Question 1

What are the indications and effects of Obid Tablet (Ofloxacin)?

Accepted Answer

This medication is used to treat various types of bacterial infections. It is effective for complex skin and soft tissue infections, as well as for ear infections including acute otitis media and chronic forms of otitis media. It is also used for bacterial sinusitis, community-acquired pneumonia, and acute exacerbations of chronic obstructive pulmonary disease. In the urinary tract, it is used for acute pyelonephritis, cystitis, prostatitis, and urethritis, as well as for gastrointestinal infections like bacterial dysentery and gastroenteritis. Additionally, it is effective for various infections such as pelvic inflammatory disease in women, intrauterine infections, and eye diseases. However, this medication is a fluoroquinolone and can have serious side effects, thus it should be used only when other treatment options are not available.

Question 2

What are the dosage and administration instructions for Obid Tablet (Ofloxacin)?

Accepted Answer

○ The usual adult dose is 300～600 mg of ofloxacin per day, divided into 2～3 doses.

○ For leprosy, 400～600 mg of this medicine per day is taken in 2～3 divided doses. In principle, it should be used in combination with other antileprosy medicines.

The dose may be adjusted appropriately according to age and symptoms.

Question 3

What are the side effects of Obid Tablet (Ofloxacin)?

Accepted Answer

Tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects, exacerbation of myasthenia gravis, anaphylactic shock, anaphylactic reactions, hypotension, respiratory distress, sensation of chest tightness, sweating, rash, itching, erythema, edema, fever, feeling of warmth, blisters, erythema, photosensitivity reactions, hematuria, acute renal failure, kidney stones, interstitial nephritis, elevated BUN, elevated serum creatinine, jaundice, liver failure, elevated AST, elevated ALT, elevated ALP, elevated γ-GTP, elevated total bilirubin, cholestatic jaundice, fulminant hepatitis, membranous colitis, bloody stool, abdominal pain, frequent diarrhea, nausea, vomiting, discomfort in the upper abdomen, diarrhea, cirrhosis, loss of appetite, abdominal pain, dyspepsia, chest pain, thirst, taste disturbance, stomatitis, glossitis, abdominal bloating, constipation, dysphagia, gastrointestinal bleeding, oral mucosal pain, bowel perforation, anemia, leukopenia, decreased hemoglobin, reduced hematocrit, thrombocytopenia, eosinophilia, agranulocytosis, thrombocytopenic purpura, petechiae, ecchymosis, prolonged prothrombin time, reversible bone marrow suppression, lymphopenia, neutropenia, increased ESR, insomnia, dizziness, headache, seizures, tremors, numbness, peripheral neuropathy, visual disturbances, diplopia, neglect, nystagmus, auditory disturbances, tinnitus, hearing loss, hallucinations, drowsiness, neuroexcitation, sleep disturbances, confusion, anxiety, depression, restlessness, distress, delusions, seizures, nightmares, paranoia, disorientation, attention deficit, memory impairment, delirium, suicidal thoughts, suicide, perceptual disturbances, reversible olfactory dysfunction, reversible vestibular dysfunction, ataxia, aphasia, heaviness in the head, skin and mucous membrane syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, Riel syndrome, arthralgia, myalgia, muscle weakness, myositis, asthenia, elevated CPK, increased serum myoglobin, increased urinary myoglobin, pharyngitis, bronchospasm, allergic pneumonia, nosebleed, wheezing, fever, cough, abnormal chest X-ray, interstitial pneumonia, cerebral thrombosis, pulmonary edema, tachycardia, hypertension, hypotension, palpitation, vasodilation, circulatory collapse, QT prolongation, ventricular tachycardia, dysuria, frequent urination, urinary retention, anuria, polyuria, pyuria, diabetes, proteinuria, alkaline urine, vaginitis, vaginal candidiasis, increased vaginal discharge, vulvar itching, menstrual irregularities, uterine cramps, genital rash, genital pain, genital irritation, burning sensation in the genital area, symptoms of hypoglycemia, limb pain, lethargy, fever

Question 4

What precautions should be taken when using Obid Tablet (Ofloxacin)?

Accepted Answer

This medication may cause tendon-related side effects such as tendonitis and tendon rupture, thus usage should be stopped immediately if unusual symptoms occur.

Peripheral neuropathy or central nervous system issues have also been reported, and treatment should be stopped if severe neurological adverse reactions occur.

Patients with myasthenia gravis may experience worsening symptoms if this medication is used, so it should not be administered.

When used with corticosteroids, the risk of tendon rupture is increased, thus concomitant use should be avoided. If pain or inflammation occurs, the medication should be stopped immediately and rest should be taken.

Due to the risk of seizures, caution is advised in patients with a history of epilepsy or central nervous system disorders.

This drug should not be administered to pregnant women, those who may become pregnant, nursing mothers, individuals under 18 years of age, and patients with a history of hypersensitivity.

Elderly patients and those with impaired kidney or liver function should have their doses and intervals adjusted and should be monitored carefully.

This medication may cause photoreactions, thus strong sunlight or exposure to artificial ultraviolet light should be avoided, and treatment should be discontinued if symptoms occur.

It may affect blood glucose control, so diabetic patients should carefully monitor their blood sugar levels.

There may be interactions with other medications, particularly with anticoagulants, nonsteroidal anti-inflammatory drugs, and antacids, so caution is advised when using these together.

Adequate hydration is necessary while taking this medication, and there may be neurological symptoms such as dizziness, so caution is advised when driving or operating machinery.

Adverse reactions reported include skin rashes, liver function abnormalities, kidney problems, digestive symptoms, blood abnormalities, and neuropsychiatric symptoms, so immediate consultation with medical personnel is required if symptoms occur.

When storing this medication, keep it out of reach of children and do not transfer it to another container for safety.

Obid Tablet (Ofloxacin)

Summary

Ingredients

Efficacy & effects

How to take

Adult dose

Precautions

Side effects

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