
  • aggression
  • hostility
  • abnormal thinking
  • movement disorders
  • drug abuse
  • ataxia
  • memory impairment
  • dysarthria
  • dizziness
  • balance disorders
  • cooperation disorders
  • attention deficit
  • hypersomnia
  • narcolepsy
  • tremors
  • amnesia
  • autonomic nervous system imbalance
  • muscle tone abnormalities
  • blurred vision
  • constipation
  • dry mouth
  • nausea
  • gastrointestinal disturbances
  • hepatitis
  • liver dysfunction
  • jaundice
  • dermatitis
  • angioedema
  • photosensitivity reactions
  • muscle weakness
  • urinary incontinence
  • urinary retention
  • sexual dysfunction
  • irregular menstruation
  • fatigue
  • drug withdrawal syndrome
  • peripheral edema
  • weight loss
  • weight gain
  • increased intraocular pressure
  • drowsiness
  • mild headache
  • depression
  • headache
  • confusion
  • insomnia
  • nervousness
  • fainting
  • dizziness
  • inability to sit still
  • thirst
  • diarrhea
  • increased salivation
  • tachycardia
  • palpitations
  • hypotension
  • nasal congestion
  • constipation
  • tremors
  • dermatitis
  • rash
  • increased appetite
  • decreased appetite
  • urinary disorders
  • menstrual disorders
  • erectile dysfunction
  • edema
  • urinary incontinence
  • infection
  • hallucinations
  • depersonalization
  • taste changes
  • double vision
  • increased bilirubin
  • elevated liver enzymes
  • jaundice
  • involuntary movements
  • disinhibition
  • sensory disturbances
  • hypersalivation
  • vasomotor disorders
  • derealization
  • abnormal dreams
  • fear
  • warm sensation
  • decreased salivation
  • abdominal discomfort
  • chest pain
  • hyperventilation
  • upper respiratory infection
  • tinnitus
  • muscle cramps
  • muscle rigidity
  • sweating
  • weight gain
  • weight loss
  • urinary disorders
  • menstrual disorders
  • erectile dysfunction
  • edema
  • urinary incontinence
  • infection
  • delirium
  • apathy
  • hyperactivity
  • dyspepsia
  • asthenia
  • chest pain
  • lethargy
  • falls
  • coordination disorders
  • incoherent speech
  • coma
  • respiratory depression

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent air or moisture from entering, away from direct sunlight, and at room temperature. This way, its effectiveness can be maintained for a long duration and deterioration can be prevented.

Appearance and packaging

Appearance

Orange round tablet

Package unit

30 tablets/bottle, 200 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.