Innoen 0.9% Sodium Chloride Injection

Adult administration

As sodium chloride, typically administered as subcutaneous, intravenous, or rectal injections of 20~1,000mL. The dosage and rate of administration should be appropriately adjusted based on age, body weight, and symptoms.

This medication should be cut with great care to avoid glass fragments contaminating the ampoule during preparation. Extra caution is especially necessary when used in children or elderly patients. This medication should not be administered to patients with hypernatremia, excessive body fluid states, and edema or ascites due to liver cirrhosis. Caution should be exercised when administering to patients with heart or circulatory system dysfunction, reduced kidney function, low protein levels in the blood, abnormal sodium or potassium levels, high chloride levels in the body, peripheral or pulmonary edema, patients with pre-eclampsia during pregnancy, those undergoing certain hormone therapies, and also in children or the elderly. Rapid or excessive administration can lead to complications such as heart failure, edema, acidosis, and electrolyte imbalances in the blood. Additionally, side effects such as infection, pain, phlebitis, thrombosis at the injection site, infiltration outside the vessel, and excessive blood volume increase may occur. In case of side effects, administration should be stopped immediately, the patient's condition evaluated, and appropriate treatment provided. Remaining solution can be stored for testing if necessary. Regular monitoring of liquid balance, electrolyte concentrations, and acid-base balance changes, as well as clinical evaluations, are important during continuous administration of this medication. Extra caution should be applied when administering to pregnant women, nursing mothers, women of childbearing age, newborns, infants, children, and elderly patients. The container for this medication is made from PVC containing a plasticizer known as DEHP, which has been reported to affect reproductive development in animal studies. However, the actual risk to human beings is considered very low, so there is no need to worry as the risks of not using the medication are greater. Elderly patients may have decreased physical function, so the infusion rate should be slow and the dosage adjusted accordingly. When preparing this medication, compatibility with diluents must be verified, and the solution should be checked for color change, precipitates, or crystallization before administration. Patient skin and injection devices should be disinfected to prevent infection, and in cold weather, the medication should be warmed to body temperature before use. After opening or adding other medications, it should be used immediately, and any remaining solution should be discarded. During administration, it should be infused slowly.

Serious side effects

Congestive heart failure, edema

Mild side effects

Fever, local pain or reaction at the injection site, venous irritation, thrombophlebitis, extravasation, excessive blood volume, acidosis, serum electrolyte abnormalities

This medication should be stored in a sealed container to prevent air or moisture ingress. It is best stored at room temperature, avoiding direct sunlight and areas that are too hot or cold.

Appearance

A colorless and transparent solution filled in a plastic container for intravenous use, packed in translucent high-density polyethylene.

Package unit

50, 60, 100, 110, 250, 500, 1000 milliliters