GC Wellbeing Aminoplex Injection

Adult dosage

As a total amino acid, intravenous drip administration should be done at a maximum of 1-1.5 g per kg of body weight per day. An infusion rate of 10 g of total amino acids over 60 minutes is desirable, with a target of 30-40 drops per minute.

Children's dosage

In children, the dosage and infusion rate should be adjusted accordingly.

This medication should be used under a doctor's direction. It should not be used in patients with hepatic coma or those at risk of hepatic coma. Patients with severely impaired kidney function or high blood urea nitrogen should not be administered this medication. Do not administer in patients with problems in nitrogen metabolism, severe heart failure, pulmonary edema, or very low or no urine output. If sodium or chloride ions are present, it is also contraindicated for patients with hypernatremia, hyperchloridemia, or alkalosis. In patients with severe acidosis, congestive heart failure, edema due to sodium retention, hyperkalemia or potassium retention, and hepatic or renal impairment, it should be used with caution. The sodium bisulfite included in this medication may cause allergic reactions, particularly increasing the risk of asthma attacks in asthmatic patients, warranting caution. If hypersensitivity reactions such as rashes occur during administration, use should be stopped immediately. Symptoms such as nausea, vomiting, chest discomfort, palpitations, rapid heartbeat, and increased blood pressure may occasionally occur. Rapid infusion in large doses can lead to acidosis, so caution is required. Other reported symptoms include chills, fever, headache, shortness of breath, shock, bronchospasm, and urinary tract spasms. Metabolic complications such as metabolic acidosis, hypophosphatemia, alkalosis, hyperglycemia, dehydration, hypoglycemia, elevated liver enzymes, vitamin imbalance, electrolyte abnormalities, and pediatric hyperammonemia may occur. In patients with impaired liver or kidney function, blood urea nitrogen (BUN) may increase, and patients with liver failure may exhibit blood amino acid imbalance, metabolic alkalosis, hyperammonemia, and consciousness disorders. Special care should be taken in maintaining electrolyte balance when administering large doses of this medication or using it with other electrolyte-containing solutions. Metabolic alkalosis may occur in overdose, so particular caution should be applied with preparations containing acetate ions. In patients with a history of kidney, lung, or heart disease, care must be taken to avoid excessive fluid overload. Blood glucose levels should be monitored closely when administering to diabetic patients. This medication may reduce protein-sparing effects when used with tetracycline-class drugs. The safety for pregnant women has not been established; it should only be administered when the therapeutic benefits outweigh the risks. In children, doses should be adjusted as liver function may be immature, and blood ammonia levels should be monitored frequently. Elderly patients may have reduced physiological capacity; thus, the infusion rate should be slow, and doses should be adjusted. As this medication contains electrolytes, special attention should be paid to maintaining electrolyte balance during large doses, and it should be administered via slow intravenous infusion. Rapid infusion may induce chills and vomiting and cause amino acid loss through the kidneys. It is advisable to warm the medication to body temperature before use and to prepare and handle it under aseptic conditions. The medication should not be used if discoloration, leaks, or precipitates are observed, and it should be used quickly after opening and stored within 24 hours. It is safest not to use products with damaged rubber stoppers. It is preferable not to use this medication in patients with a history of myocardial infarction.

Serious side effects

Urticaria, rash, anaphylactic shock, breathing difficulties, respiratory arrest, shock, bronchospasm, severe allergic reactions, asthma attacks, severe edema accompanied by increased blood pressure.

Mild side effects

• Nausea
• vomiting
• chest discomfort
• palpitations
• rapid heartbeat (tachycardia)
• increased blood pressure
• chills
• fever
• headache
• urinary tract spasms

This medication should be stored in a sealed container to avoid contact with air, at a temperature between 1 degree and 30 degrees Celsius. This way, the drug's efficacy can be well maintained and deterioration can be prevented.

Appearance

Injection containing a colorless to light yellow transparent liquid in a multilayer film plastic container, made of polypropylene, intended for aqueous injection.

Package unit

For domestic use - 250 milliliters/box