Medication info
Handokrella Fenjeong (Nabumetone)

Handokrella Fenjeong (Nabumetone)

Prescription medicationTabletOral
Ingredient · strength
Nabumetone›500mg / 1 tablet
Manufacturer / importer
(Co., Ltd.) Handok
Appearance
Caramel-scented, dark red oblong film-coated tablet.
Packaging
100 tablets, 30 tablets/bottle
Approval status
Active

MFDS item code 199200885 · Notified 1992.10.13 · Insurance code 652101610

Summary

Main use
Relief of pain and inflammation associated with arthritis (such as osteoarthritis)
Who takes it
Adults · Children
Adult dose
Swallow this medicine without chewing (tablets only). Adults: Administer 1 g of nabumetone orally once daily at bedtime. If symptoms are severe or persistent, or worsen rapidly, administer an additional 500 mg∼1 g of this medicine orally in the morning. Elderly patients: As with many other medicines, blood concentrations may be higher in elderly patients. Do not exceed a maximum of 1 g per day; in some cases, satisfactory symptom relief may be achieved with a dose of 500 mg.
Child dose
Children: Clinical data on the use of this product in children are not yet available.

Ingredients

Manufacturer
(Co., Ltd.) Handok

Efficacy & effects

Relief of pain and inflammation associated with arthritis (such as osteoarthritis)

  • Osteoarthritis
  • rheumatoid arthritis
View approved original text

This medication reduces inflammation and pain caused by osteoarthritis and rheumatoid arthritis, alleviating symptoms. It helps relieve joint swelling and stiffness, thereby improving joint function. Additionally, it assists in maintaining joint movement during long-term treatment. With these effects, it enhances the quality of daily life for patients. Therefore, this medication is used to treat inflammation and pain in osteoarthritis and rheumatoid arthritis.

How to take

Adult dose

Swallow this medicine without chewing (tablets only). Adults: Administer 1 g of nabumetone orally once daily at bedtime. If symptoms are severe or persistent, or worsen rapidly, administer an additional 500 mg∼1 g of this medicine orally in the morning. Elderly patients: As with many other medicines, blood concentrations may be higher in elderly patients. Do not exceed a maximum of 1 g per day; in some cases, satisfactory symptom relief may be achieved with a dose of 500 mg.

Child dose

Children: Clinical data on the use of this product in children are not yet available.

Precautions

This medication should be used with caution by individuals who regularly consume more than three alcoholic beverages per day, as it may increase the risk of gastrointestinal bleeding; consultation with a doctor or pharmacist is essential. This medication may increase the risk of cardiovascular disease, so patients with a history of heart disease or stroke or those with risk factors should be particularly careful. During the course of this medication, cardiovascular symptoms should be carefully monitored; if symptoms arise, immediate consultation with medical personnel is advised. This medication can cause serious gastrointestinal adverse reactions such as gastrointestinal bleeding, ulcers, and perforations, so elderly patients or those with a history of gastrointestinal disease should be especially cautious. Patients with a history of gastrointestinal bleeding or ulcers should refrain from taking this medication, and dosages should be immediately stopped upon the appearance of gastrointestinal bleeding symptoms. This medication should not be administered to patients with peptic ulcers, severe liver disease, kidney disease, heart failure, drug hypersensitivity, or aspirin-sensitive asthma. Patients with chronic diseases, the elderly, or those with chronic kidney or liver disease should undergo regular monitoring of liver and kidney functions during treatment with this medication. This medication may cause severe allergic reactions, such as shock, anaphylaxis, severe skin reactions, or exacerbation of asthma; immediate discontinuation and treatment from medical personnel are required upon appearance of symptoms. Dizziness, drowsiness, or visual disturbances may occur during dosage; it is safer to avoid driving or handling dangerous machinery. Interactions may occur when taken concurrently with other non-steroidal anti-inflammatory drugs, anticoagulants, diuretics, lithium, methotrexate, etc., so consultation with medical personnel is necessary. Pregnant or potentially pregnant women and nursing mothers should not take this medication, especially during late pregnancy, as it may have serious effects on the fetus. Safety for children and adolescents under 15 years of age has not been established, so administration is not recommended. Elderly patients are at higher risk for gastrointestinal bleeding or perforation, so the minimum possible dose should be used, and symptoms of gastrointestinal bleeding should be closely monitored in the first four weeks of treatment. In the event of overdose, symptoms may include headache, nausea, vomiting, gastrointestinal bleeding, coma, etc.; if suspected, immediate medical attention should be sought for proper treatment. This medication should be kept out of reach of children and not transferred to other containers, as this is important for the safety and quality of the medication.

Side effects

  • Shock
  • symptoms resembling anaphylaxis
  • shortness of breath
  • hives
  • low blood pressure
  • angioedema
  • facial swelling
  • rash
  • itching
  • dyspepsia
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  • abdominal pain
  • upper abdominal discomfort
  • epigastric pain
  • abdominal distension
  • loss of appetite
  • nausea
  • vomiting
  • hematemesis
  • diarrhea
  • constipation
  • air in the gastrointestinal tract
  • gastritis
  • peptic ulcer
  • perforation
  • gastrointestinal bleeding
  • gastrointestinal disorders
  • hematochezia
  • melena
  • ulcerative colitis
  • onset or exacerbation of Crohn's disease
  • pancreatitis
  • stomatitis
  • dry mouth
  • dizziness
  • headache
  • confusion
  • fear
  • irritability
  • increased tension
  • insomnia
  • drowsiness
  • sensory abnormalities
  • elevated AST
  • elevated ALT
  • elevated AL-P
  • liver failure
  • hepatitis
  • jaundice
  • nephrotic syndrome
  • renal failure
  • urinary disorders
  • interstitial nephritis
  • acute tubular necrosis
  • papillary necrosis
  • elevated urinary protein
  • elevated BUN
  • elevated serum creatinine
  • interstitial pneumonia
  • respiratory distress
  • bronchospasm
  • asthma
  • nasal bleeding
  • vascular edema
  • pseudo porphyria
  • hair loss
  • polymorphic light eruption
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
  • sweating
  • photosensitivity reactions
  • thrombocytopenia
  • neutropenia
  • agranulocytosis
  • leukopenia
  • leukemia
  • aplastic anemia
  • hemolytic anemia
  • vasculitis
  • elevated blood pressure
  • heart failure
  • myopathy
  • neck stiffness
  • uterine bleeding
  • heavy menstruation
  • tinnitus
  • ear disorders
  • abnormal vision
  • visual impairment
  • optic neuritis
  • edema
  • fatigue
  • weakness
  • aseptic meningitis
  • headache
  • nausea
  • vomiting
  • gastrointestinal bleeding
  • diarrhea
  • disorientation
  • agitation
  • coma
  • dizziness
  • tinnitus
  • fainting
  • convulsions
  • acute renal failure
  • liver damage

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent air exposure, kept away from direct sunlight, and stored at room temperature. Room temperature typically refers to temperatures between 15 and 25 degrees Celsius, and extremes of heat or cold should be avoided.

Appearance and packaging

Appearance

Caramel-scented, dark red oblong film-coated tablet.

Package unit

100 tablets, 30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.