Medication info
Iyeon Nimodipine Tablet

Iyeon Nimodipine Tablet

Prescription medicationTabletOral
Ingredient · strength
Nimodipine›30mg / 1 tablet
Manufacturer / importer
Iyeon Pharmaceutical Co., Ltd.
Appearance
Round coated tablet, white to light yellow
Packaging
30 tablets/bottle, 500 tablets/bottle
Approval status
Active

MFDS item code 199100164 · Notified 1991.08.05 · Insurance code 658601120

Summary

Main use
Prevention and treatment of cerebrovascular spasm-related ischemic neurological disorders; improvement of symptoms of brain dysfunction
Who takes it
Adults
Adult dose
Swallow whole without chewing, with a small amount of liquid, regardless of meals. 1. Ischemic neurologic disorders due to cerebral vasospasm: After administering nimodipine injection for 5-14 days after hemorrhage, administer nimodipine 60 milligrams orally 6 times daily at 4-hour intervals for 7 days. 2. Cerebral dysfunction: Administer 30 milligrams of this medicine 3 times daily. Maintain an interval of at least 4 hours between doses. Do not use the oral and injectable formulations concomitantly. Adjust the dose as appropriate according to age and symptoms.

Ingredients

Manufacturer
Iyeon Pharmaceutical Co., Ltd.

Efficacy & effects

Prevention and treatment of cerebrovascular spasm-related ischemic neurological disorders; improvement of symptoms of brain dysfunction

  • Subarachnoid hemorrhage
  • cerebral vasospasm
  • ischemic neurological disorder
  • neurological dysfunction
  • lack of concentration
  • memory decline
  • depression
  • anxiety
View approved original text

This medication is used to prevent and treat ischemic neurological disorders caused by cerebral vasospasm following subarachnoid hemorrhage due to an aneurysm. It also has the effect of improving various neurological function disorders such as lack of concentration, memory impairment, depression, and anxiety due to cerebrovascular problems. Through these effects, it helps protect the patient's neurological function and enhance overall brain health.

How to take

Adult dose

Swallow whole without chewing, with a small amount of liquid, regardless of meals. 1. Ischemic neurologic disorders due to cerebral vasospasm: After administering nimodipine injection for 5-14 days after hemorrhage, administer nimodipine 60 milligrams orally 6 times daily at 4-hour intervals for 7 days. 2. Cerebral dysfunction: Administer 30 milligrams of this medicine 3 times daily. Maintain an interval of at least 4 hours between doses. Do not use the oral and injectable formulations concomitantly. Adjust the dose as appropriate according to age and symptoms.

Precautions

This medication should not be used in patients with hypersensitivity to this drug or its components. It is also safer not to administer it to pregnant women, women who may become pregnant, and nursing women. This medication should not be used in patients with severe liver dysfunction as its effects may become excessive. Furthermore, it should be avoided in patients taking certain antiepileptic medications such as Rifampicin, Phenobarbital, Phenytoin, and Carbamazepine, as the effectiveness of this medication may be reduced. This drug contains lactose, and it should not be administered to patients with lactose intolerance or related genetic disorders. Patients with cerebral edema or increased intracranial pressure, patients with impaired liver or kidney function, and patients with hypotension should use it with caution, and blood pressure and electrocardiogram conditions should be closely monitored to adjust the dosage if necessary. This medication is metabolized in the liver through a specific enzyme (CYP3A4), so caution is needed when taking medications that inhibit or promote the action of this enzyme, as they may change the blood concentration of this medication. For example, some antibiotics, antifungals, antidepressants, and antiepileptics fall into this category, so blood pressure changes should be monitored when taken together. Taking this medication may cause side effects such as nausea, gastrointestinal disturbances, headache, dizziness, drowsiness, hypotension, and swelling. In severe cases, thrombocytopenia or hypersensitivity reactions may occur, so if any abnormal symptoms arise, consult a doctor immediately. Dizziness may occur, so caution is needed when driving a car or operating dangerous machinery. Pregnant or nursing women should avoid taking this medication due to the lack of established safety, and if unavoidable, nursing should be discontinued. The safety and effectiveness in pediatric patients have not been sufficiently confirmed, so caution should be exercised in use. In the elderly, it should be used cautiously with regular check-ups if kidney function or cardiovascular function is significantly impaired. In case of overdose, symptoms such as hypotension, pulse abnormalities, gastrointestinal discomfort, or central nervous system symptoms may occur, so medication should be stopped immediately and emergency treatment sought. This medication should not be taken with grapefruit juice as it can increase blood concentration and the risk of side effects.

Side effects

  • nausea
  • gastrointestinal discomfort
  • bowel obstruction
  • constipation
  • diarrhea
  • abdominal distension
  • elevation of transaminases
  • elevation of alkaline phosphatase
  • elevation of gamma-GTP
  • headache
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  • dizziness
  • lightheadedness
  • hyperactivity
  • tremors
  • weakness
  • drowsiness
  • agitation
  • sweating
  • emotional depression
  • insomnia
  • increased anxiety
  • rebelliousness
  • hypotension
  • vasodilation
  • syncope
  • edema
  • blood pressure reduction
  • facial flushing
  • warmth sensation
  • skin erythema
  • peripheral edema
  • palpitations
  • bradycardia
  • tachycardia
  • chest pain
  • thrombocytopenia
  • acute hypersensitivity reaction
  • rash

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a container that is not permeable to light. Additionally, it is recommended to store it at room temperature, between 1 degree and 30 degrees Celsius. Storing it this way can help maintain the medication's effectiveness for a long time.

Appearance and packaging

Appearance

Round coated tablet, white to light yellow

Package unit

30 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.