Xyren Tablet 0.5 mg (Alprazolam)

Adult dose

Determine the dose individually to achieve maximum benefit. The usual daily doses listed below are suitable for most patients, but higher doses may be required. In such cases, increase the dose gradually to avoid adverse effects. The risk of dependence may increase with the dose and duration of treatment. Therefore, use the lowest effective dose for the shortest possible duration and frequently reassess the need to continue treatment. ○ Adults 1. The initial regimen is alprazolam 0.25-0.5㎎ per dose, 3 times daily, with a maximum dose of 4㎎ per day. For elderly patients and patients with hepatic impairment or debility, the initial regimen is 0.25㎎ per dose, 2-3 times daily. Reduce the dose if adverse effects occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ per day of this drug orally in 3 divided doses. If increasing the dose, increase gradually to a maximum of 2.4㎎ per day and administer orally in 3-4 divided doses. For elderly patients, the initial regimen is 0.4㎎ per dose, 1-2 times daily, with a maximum dose of 1.2㎎ per day. 3. Panic disorder Start with an initial dose of 0.5㎎ of this drug, then increase by no more than 1㎎ at intervals of 3-4 days according to the patient's response to treatment, to an average daily dose of 5-6㎎ administered in 3-4 divided doses. To discontinue treatment, reduce the dose by no more than 0.5㎎, usually at 3-day intervals; a lower dose reduction may be required in some cases.

This drug is a benzodiazepine that acts on the central nervous system and is used for the treatment of anxiety and panic disorders. Caution is required when taking this drug with narcotics, as it may lead to severe sedation, respiratory depression, coma, or even death. Moreover, this drug carries a risk of abuse and dependence; thus, it should be taken strictly according to the prescribed dosage by a physician, and sudden discontinuation must be avoided. It should not be used in cases of hypersensitivity to this drug, acute angle-closure glaucoma, severe myasthenia gravis, severe respiratory failure, or significantly impaired liver function. It should also be avoided in women in late pregnancy and in patients with certain genetic lactose intolerance. Patients with heart, liver, or kidney diseases, as well as the elderly and frail patients, may experience more severe side effects; therefore, it should be used with caution. Drowsiness or decreased concentration may occur while taking this medication, thus driving or operating hazardous machinery should be avoided. Regular blood tests and liver function tests are required during long-term treatment, and if any unusual symptoms occur, a doctor should be consulted immediately. This medication can potentiate the effects when taken with other central nervous system depressants or alcohol and should therefore be avoided or used very cautiously. Pregnant or breastfeeding women should consult a physician before taking this medication, and it is advisable to avoid administration while breastfeeding. Safety and efficacy in children and adolescents under 18 years have not been established. In cases of overdose, severe drowsiness, respiratory depression, and coma may occur, and emergency treatment should be sought immediately. Attention should be paid to drug interactions while taking this medication. This medication should be stored out of reach of children and kept in its original container to prevent degradation and misuse.

• Mild discomfort
• insomnia
• abdominal and muscle cramps
• vomiting
• sweating
• tremors
• convulsions
• seizures
• agitation
• increased muscle rigidity

This drug is sensitive to light and air; hence, it should be stored in a sealed container that blocks light. Additionally, it should be stored at room temperature, avoiding excessively hot or cold places.

Appearance

Orange oval tablet

Package unit

30 tablets/bottle, 100 tablets/bottle