Medication info

Curesol Injection

Prescription medicationInjections
Ingredient · strength
L-Isoleucine›0.59g / 100mLL-Leucine›0.77g / 100mLL-Lysine Acetate›0.87g / 100mLL-Methionine›0.45g / 100mLL-Phenylalanine›0.48g / 100mLL-Threonine›0.34g / 100mLL-Tryptophan›0.13g / 100mLL-Valine›0.56g / 100mLL-Alanine›0.6g / 100mLL-Arginine›0.81g / 100mLL-Histidine›0.24g / 100mLL-Proline›0.95g / 100mLL-Serine›0.5g / 100mLGlycine›1.19g / 100mLL-Cysteine Hydrochloride Hydrate›0.02g / 100mL
Manufacturer / importer
(주)종근당
Appearance
A colorless to pale yellow transparent solution contained in a polypropylene aqueous injection container.
Packaging
For internal use - 250 milliliters/box
Approval status
Active

MFDS item code 199200564 · Notified 1992.06.09

Summary

Main use
Improvement of hypoproteinemia and malnutrition
Who uses it
Adults · Children
Adult dosage
Adults: Total amino acids of 1 to 1.5 g per kg of body weight per day, administered as a maximum dose by drip. Infusion rate: A concentration of approximately 10 g of total amino acids is preferable within 60 minutes, with a principle of administering 30-40 drops over 1 minute.
Children's dosage
For children, the dosage and infusion rate should be adjusted.

Ingredients

Manufacturer
(주)종근당

Efficacy & effects

Improvement of hypoproteinemia and malnutrition

  • Hypoproteinemia
  • malnutrition
View approved original text

Amino acids are used to supplement nutrients needed for hypoproteinemia, malnutrition, and before and after surgery.

Dosage and Administration

Adult dosage

Adults: Total amino acids of 1 to 1.5 g per kg of body weight per day, administered as a maximum dose by drip. Infusion rate: A concentration of approximately 10 g of total amino acids is preferable within 60 minutes, with a principle of administering 30-40 drops over 1 minute.

Children's dosage

For children, the dosage and infusion rate should be adjusted.

Precautions

This drug must be used under the guidance of a physician. It should not be used in patients with hepatic coma or those at risk for hepatic coma. Patients with severe renal impairment or high blood nitrogen levels should also avoid this medication. It should not be administered to patients with problems in nitrogen metabolism, severe heart failure, or pulmonary edema with fluid retention. This drug should be avoided in patients with very low or no urine output and those with abnormally high sodium or chloride levels. It should be used cautiously in patients with severe acidosis, congestive heart failure, or those with edema due to sodium retention. Patients with high potassium levels or difficulty excreting potassium, as well as those with liver or kidney function issues, need to exercise caution. This medication contains sodium bisulfite, which can cause allergic reactions or asthma attacks, so asthmatic patients should be particularly careful. While using this drug, symptoms such as rash, nausea, vomiting, chest discomfort, palpitations, and increased blood pressure may arise, so in case of any unusual symptoms, it should be stopped immediately and a doctor consulted. Large or rapid administration may lead to acidosis, and symptoms such as chills, fever, headaches, or difficulty breathing may occur. Patients with impaired liver or kidney function are at risk of elevated blood nitrogen levels, and severe liver dysfunction may lead to a comatose state. This drug includes electrolytes, so caution should be exercised regarding electrolyte balance during large doses. Diabetic patients should frequently monitor their blood glucose levels. Care is required due to potential interactions with other medications, especially when used with tetracycline antibiotics. Its safety has not been established for pregnant women, so it should only be administered when the benefits outweigh the risks. In children, doses should be adjusted to account for their potential immature liver function, with frequent checks of blood ammonia levels. Elderly patients may have diminished physical function, thus it is advisable to administer slowly and adjust the dosage accordingly. This drug should be administered slowly intravenously, as rapid injections may induce chills or vomiting and increase the loss of amino acids via the kidneys. Maintain strict aseptic conditions during use, and do not use if the solution has changed color or become opaque. During storage, keep the package intact until opened, and any remaining solution should be used within 24 hours after opening. Finally, it is safest for patients with a history of myocardial infarction or heart disease to refrain from using this drug.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rashes with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, severe skin reactions, respiratory distress, asthma attacks, coughing accompanied by fever and respiratory abnormalities, yellowing of the skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden...

Mild side effects

  • Nausea
  • vomiting
  • chest discomfort
  • palpitations
  • tachycardia
  • increased blood pressure
  • chills
  • fever
  • headache
  • urinary spasm
Show 17 more
  • metabolic acidosis
  • hypophosphatemia
  • alkalosis
  • hyperglycemia
  • diabetes
  • osmotic diuresis and dehydration
  • reactive hypoglycemia
  • elevated liver enzymes
  • vitamin deficiencies and excesses
  • electrolyte imbalances
  • childhood hyperammonemia
  • elevated BUN
  • serum amino acid imbalances
  • metabolic alkalosis
  • systemic nitrogenemia
  • hyperammonemia
  • and perception changes.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to protect it from exposure to air, preferably at room temperature between 1 to 30 degrees Celsius. Storing it this way helps maintain its effectiveness over time.

Appearance and packaging

Appearance

A colorless to pale yellow transparent solution contained in a polypropylene aqueous injection container.

Package unit

For internal use - 250 milliliters/box

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.