Spitasin Tablets (Ciprofloxacin Hydrochloride)

Adult dosage

Typically, for adults, ciprofloxacin is taken as 250 to 500 mg orally twice daily between meals. In cases of severe complicated infections, the dosage can be increased to 750 mg twice daily. For acute infections, treatment usually lasts for 5 to 10 days, and it should be taken for at least 3 days after symptoms disappear. For patients with renal impairment, the dosage should be adjusted according to creatinine clearance. 1) > 50 mL/min : Regular

This medication may lead to serious side effects such as tendonitis and tendon rupture, peripheral neuropathy, and central nervous system effects; caution is required. It should particularly not be administered to patients with severe myasthenia gravis due to the risk of exacerbation of symptoms. This medication should be used restrictively for specific infections like acute bacterial rhinosinusitis, acute exacerbations of chronic bronchitis, uncomplicated urinary tract infections, and acute otitis media. Elderly patients, those with renal impairment, transplant recipients, and patients taking corticosteroids should avoid concurrent usage due to increased risk of tendon rupture. If tendon pain or inflammation occurs while taking this medication, use should be stopped immediately, and rest should be taken, avoiding any physical activity. Patients with a history of allergy to this drug or similar drugs, pregnant women or those who may become pregnant, nursing mothers, adolescents under 18 years of age, and patients with epilepsy should not take this medication. Special caution is needed when administering to patients with a history of seizures, severely impaired kidney function, elderly patients, and those with severe myasthenia gravis. While taking this medication, symptoms such as mental confusion, depression, hallucinations, seizures, visual or auditory disturbances, severe skin rashes, and liver function abnormalities may occur; if any abnormal symptoms appear, consult medical personnel immediately. This medication interacts with many other drugs, especially caution is needed when taken with theophylline, warfarin, sulfonylurea antidiabetic drugs, tizanidine, and ketoprofen. Additionally, this medication may cause photosensitivity reactions, so strong sunlight or artificial UV exposure should be avoided, and caution should be exercised when driving or operating machinery during treatment. Pregnant or nursing women should avoid taking this medication, and it should not be administered to children and growing adolescents. In case of overdose, renal function should be monitored, and emergency treatment should be performed as necessary, keeping the medication out of reach of children and avoiding exposure to direct sunlight and UV light.

Serious side effects

Tendonitis, tendon rupture, peripheral neuropathy, central nervous system effects, exacerbation of severe myasthenia gravis, anaphylactic reactions, anaphylactoid shock, serum sickness-like reactions, (life-threatening) bone marrow suppression, abnormal liver function tests, jaundice, liver dysfunction, hepatitis, cholestatic jaundice, hepatic necrosis, severe skin adverse reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis), acute generalized exanthematous pustulosis, seizures, status epilepticus, mental confusion,

Mild side effects

• Fungal superinfection
• thrombocytopenia
• leukopenia
• anemia
• hypoglycemia
• hyperglycemia
• decreased appetite
• nausea
• diarrhea
• vomiting

This medication should be stored in a tightly closed container to prevent air or moisture from entering. This helps maintain the medication's effectiveness over a longer period and prevents deterioration.

Appearance

White round film-coated tablets

Package unit

① (10 tablets/PTP)×1,3,10 ② 30 tablets (bottle), 100 tablets (bottle), 300 tablets (bottle)