Medication info
Unimeton Tablet (Nabumetone)

Unimeton Tablet (Nabumetone)

Prescription medicationTabletOral
Ingredient · strength
Nabumetone›500mg / 1 tablet
Manufacturer / importer
Donggwang Pharmaceutical Co., Ltd.
Appearance
Yellow round film-coated tablets
Packaging
500 tablets/bottle, 30 tablets/bottle
Approval status
Active

MFDS item code 199200248 · Notified 1992.03.17 · Insurance code 645902450

Summary

Main use
Relief of inflammation and pain associated with arthritis (osteoarthritis, etc.)
Who takes it
Adults · Children
Adult dose
This medication is for oral use. Swallow without chewing (tablets only). Adults: Administer 1 g of nabumetone orally once daily at bedtime. If symptoms are severe, persistent, or rapidly worsening, administer an additional 500 mg∼1 g of this medication orally in the morning. Older adults: As with many other medications, older patients may have higher plasma concentrations. Do not exceed a maximum of 1 g per day; in some cases, 500 mg may provide satisfactory symptom relief.
Child dose
Children: Clinical data on the use of this preparation in children are not yet available.

Ingredients

Manufacturer
Donggwang Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of inflammation and pain associated with arthritis (osteoarthritis, etc.)

  • Osteoarthritis
  • degenerative arthritis
  • rheumatoid arthritis
View approved original text

Osteoarthritis and rheumatoid arthritis are conditions accompanied by inflammation and pain in the joints. This medication helps reduce the inflammation and relieve the pain, allowing patients to perform daily activities more comfortably. It slows down cartilage damage in osteoarthritis and regulates inflammation caused by immune response in rheumatoid arthritis. Additionally, it is effective in restoring joint function and reducing pain. This drug is used for both conditions through its anti-inflammatory and analgesic actions.

How to take

Adult dose

This medication is for oral use. Swallow without chewing (tablets only). Adults: Administer 1 g of nabumetone orally once daily at bedtime. If symptoms are severe, persistent, or rapidly worsening, administer an additional 500 mg∼1 g of this medication orally in the morning. Older adults: As with many other medications, older patients may have higher plasma concentrations. Do not exceed a maximum of 1 g per day; in some cases, 500 mg may provide satisfactory symptom relief.

Child dose

Children: Clinical data on the use of this preparation in children are not yet available.

Precautions

This drug may pose a risk of gastric bleeding in individuals who consume three or more alcoholic beverages daily, so it is essential to consult a doctor or pharmacist. This medication may increase the risk of cardiovascular diseases, therefore patients with a history of heart disease or stroke, or other risk factors should be particularly cautious. During the use of this drug, cardiovascular symptoms may appear, so patients and doctors should carefully monitor these symptoms. This medication can cause serious gastrointestinal adverse reactions, such as bleeding, ulcers, or perforations, so elderly patients or those with a history of gastrointestinal diseases should be particularly careful. Care should be taken to avoid co-administration with other medications that increase the risk of gastrointestinal bleeding or ulcers, and treatment should be discontinued immediately if abnormal symptoms occur. Patients with peptic ulcers, severe blood disorders, liver dysfunction, kidney dysfunction, or heart disorders, or those with hypersensitivity to this drug should not take it. Patients with a history of aspirin asthma or allergic reactions to aspirin and other non-steroidal anti-inflammatory drugs should not use this medication. This drug is not to be administered to pregnant women or women who may become pregnant, nursing mothers, or children and adolescents under 15 years of age, as well as patients with inflammatory bowel diseases. Patients with blood disorders, liver dysfunction, kidney dysfunction, heart disorders, or a history of allergies should use this drug cautiously, and elderly patients should also exercise caution. This medication can rarely cause severe side effects such as shock, anaphylaxis, serious skin reactions, liver and kidney dysfunction, or respiratory problems, so patients should consult a doctor immediately if any abnormal symptoms appear. Long-term use of this drug requires regular blood tests and monitoring of liver and kidney function, and patients should avoid driving or operating hazardous machinery if they experience dizziness or drowsiness during treatment. When used alongside other non-steroidal anti-inflammatory drugs or specific medications, the risk of side effects may increase, so it is crucial to inform the doctor of any other medications being taken. It should not be taken during pregnancy as it may harm the fetus, nor during breastfeeding as it can be transmitted through breast milk and affect the infant. In case of overdose, symptoms such as headache, nausea, vomiting, gastrointestinal bleeding, or coma may occur, and immediate medical attention should be sought. This drug should be kept out of reach of children and care should be taken not to transfer it to other containers.

Side effects

  • Shock
  • anaphylaxis-like symptoms
  • respiratory distress
  • urticaria
  • hypotension
  • angioedema
  • facial swelling
  • rash
  • itching
  • dyspepsia
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  • abdominal pain
  • epigastric discomfort
  • upper abdominal pain
  • abdominal bloating
  • loss of appetite
  • nausea
  • vomiting
  • hematemesis
  • diarrhea
  • constipation
  • pneumoperitoneum
  • gastritis
  • peptic ulcer
  • perforation
  • gastrointestinal bleeding
  • gastrointestinal disorders
  • hematochezia
  • melena
  • ulcerative colitis
  • onset or exacerbation of Crohn's disease
  • pancreatitis
  • stomatitis
  • dry mouth
  • dizziness
  • headache
  • confusion
  • fear
  • nervous irritability
  • tension
  • insomnia
  • drowsiness
  • sensory disturbances
  • elevated AST
  • elevated ALT
  • elevated AL-P
  • liver failure
  • hepatitis
  • jaundice
  • nephrotic syndrome
  • renal failure
  • urinary disorders
  • interstitial nephritis
  • acute tubular necrosis
  • papillary necrosis
  • elevated urine protein
  • elevated BUN
  • elevated serum creatinine
  • interstitial pneumonia
  • respiratory distress
  • bronchospasm
  • asthma
  • epistaxis
  • vascular edema
  • pseudoporphyria
  • hair loss
  • erythema multiforme
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
  • sweating
  • photosensitivity reactions
  • thrombocytopenia
  • neutropenia
  • agranulocytosis
  • leukopenia
  • leukemia
  • aplastic anemia
  • hemolytic anemia
  • vasculitis
  • hypertension
  • heart failure
  • myopathy
  • neck stiffness
  • uterine bleeding
  • menorrhagia
  • tinnitus
  • ear disorders
  • abnormal vision
  • visual impairment
  • optic neuritis
  • edema
  • fatigue
  • weakness
  • aseptic meningitis
  • headache
  • nausea
  • vomiting
  • epigastric pain
  • gastrointestinal bleeding
  • diarrhea
  • disorientation
  • excitement
  • coma
  • dizziness
  • tinnitus
  • fainting
  • seizures
  • acute renal failure
  • liver damage

Not everyone experiences these, and they can vary from person to person.

Storage

This drug should be stored in a tightly sealed container to prevent air from entering, and it is safe to store at room temperature between 1 to 30 degrees Celsius. This will help maintain the drug's effectiveness and prevent it from deteriorating.

Appearance and packaging

Appearance

Yellow round film-coated tablets

Package unit

500 tablets/bottle, 30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.