Carbamazepine CR Tablet

Adult dose

1. Epilepsy Start treatment at a low dose and increase it slowly until the optimal effect is achieved. The dose of this drug should be adjusted to adequately control seizures in each individual patient. Determination of blood levels may help achieve the optimal dose. The therapeutic blood concentration of carbamazepine for epilepsy is known to be 4-12 μg/mL (17-50 micromoles/L). 1) Adults: The initial dose of carbamazepine is 200-400㎎ per day orally in 1-2 divided doses, and should be increased slowly until the optimal effect is achieved (600㎎ per day). The dose may be increased to 1200㎎ per day according to symptoms. 2. Trigeminal neuralgia Adults: The initial dose of this drug is 200-400㎎ per day, and may be administered in divided doses up to 600 mg per day. The dose may be increased to 800mg per day according to symptoms. 3. Mania, manic states of manic-depressive illness, and agitation in schizophrenia Adults: The initial dose of this drug is 200-400㎎ per day in 1-2 divided doses, and should be increased slowly until the optimal effect is achieved (600㎎ per day). The dose may be increased to 1200㎎ per day according to symptoms. Adjust the dose as appropriate according to age and symptoms.

Child dose

1) Children: Administer 100-600㎎ per day in divided doses according to age and symptoms.

This medication may increase the risk of suicidal thoughts or behaviors, so mood changes or symptoms of depression must be closely monitored during treatment. This drug can cause severe skin reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis, so if you experience a rash or blistering, consult a doctor immediately. Some individuals, particularly those of Asian descent, may have a genetically higher risk of severe skin reactions to this drug, and genetic testing is recommended before administration. Taking this medication during pregnancy can cause malformations or growth disorders in the fetus, so pregnant women or women of childbearing age should consult a doctor before use and must utilize effective contraception. Patients with hypersensitivity to this drug, certain blood disorders, heart diseases, liver diseases, or a history of porphyria should avoid use. Common central nervous system side effects such as dizziness, drowsiness, and movement disorders may occur, so caution is advised when driving or operating dangerous machinery. Regular blood tests and liver function tests are required, and if there is a decrease in blood cell count or worsening of liver function, notify healthcare professionals immediately. This drug has many interactions with other medications, so if you are taking other drugs, you must inform your doctor or pharmacist, and particularly hormonal contraceptives may be less effective; it is advisable to use non-hormonal contraceptive methods in conjunction. In case of overdose, central nervous system depression, respiratory distress, and heart abnormalities can occur, so adhere to the prescribed dosage and seek immediate emergency treatment if any abnormal symptoms arise. This drug should be kept out of the reach of children and stored in its original container to prevent misuse or degradation of quality.

Suicidal thoughts, suicidal behavior, depression, abnormal changes in mood and behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, dizziness, headache, ataxia, drowsiness, fatigue, diplopia, nausea, vomiting, allergic skin reaction, leukopenia, thrombocytopenia, eosinophilia, leukocytosis, lymphadenopathy, agranulocytosis, aplastic anemia, hypoplasia of erythroid cells, anemia, megaloblastic anemia, reticulocytosis, hemolytic anemia, fever, rash, vasculitis, lymphedema, arthralgia, hepatic splenomegaly, abnormal liver function tests, cholestatic syndrome, angioedema, hypogammaglobulinemia, anaphylactic reaction, edema, fluid retention, weight gain, hyponatremia, somnolence, confusional state, hyperprolactinemia, gynecomastia, folate deficiency, decreased appetite, acute intermittent porphyria, mixed porphyria, cutaneous porphyria, hyperammonemia, visual hallucinations, auditory hallucinations, aggressive behavior, anxiety, restlessness, psychotic activation, tremor, fixed posturing, dystonia, facial spasm, nystagmus, oral-facial movement disorder, ocular motility disorder, speech disturbance, chorea, peripheral neuropathy, sensory disturbance, incomplete paralysis, taste disturbance, neuroleptic malignant syndrome, hepatic muscle spasms, aseptic meningitis, lens opacity, conjunctivitis, increased intraocular pressure, hearing impairment, hyperacusis, hearing loss, auditory distortion, electrocardiographic abnormalities, bradycardia, arrhythmia, syncope, worsening of coronary artery disease, congestive heart failure, nephropathy, lymphadenopathy, myocardial infarction, hypertension, hypotension, circulatory collapse, embolism, thrombophlebitis, PIE syndrome, pulmonary hypersensitivity, polydipsia, constipation, diarrhea, abdominal pain, pancreatitis, glossitis, stomatitis, cholestatic hepatitis, hepatocellular hepatitis, mixed hepatitis, jaundice, severe hepatitis, granulomatous hepatitis, liver failure, urticaria, allergic dermatitis, exfoliative dermatitis, erythroderma, systemic lupus erythematosus symptoms, pruritus, Stevens-Johnson syndrome, toxic epidermal necrolysis, photosensitivity, erythema multiforme, erythema nodosum, abnormal skin pigmentation, petechiae, acne, hyperhidrosis, alopecia, hirsutism, muscle weakness, osteomalacia, osteoporosis, arthralgia, myalgia, muscle cramps, tubular interstitial nephritis, renal failure, renal function impairment, urinary retention, frequent urination, sexual dysfunction, erectile dysfunction, sperm morphology abnormalities, fatigue, elevated γ-GTP, elevated alkaline phosphatase, elevated transaminases, elevated intraocular pressure, elevated cholesterol, increased high-density lipoprotein, increased triglycerides, abnormal thyroid function tests, increased prolactin, reactivation of herpes virus 6 infection, bone marrow failure, sedation, memory impairment, colitis, drug rash, acute generalized exanthematous pustulosis, lichen planus, nail loss, fracture, decreased bone density, falls, vesicular rash, pustular rash, mucosal rash, sleep disorder, oral edema

This medicine may be sensitive to air and moisture, so it must be stored in a tightly closed container. Also, it is advisable to store it in a dry place, avoiding areas with high humidity.

Appearance

This medicine is a beige-orange, divisible capsule-shaped tablet.

Package unit

30 tablets/bottle, 500 tablets/bottle