Shinpoong Tranexamic Acid Injection 500 mg

Adult dosage

Capsule form: tranexamic acid, typically administered orally in divided doses of 750 to 2000 mg per day for adults, 3 to 4 times. Injection form: tranexamic acid, typically administered as an intravenous or intramuscular injection in split doses of 250 to 500 mg per day for adults. For bleeding during or after surgery, 500 to 1000 mg may be administered intravenously or 500 to 2500 mg via intravenous drip as needed.

This medication should be carefully opened as it is in a glass ampoule. If glass fragments get mixed in, side effects may occur; therefore, special care should be taken when used in children and the elderly. This medication should not be used in certain patients, for example, those taking other medications that affect blood clotting or with a history of thromboembolism. Additionally, individuals allergic to this medication or its components should not use it. Moreover, this medication should not be administered via spinal injection. Patients with thrombosis or at risk of thrombosis, those confined to bed for long periods after surgery, and patients with reduced kidney function should exercise caution when using this medication, as it may stabilize blood clots or increase clot formation. Furthermore, careful use under the supervision of an expert is necessary for patients with bleeding disorders or specific severe bleeding conditions. When using this medication, shock or allergic reactions may rarely occur, so if symptoms develop, administration should be stopped immediately and appropriate treatment should be sought. Temporary visual disturbances, digestive disorders, drowsiness, and headaches may occur, and thromboembolism may rarely develop. There have been reports of seizures in patients who received this medication during cardiovascular surgery, which necessitates caution. Incorrect administration via spinal injection may lead to serious side effects. When used in conjunction with other blood coagulation-related medications, there may be an increased risk of clot formation, therefore, it should be administered carefully according to the advice of a healthcare professional. Particularly when used with hormonal contraceptives, there may be an increased risk of thromboembolism, thus non-hormonal contraceptive methods are recommended. In pregnant women, as this medication crosses the placenta, it should be administered with caution, and during breastfeeding, while a small amount of the medication may be transmitted through breast milk, it is expected to have little impact on the baby. Elderly patients may have reduced bodily functions, so it is important to adjust the dosage of this medication accordingly. In cases of overdose, symptoms such as nausea, vomiting, and dizziness may appear, so if these symptoms occur, immediate consultation with healthcare personnel is necessary, and adequate fluid intake should be ensured to help expel the medication. This medication should be administered slowly via intravenous injection; rapid injection may cause nausea, chest discomfort, palpitations, low blood pressure, and dizziness. Finally, this medication may undergo chemical changes when mixed with certain other medications, so it should always be discussed with a healthcare professional before combined use.

Serious side effects

• Shock
• Thromboembolism
• Seizures
• Convulsions
• Ureteral obstruction

Mild side effects

• Rarely, allergic symptoms such as itching, rash, and flushing
• Temporary color vision disturbances
• Nausea, vomiting, diarrhea
• Drowsiness, headache
• In cases of overdose: nausea, vomiting, orthostatic hypotension
• In cases of rapid administration: nausea, chest discomfort, palpitations, low blood pressure, dizziness

This medication should be stored in a sealed container to prevent exposure to air or moisture, ideally at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's efficacy and prevent degradation.

Appearance

It is a colorless, transparent liquid or a colorless, transparent ampoule injection.

Package unit

For domestic use - 5 milliliters/ampoule [x 50], for export - 5 milliliters/ampoule [x 10]