Ciclo Tablet (Acyclovir)

Adult dosage

1. Treatment of simplex herpes virus infections: As Acyclovir, administer 200 mg every 4 hours for 5 days, five times a day; treatment may be extended in severe primary infections. 2. Prevention of simplex herpes infections in immunocompetent patients: Administer 200 mg approximately every 6 hours four times a day, or 400 mg every 12 hours twice a day. 3. Prevention of simplex herpes infections in immunocompromised patients: Administer 200 mg every 6 hours four times a day, or consider increasing doses to 400 mg per dose in severe immunocompromised patients (such as post-bone marrow transplant) or changing to parenteral administration due to gastrointestinal absorption issues.

Children's dosage

1. Treatment of simplex herpes infections and prevention in immunocompromised patients: - 2 years and older: Same as adults. - Under 2 years: Administer 1/2 of the adult dose. 2. Treatment of chickenpox in children over 2 years: Administer 20 mg per kg of body weight per dose (maximum 800 mg) 4 times a day for 5 days. Treatment is more effective when started soon after chickenpox lesions appear, preferably within 24 hours.

This drug contains acyclovir and should not be administered to certain patients. Patients who have had hypersensitivity to this drug or any of its components, or to valacyclovir, should not use it. Caution is required when administering to patients with impaired renal function as they are at higher risk of neurological adverse reactions. Patients with impaired liver function should be administered cautiously as liver function may deteriorate. In infants or children, it should be used minimally and only when necessary, and caution should be exercised for elderly patients as they may experience more side effects due to decreased renal function. During the use of this drug, it is possible to rarely experience anaphylactic shock or severe hypersensitivity reactions, so if symptoms like low blood pressure, difficulty breathing, or chest tightness occur, administration must be stopped immediately and medical personnel should be informed. Disorders such as rash, fever, blisters, hives, alopecia, severe skin diseases may occur, so if any unusual symptoms appear, stop use and seek appropriate treatment. Neurological effects can occur, leading to altered consciousness, confusion, hallucinations, convulsions, drowsiness, anxiety, and these symptoms may occur more frequently in elderly patients or those with impaired renal function. As it can burden the kidneys, careful monitoring for renal-related abnormal symptoms, such as renal failure or hematuria, should be conducted. Various side effects have been reported, including blood and lymphatic abnormalities, liver function abnormalities, gastrointestinal symptoms, musculoskeletal pain, cardiovascular issues, urinary problems, therefore, if symptoms occur, consult medical personnel immediately. This drug is most effective when administered early in the course of the illness, so it is important to start treatment as soon as symptoms appear. Maintain adequate hydration during the treatment period to reduce the risk of dehydration and renal toxicity. Caution is required for hazardous activities such as driving or operating machinery due to potential altered consciousness. Drug interactions may occur when taken with other medications, so be sure to inform medical personnel of any medications being taken. Pregnant women or those who may become pregnant should only take this drug if the benefits outweigh the risks, and breastfeeding must be suspended during treatment. In cases of overdose, severe neurological symptoms or kidney damage may occur, so immediate medical assistance should be sought, and procedures such as dialysis may be needed if necessary. High-dose administration of this drug may affect genetic abnormalities or reproductive function; however, no such effects have been reported within recommended dosages.

Serious side effects

Anaphylactic shock, anaphylaxis-like reactions, hypotension, difficulty breathing, chest tightness, urticaria, skin and mucosal syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell syndrome), jaundice, altered consciousness, seizures, drowsiness, tremors, coma, psychosis, encephalopathy, hallucinations, inability to walk, renal failure, severe rash with high fever, blisters, skin peeling, mouth/eye mucosal pain, significantly reduced urine output, generalized severe swelling

Mild side effects

• Photosensitivity reaction
• fixed drug eruption
• rash
• fever
• blisters
• hives-like erythema
• alopecia
• erythema multiforme
• altered consciousness
• disorientation

This drug is sensitive to light and should be stored in a container that blocks light. Additionally, to safely store the medication, it is recommended to keep it at room temperature, ideally not too hot or too cold.

Appearance

Light blue round tablets

Package unit

30 tablets/bottle, 100 tablets/bottle