Medication info

Complex Sepen Suppository

OTC medicationSuppository직장
Ingredient · strength
Acetaminophen›125mgDL-Methionine›12.5mg
Manufacturer / importer
한미약품(주)
Appearance
It is a white to light yellow bullet-shaped suppository.
Packaging
10 pieces/box [5 pieces/foil x 2]
Approval status
Active

MFDS item code 199102142 · Notified 1991.10.21

Summary

Main use
Relief of cold (fever, pain)
Who it is inserted in
Adults · Children
Adult use
Insert the following dose deeply into the rectum 2 to 3 times a day. Insert the suppository into the rectum starting from the rounded end. If it is expelled due to rectal muscle tension, squeeze both thighs together for about 1 minute.
Child use
Ages 3 to 6 years: 2 pieces per dose Ages 1 to 2 years: 1 to 2 pieces per dose Ages 3 months to 12 months: 1 piece per dose Insert the suppository into the rectum starting from the rounded end. If it is expelled due to rectal muscle tension, squeeze both thighs together to keep it in.

Ingredients

Manufacturer
한미약품(주)

Efficacy & effects

Relief of cold (fever, pain)

  • Fever and pain due to colds
View approved original text

Used to relieve fever and pain caused by colds.

How to insert

Adult use

Insert the following dose deeply into the rectum 2 to 3 times a day. Insert the suppository into the rectum starting from the rounded end. If it is expelled due to rectal muscle tension, squeeze both thighs together for about 1 minute.

Child use

Ages 3 to 6 years: 2 pieces per dose Ages 1 to 2 years: 1 to 2 pieces per dose Ages 3 months to 12 months: 1 piece per dose Insert the suppository into the rectum starting from the rounded end. If it is expelled due to rectal muscle tension, squeeze both thighs together to keep it in.

Precautions

This medication may cause liver damage, so those who drink three or more glasses of alcohol regularly should consult a doctor or pharmacist before use. Persons who have had allergic reactions to this medication or its components, those with a history of asthma attacks, patients with peptic ulcers, and individuals with severe blood disorders or liver, kidney, or heart dysfunction should not use this medication. Additionally, individuals taking barbiturates or tricyclic antidepressants, and those who have consumed alcohol should avoid using this medication for safety reasons. Do not take this medication with other products containing acetaminophen to prevent liver damage. Avoid combining it with other antipyretic analgesics, cold medicines, and sedatives. Those with allergies or who have experienced allergic symptoms from medications, children, elderly individuals, pregnant or breastfeeding women, and people with liver or kidney diseases must consult a healthcare professional before use. If symptoms such as hives, swelling, difficulty breathing, chest tightness, skin rashes, vomiting, or jaundice occur after use, discontinue use immediately and consult a healthcare provider. This medication is for symptom relief, requiring regular check-ups with long-term use, and long-term use of the same medication should be avoided. Especially children with high fevers and elderly individuals should be carefully monitored after administration. Overdose can cause severe damage to the liver and kidneys, so immediate treatment should be sought even without symptoms. Store this medication out of reach of children, avoiding direct sunlight and moisture, in a cool place. Also, keep it in its original container and avoid transferring it to other containers.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema) (in the larynx, eyelids, lips, etc.), chest tightness, difficulty breathing, cold sweats, pallor, severe rashes with high fever, blistering, peeling skin, pain in oral/ocular mucosa, asthma attacks, jaundice (yellowing of skin or eyes), profound lethargy, sudden and severe headache, seizures, confusion, visual disturbances, paralysis, significantly reduced urine output, severe general swelling, and blood.

Mild side effects

  • Rash
  • erythema (redness)
  • itching
  • nausea
  • vomiting
  • loss of appetite
  • diarrhea
  • changes in stool
  • sweating
  • hypotension
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  • cyanosis
  • platelet dysfunction
  • thrombocytopenia
  • agranulocytosis
  • hemolytic anemia
  • methemoglobinemia
  • fixed drug eruptions.

Not everyone experiences these, and they can vary from person to person.

Interactions

Drug interactions

Do not use this medication with other products containing acetaminophen, other anti-inflammatory analgesics, or other antipyretic analgesics. Also, consult a doctor or pharmacist before using it in combination with barbiturates, tricyclic antidepressants, lithium, thiazide diuretics, or levodopa.

Food interactions

Caution is required when using this medication with alcohol.

Storage

This medication should be stored in a sealed container to prevent exposure to air or moisture. The appropriate storage temperature is between 1 degree and 30 degrees Celsius, avoiding excessively hot or cold environments.

Appearance and packaging

Appearance

It is a white to light yellow bullet-shaped suppository.

Package unit

10 pieces/box [5 pieces/foil x 2]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.