Medication info
Prozac (Nabumetone)

Prozac (Nabumetone)

Prescription medicationTabletOral
Ingredient · strength
Nabumetone›500mg / 1 tablet
Manufacturer / importer
Chodang Pharmaceutical Co., Ltd.
Appearance
It is a white to yellowish-white round film-coated tablet.
Packaging
30, 500 tablets/bottle
Approval status
Active

MFDS item code 199202530 · Notified 1992.03.17 · Insurance code 670701170

Summary

Main use
Relief of pain and inflammation associated with arthritis (including osteoarthritis)
Who takes it
Adults · Children
Adult dose
This drug is for oral use. Swallow without chewing (tablets only). Adults: Administer 1 g of nabumetone orally once daily at bedtime. If symptoms are severe or persistent, or worsen rapidly, administer an additional 500 mg∼1 g orally in the morning. Older adults: As with many other drugs, plasma concentrations may be higher in older patients. Do not exceed a maximum of 1 g daily; in some cases, 500 mg may provide satisfactory symptom relief.
Child dose
There are no clinical data yet on the use of this product in children.

Ingredients

Manufacturer
Chodang Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of pain and inflammation associated with arthritis (including osteoarthritis)

  • Osteoarthritis
  • rheumatoid arthritis
View approved original text

This medication reduces inflammation and pain caused by arthritis, such as osteoarthritis and rheumatoid arthritis. It alleviates inflammation to decrease swelling and pain in the joints, making movement more comfortable. As a result of these effects, the daily lives of patients with arthritis are significantly improved. Therefore, it is used for the treatment of osteoarthritis and rheumatoid arthritis.

How to take

Adult dose

This drug is for oral use. Swallow without chewing (tablets only). Adults: Administer 1 g of nabumetone orally once daily at bedtime. If symptoms are severe or persistent, or worsen rapidly, administer an additional 500 mg∼1 g orally in the morning. Older adults: As with many other drugs, plasma concentrations may be higher in older patients. Do not exceed a maximum of 1 g daily; in some cases, 500 mg may provide satisfactory symptom relief.

Child dose

There are no clinical data yet on the use of this product in children.

Precautions

Individuals who regularly consume more than three cups of alcohol daily should consult a doctor or pharmacist before taking this medication, as there may be an increased risk of gastric bleeding when taken with alcohol. This medication can affect the cardiovascular system; therefore, patients with heart disease or risk factors should exercise special caution. There is an increased risk of cardiovascular problems such as myocardial infarction or stroke; symptoms should be reported to medical personnel immediately. This medication can burden the gastrointestinal tract, and there is a risk of serious gastrointestinal adverse reactions like gastric bleeding, ulcers, or perforation. Especially elderly patients or those with a history of gastrointestinal disorders should start with the minimum dosage and report any gastrointestinal symptoms immediately. Patients with peptic ulcers, severe blood disorders, liver impairment, renal impairment, heart impairment, or allergies to this medication or its components should not use it. Additionally, patients with aspirin-induced asthma or allergic reactions to aspirin and other non-steroidal anti-inflammatory drugs should not be administered this medication. Patients with blood disorders, liver impairment, kidney impairment, heart impairment, chronic airway diseases, allergic rhinitis, hypertension, heart failure, autoimmune diseases, etc., should use this medication with caution and require regular examinations. This medication can cause shock or severe allergic reactions; therefore, if any unusual symptoms occur, discontinue use immediately and seek appropriate treatment. Moreover, various side effects such as dyspepsia, abdominal pain, nausea, vomiting, diarrhea, headache, dizziness, liver dysfunction, kidney dysfunction, and skin rash may occur, so caution is necessary. Pregnant women or those who may become pregnant, and nursing mothers should not take this medication, as it may be harmful to the fetus, and there is a risk of adverse reactions in breastfeeding infants. This medication is not recommended for children or adolescents under the age of 15 as its safety has not been established. Elderly patients have a higher risk of gastrointestinal bleeding or perforation, so it is advisable to monitor them closely, especially during the first four weeks and to use the minimum dosage. Taking this medication in conjunction with other non-steroidal anti-inflammatory drugs may increase the risk of side effects; therefore, co-administration should be avoided, and consultation with a doctor is necessary when using it alongside blood pressure medications, diuretics, anticoagulants, etc. In case of overdose, symptoms such as headache, nausea, vomiting, gastric bleeding, and coma may appear, and immediate medical treatment should be sought. Finally, keep this medication out of reach of children and do not transfer it to other containers for safety.

Side effects

  • Shock
  • anaphylactic reaction symptoms
  • dyspnea
  • urticaria
  • hypotension
  • angioedema
  • facial swelling
  • rash
  • itching
  • dyspepsia
Show 98 more
  • abdominal pain
  • gastric discomfort
  • epigastric pain
  • abdominal distension
  • anorexia
  • nausea
  • vomiting
  • hematemesis
  • diarrhea
  • constipation
  • aerophagia
  • gastritis
  • peptic ulcer
  • perforation
  • gastrointestinal bleeding
  • gastrointestinal disorders
  • hematochezia
  • melena
  • ulcerative colitis
  • Crohn's disease onset or exacerbation
  • pancreatitis
  • stomatitis
  • xerostomia
  • dizziness
  • headache
  • confusion
  • fear
  • neurosensitization
  • hypertonia
  • insomnia
  • drowsiness
  • sensory disturbances
  • elevated AST
  • elevated ALT
  • elevated AL-P
  • liver failure
  • hepatitis
  • jaundice
  • nephrotic syndrome
  • renal failure
  • urinary disorders
  • interstitial nephritis
  • acute tubular necrosis
  • papillary necrosis
  • elevated urinary protein
  • elevated BUN
  • elevated serum creatinine
  • interstitial pneumonia
  • respiratory impairment
  • bronchospasm
  • asthma
  • epistaxis
  • vascular edema
  • pseudoporphyria
  • hair loss
  • erythema multiforme
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
  • sweating
  • photosensitivity reactions
  • thrombocytopenia
  • neutropenia
  • agranulocytosis
  • leukopenia
  • leukemia
  • aplastic anemia
  • hemolytic anemia
  • vasculitis
  • hypertension
  • heart failure
  • myopathy
  • neck stiffness
  • uterine bleeding
  • menorrhagia
  • tinnitus
  • ear disorders
  • abnormal vision
  • visual impairment
  • optic neuritis
  • edema
  • fatigue
  • weakness
  • aseptic meningitis
  • headache
  • nausea
  • vomiting
  • epigastric pain
  • gastrointestinal bleeding
  • diarrhea
  • disorientation
  • agitation
  • coma
  • dizziness
  • tinnitus
  • fainting
  • seizures
  • acute renal failure
  • liver damage

Not everyone experiences these, and they can vary from person to person.

Storage

This medication does not require special refrigeration and can be stored at room temperature. It should be kept away from direct sunlight and stored in a cool, dry place.

Appearance and packaging

Appearance

It is a white to yellowish-white round film-coated tablet.

Package unit

30, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.