Medication info

Oflocacin Tablets (Ofloksacin)

Prescription medicationExpired
Ingredient · strength
Ofloxacin›Strength being verified
Manufacturer / importer
Kookje Pharm. Co., Ltd.
Appearance
White round coated tablet
Packaging
10, 100, 250, 500 tablets
Approval status
Expired

MFDS item code 199200412 · Notified 1992.09.18

This product's status changed to Expired on 2023.04.01. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of respiratory, ear, nose and throat, skin, and eye infections; genitourinary and intestinal infections; combination treatment for leprosy
Who uses it
Adults
Adult dosage
For adults, the usual dose is 300~600 mg of ofloxacin per day, divided into 2~3 doses. For leprosy, take 400~600 mg of this medicine per day, divided into 2~3 doses. In principle, it should be used in combination with other antileprosy medicines. Adjust the dose as appropriate according to age and symptoms.

Ingredients

Manufacturer
Kookje Pharm. Co., Ltd.

Efficacy & effects

Treatment of respiratory, ear, nose and throat, skin, and eye infections; genitourinary and intestinal infections; combination treatment for leprosy

  • Complex skin infections
  • soft tissue infections
  • acute otitis media
  • chronic suppurative otitis media
  • chronic cholesteatomatous otitis media
  • acute bacterial sinusitis
  • chronic bacterial sinusitis
  • community-acquired pneumonia
  • chronic bronchitis
  • acute exacerbation of chronic obstructive pulmonary disease
  • acute pyelonephritis
  • uncomplicated acute cystitis
View approved original text

This medication is a fluoroquinolone antibiotic that is effective against various bacteria such as staphylococcus, streptococcus, and E. coli. It is used for complex skin and soft tissue infections, acute and chronic otitis media, and bacterial sinusitis, and it is also effective for acute exacerbations of community-acquired pneumonia and chronic obstructive pulmonary disease. Additionally, it is applicable for urinary tract infections such as acute pyelonephritis, cystitis, and prostatic infections, as well as gastrointestinal infections such as bacterial dysentery and enteritis. It is also used for infections of the uterus and adnexae in women, as well as eye infections (blepharitis, sties, corneal ulcers, etc.) and in combination therapy for leprosy. However, this medication is recommended for use only when other treatments are not available due to the potential for serious adverse reactions. Overall, it is used extensively for a variety of bacterial infections, improving symptoms.

Dosage and Administration

Adult dosage

For adults, the usual dose is 300~600 mg of ofloxacin per day, divided into 2~3 doses. For leprosy, take 400~600 mg of this medicine per day, divided into 2~3 doses. In principle, it should be used in combination with other antileprosy medicines. Adjust the dose as appropriate according to age and symptoms.

Precautions

This medication is a fluoroquinolone antibiotic and can cause serious side effects such as tendon-related disorders including tendonitis or tendon rupture, peripheral neuropathy, and central nervous system adverse reactions. If these symptoms occur, you must immediately stop taking the drug and it should not be administered to patients with myasthenia gravis. Additionally, this medication is used only for certain infections such as acute bacterial rhinosinusitis, acute exacerbation of chronic bronchitis, uncomplicated urinary tract infections, and acute otitis media when no other treatment options are available. Elderly patients, those with decreased renal function, and patients taking corticosteroids are at higher risk for tendon rupture and should avoid concurrent use, and treatment should be stopped immediately if pain or inflammation occurs. This medication can worsen symptoms in patients with myasthenia gravis, and there is a potential for seizures or central nervous system symptoms, so caution is advised for patients with epilepsy or central nervous system disorders. It should not be used during pregnancy or in women who may become pregnant, nursing mothers, or growing children and adolescents. This medication may cause various side effects such as allergic reactions, liver and kidney dysfunction, gastrointestinal disorders, blood disorders, neuropsychiatric symptoms, skin diseases, musculoskeletal disorders, respiratory and circulatory system disorders, so you should promptly consult a healthcare professional if abnormal symptoms occur. Furthermore, this medication may interact with other drugs, so caution is needed when taken with anticoagulants, antidiabetic agents, antacids, or immunosuppressants. During administration, adequate hydration is required, and exposure to strong sunlight or UV light should be avoided, and care should be taken when driving or operating machinery for dizziness. In case of overdose, immediately visit a medical institution for appropriate treatment, as this medication may not be completely removed by hemodialysis. When storing, keep out of reach of children and do not transfer to another container.

Side effects

Tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects, exacerbation of myasthenia gravis, anaphylactic shock, anaphylactoid reactions, rash, itching, erythema, edema, fever, warmth, vesicles, erythema, phototoxic reactions, hematuria, acute renal failure, kidney stones, interstitial nephritis, increased BUN, elevated serum creatinine, jaundice, liver failure, elevated AST/ALT, increased ALP, elevated γ-GTP, increased total bilirubin, cholestatic jaundice, fulminant hepatitis, membranes colitis, colitis accompanied by bloody stools, abdominal pain, frequent diarrhea, nausea, vomiting, gastric and abdominal discomfort, diarrhea, cirrhosis, anorexia, stomach and abdominal pain, dyspepsia, chest pain, dryness of the mouth, taste disturbance, stomatitis, glossitis, abdominal bloating, constipation, dysphagia, gastrointestinal bleeding, oral mucosal pain, intestinal perforation, anemia, leukopenia, decreased hemoglobin, decreased hematocrit, thrombocytopenia, eosinophilia, agranulocytosis, thrombotic thrombocytopenic purpura, petechial and ecchymotic hemorrhage, prolonged prothrombin time, reversible bone marrow suppression, lymphocytopenia, neutropenia, increased ESR, insomnia, dizziness, headache, seizures, tremors, numbness, peripheral nerve disorders, visual disturbances, auditory disturbances, hallucinations, drowsiness, nervous irritability, sleep disorders, confusion, anxiety, depression, restlessness, hyperactivity, delirium, suicidal thoughts, suicide, perceptual disturbances, olfactory and vestibular sensory disturbances, ataxia, aphasia, heaviness of the head, skin and mucous membrane syndrome, toxic epidermal necrolysis, arthralgia, myalgia, muscle weakness, myositis, fatigue, elevated CPK, increased myoglobin, rhabdomyolysis, pharyngitis, dyspnea, bronchospasm, allergic pneumonia, epistaxis, stridor, fever, cough, abnormal chest X-ray, eosinophilia, interstitial pneumonia, cerebral thrombosis, pulmonary edema, tachycardia, hypertension, hypotension, palpitations, vasodilation, circulatory collapse, QT prolongation, ventricular tachycardia, dysuria, frequent urination, urinary retention, anuria, polyuria, pyuria, diabetes, proteinuria, alkaline urine, vaginitis, vaginal candidiasis, increased vaginal discharge, pruritus of the female genitals, menstrual irregularities, uterine cramps, female genital rash, pain, irritation, burning sensation, hypoglycemic symptoms, limb pain, malaise, fever, drowsiness, nausea, flushing of the face, facial edema, numbness, inaccurate speech, loss of orientation

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent air or moisture from entering. This will help maintain the effectiveness of the drug for as long as possible.

Appearance and packaging

Appearance

White round coated tablet

Package unit

10, 100, 250, 500 tablets

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.