Orosin Tablet 100 mg (Ofloxacin)

Adult dose

○ The usual adult dose of ofloxacin is 300～600 mg per day in 2～3 divided doses. ○ For Hansen's disease, take 400～600 mg of this drug per day in 2～3 divided doses. In principle, use in combination with other anti-Hansen's disease drugs. Adjust the dose appropriately according to age and symptoms.

This medication is a fluoroquinolone antibiotic and can cause tendon-related disorders such as tendonitis or tendon rupture. If such symptoms occur, its use should be stopped immediately, and it should not be used in patients with myasthenia gravis due to the risk of exacerbating symptoms. Additionally, this medication can affect the nervous system and cause peripheral neuropathy or central nervous system disturbance symptoms. If such symptoms occur, medical consultation should be sought immediately. Patients with a history of epilepsy or seizures should use it with caution due to an increased risk of seizures. This medication should be administered cautiously to the elderly, patients with reduced kidney function, and those with certain genetic disorders, and its use is not recommended for pregnant or breastfeeding women and adolescents under 18. During use, photosensitivity reactions may occur, so exposure to strong sunlight or artificial ultraviolet light should be avoided, and use should be discontinued immediately if skin rash or itching occurs. This medication may interact with other drugs, especially anticoagulants, hypoglycemic agents, corticosteroids, and some antacids, so consultation with a physician or pharmacist is necessary before use. Additionally, adequate hydration is required during administration, and dizziness or drowsiness may occur, requiring caution when driving or operating machinery. Long-term use of this medication necessitates regular liver, kidney function, and blood tests, and any abnormal symptoms should be reported to healthcare personnel immediately. Finally, serious side effects can occur in case of overdose, so strict compliance with the indicated dosage and administration is essential, and it should be stored out of reach of children.

Tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects, exacerbation of myasthenia gravis, anaphylactic shock, anaphylactic reactions, rash, itching, redness, swelling, fever, warmth, photosensitivity reactions, hematuria, acute kidney failure, kidney stones, interstitial nephritis, increased BUN, increased serum creatinine, jaundice, liver failure, elevated AST, elevated ALT, elevated ALP, elevated γ-GTP, increased total bilirubin, cholestasis jaundice, fulminant hepatitis, membranous colitis, bloody stools, abdominal pain, diarrhea, nausea, vomiting, gastric and abdominal discomfort, cirrhosis, loss of appetite, abdominal pain, dyspepsia, chest pain, thirst, taste disturbances, stomatitis, glossitis, abdominal bloating, constipation, dysphagia, gastrointestinal bleeding, oral mucosal pain, intestinal perforation, anemia, leukopenia, decrease in hemoglobin, decrease in hematocrit, thrombocytopenia, eosinophilia, agranulocytosis, thrombocytopenic purpura, petechial and ecchymotic hemorrhages, prolonged prothrombin time, reversible bone marrow suppression, lymphopenia, neutropenia, increased ESR, insomnia, dizziness, headache, seizures, tremors, numbness, peripheral nerve disorders, visual disturbances, auditory disturbances, hallucinations, drowsiness, nervousness, sleep disturbances, confusion, anxiety, depression, restlessness, hyperactivity, delirium, seizures, nightmares, paranoia, disorientation, attention deficits, memory impairments, delirium, suicidal thoughts, suicide, perceptual disturbances, olfactory and vestibular sensory disorders, ataxia, aphasia, heaviness in the head, skin and mucous membrane syndrome, toxic epidermal necrolysis, arthralgia, myalgia, muscle weakness, myositis, lethargy, elevated CPK, increased myoglobin, rhabdomyolysis, pharyngitis, dyspnea, bronchospasm, allergic pneumonia, epistaxis, stridor, fever, cough, abnormal chest X-ray, eosinophilia, interstitial pneumonia, cerebral thrombosis, pulmonary edema, tachycardia, hypertension, hypotension, palpitations, vasodilation, circulatory collapse, QT prolongation, ventricular tachycardia, dysuria, frequent urination, urinary retention, anuria, polyuria, hematuria, storage urine, pyuria, diabetes, proteinuria, alkaline urine, vaginitis, vaginal candidiasis, increased vaginal discharge, female external genitalia itching, menstrual irregularities, uterine cramps, female genital rash, pain, irritation, burning sensation, hypoglycemic symptoms, limb pain, malaise, fever, aortic aneurysm, aortic dissection, cardiac valve regurgitation, cardiac valve insufficiency

This medication should be stored in a sealed container to prevent air ingress, and it is safe to store it at room temperature between 1°C and 30°C. Proper storage will help maintain the efficacy of the medication and prevent degradation.

Appearance

White or pale yellow round film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle