Question 1

What are the indications and effects of Oktasin Tablet (Ofloxacin)?

Accepted Answer

This medication is an antibiotic effective against various bacteria, used for infections caused by different types of bacteria including staphylococcus, streptococcus, and Escherichia coli. It is effective for complicated skin and soft tissue infections, acute and chronic otitis media, sinusitis, pneumonia, and acute exacerbations of chronic obstructive pulmonary disease. Additionally, it is used to treat bacterial infections in various areas including acute pyelonephritis, cystitis, prostatitis, urethritis, enteritis, endometritis, and eye-related infections. However, this drug should only be used when other treatment options are unavailable due to the possibility of significant adverse reactions. It is important to consult with a specialist based on the patient's symptoms and medical history. This medication helps treat complicated bacterial infections.

Question 2

What are the dosage and administration instructions for Oktasin Tablet (Ofloxacin)?

Accepted Answer

Adults: The usual dose is 300～600 mg of ofloxacin per day, divided into 2～3 doses.
For Hansen’s disease, the dose is 400～600 mg of this medicine per day, divided into 2～3 doses. In principle, it should be used in combination with other anti-leprosy drugs.
The dose may be adjusted appropriately according to age and symptoms.

Question 3

What are the side effects of Oktasin Tablet (Ofloxacin)?

Accepted Answer

Tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects, exacerbation of myasthenia gravis, anaphylactic shock, anaphylactic reactions, rash, itching, erythema, edema, fever, warmth, blisters, erythema, photosensitivity reactions, hematuria, acute renal failure, nephrolithiasis, interstitial nephritis, elevated BUN, elevated serum creatinine, jaundice, liver failure, elevated AST/ALT, elevated ALP, elevated γ-GTP, elevated total bilirubin, cholestatic jaundice, fulminant hepatitis, pseudomembranous colitis, abdominal pain, frequent diarrhea, nausea, vomiting, gastrointestinal discomfort, diarrhea, cirrhosis, anorexia, abdominal pain, dyspepsia, chest pain, thirst, taste disturbances, stomatitis, glossitis, abdominal distention, constipation, dysphagia, gastrointestinal bleeding, oral mucosal pain, intestinal perforation, anemia, leukopenia, decreased hemoglobin, decreased hematocrit, thrombocytopenia, eosinophilia, agranulocytosis, thrombotic thrombocytopenic purpura, petechial and ecchymotic bleeding, prolonged prothrombin time, reversible bone marrow suppression, lymphopenia, neutropenia, increased ESR, insomnia, dizziness, headache, seizures, tremors, paresthesia, peripheral neuropathy, visual disturbances, auditory disturbances, hallucinations, drowsiness, nervousness, sleep disorders, confusion, anxiety, depression, agitation, delirium, seizures, nightmares, paranoia, disorientation, attention deficits, memory disorders, delirium, suicidal ideation, suicide, perceptual disturbances, olfactory and equilibrium disturbances, ataxia, aphasia, heaviness in the head, Stevens-Johnson syndrome, toxic epidermal necrolysis, arthralgia, myalgia, muscle weakness, myositis, fatigue, elevated CPK, elevated myoglobin, rhabdomyolysis, pharyngitis, dyspnea, bronchospasm, allergic pneumonia, epistaxis, stridor, fever, cough, abnormal chest X-ray, eosinophilia, interstitial pneumonia, cerebral thrombosis, pulmonary edema, tachycardia, hypertension, hypotension, palpitations, vasodilation, circulatory collapse, prolonged QT interval, ventricular tachycardia, dysuria, increased urination, urinary retention, anuria, polyuria, hematuria, storage urine, pyuria, diabetes, proteinuria, alkaline urine, vaginitis, vaginal candidiasis, increased vaginal discharge, itching of the female external genitalia, menstrual irregularities, uterine cramps, genital rashes in females, pain, irritation, burning sensation, hypoglycemic symptoms, limb pain, malaise, fever, aortic aneurysm, aortic dissection, heart valve regurgitation, heart valve insufficiency, drowsiness, nausea, facial flushing, facial edema, paresthesia, inaccurate pronunciation, loss of sense of direction

Question 4

What precautions should be taken when using Oktasin Tablet (Ofloxacin)?

Accepted Answer

This medication can cause serious side effects such as tendinitis or tendon rupture, and it should be discontinued immediately if such symptoms appear.

Additionally, this medication can lead to peripheral neuropathy and central nervous system adverse reactions, so caution should be taken if sensory abnormalities or neurological symptoms occur.

This medication should not be used in patients with myasthenia gravis as it may worsen symptoms.

This medication is restricted to specific bacterial infections, such as acute bacterial non-sinusitis, acute exacerbation of chronic bronchitis, uncomplicated urinary tract infections, and acute otitis media.

Elderly patients, those with kidney dysfunction, solid organ transplant recipients, and patients taking corticosteroids should avoid this medication due to an increased risk of tendon rupture when combined.

This medication can trigger seizures, so patients with a history of epilepsy or seizures should use it cautiously and discontinue immediately if seizures occur.

It should not be used in pregnant or potentially pregnant women, nursing mothers, or growing children and adolescents.

During treatment, patients should avoid strong sunlight or artificial ultraviolet exposure, and discontinue use if rash or photosensitivity reactions occur.

This medication can cause various side effects, including skin rash, impaired liver function, kidney problems, gastrointestinal disorders, blood disorders, central nervous system issues, and respiratory issues, so patients should consult a doctor if any abnormal symptoms arise.

Diabetic patients on blood sugar control should carefully monitor their blood sugar levels due to risks of hypoglycemia or hyperglycemia.

This medication may interact with other drugs, especially anticoagulants, certain anti-inflammatory medications, antihypertensives, and antacids, so it is important to consult a doctor when used in combination.

Patients should ensure sufficient fluid intake while taking this medication and avoid driving or operating dangerous machinery if experiencing dizziness or drowsiness.

In case of overdose, seek medical attention immediately, as this medication cannot be completely removed by hemodialysis.

Store in a location out of reach of children and do not transfer to another container for safety.

Oktasin Tablet (Ofloxacin)

Summary

Ingredients

Efficacy & effects

How to take

Adult dose

Precautions

Side effects

Storage

Appearance and packaging

Appearance

Package unit

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