Medication info
Alprazolam Tablet 0.5 mg (Alprazolam)

Alprazolam Tablet 0.5 mg (Alprazolam)

Prescription medicationTabletOral
Ingredient · strength
Alprazolam›0.5mg / 1 tablet
Manufacturer / importer
Hanin Pharmaceutical Co., Ltd.
Appearance
Light orange oval tablets
Packaging
30 tablets/bottle, 200 tablets/bottle, 200 tablets (10 tablets/PTP × 20)
Approval status
Active

MFDS item code 198702202 · Approved 1987.05.30 · Insurance code 657200490

Summary

Main use
Relief of symptoms of anxiety disorders, anxiety associated with depression, panic disorder, and psychosomatic disorders
Who takes it
Adults
Adult dose
To achieve the greatest benefit, determine the dose for each individual. The usual daily doses listed below are suitable for most patients, but higher doses may be required. In such cases, increase the dose gradually to avoid adverse effects. The risk of dependence may increase with the dose and duration of treatment. Therefore, administer the lowest effective dose for the shortest possible period and frequently reassess the need to continue treatment. ○ Adults 1. As the initial dose, administer 0.25-0.5㎎ of alprazolam per dose 3 times daily, with a maximum dose of 4㎎ per day. For elderly patients, patients with hepatic impairment, and debilitated patients, the initial dose is 0.25㎎ per dose 2-3 times daily. Reduce the dose if adverse effects occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ of this medicine per day orally in 3 divided doses. If increasing the dose, increase it gradually up to a maximum of 2.4㎎ per day and administer orally in 3-4 divided doses. For elderly patients, the initial dose is 0.4㎎ per dose 1-2 times daily, with a maximum dose of 1.2㎎ per day. 3. Panic disorder Start with an initial dose of 0.5㎎ of this medicine and, depending on the patient's response to treatment, increase the dose by no more than 1㎎ at intervals of 3-4 days, to an average total daily dose of 5-6㎎ administered in 3-4 divided doses. When discontinuing treatment, reduce the dose by no more than 0.5㎎, usually at 3-day intervals; a slower reduction may be necessary in some cases.

Ingredients

Manufacturer
Hanin Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of symptoms of anxiety disorders, anxiety associated with depression, panic disorder, and psychosomatic disorders

  • Anxiety disorders
  • anxiety symptoms
  • anxiety associated with depression
  • psychosomatic disorders
  • gastric ulcers
  • duodenal ulcers
  • irritable bowel syndrome
  • autonomic nervous system imbalance
  • anxiety
  • tension
  • depression
  • sleep disorders
View approved original text

This medication helps treat anxiety disorders and alleviate anxiety symptoms; it is also effective for anxiety symptoms associated with depression. Additionally, it is used to improve anxiety, tension, depression, and sleep disorders resulting from psychosomatic disorders such as gastric or duodenal ulcers, irritable bowel syndrome, and autonomic nervous system imbalance. It also assists in the treatment of panic disorders. This medication significantly contributes to improving the quality of life for patients by relieving various anxiety-related symptoms.

How to take

Adult dose

To achieve the greatest benefit, determine the dose for each individual. The usual daily doses listed below are suitable for most patients, but higher doses may be required. In such cases, increase the dose gradually to avoid adverse effects. The risk of dependence may increase with the dose and duration of treatment. Therefore, administer the lowest effective dose for the shortest possible period and frequently reassess the need to continue treatment. ○ Adults 1. As the initial dose, administer 0.25-0.5㎎ of alprazolam per dose 3 times daily, with a maximum dose of 4㎎ per day. For elderly patients, patients with hepatic impairment, and debilitated patients, the initial dose is 0.25㎎ per dose 2-3 times daily. Reduce the dose if adverse effects occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ of this medicine per day orally in 3 divided doses. If increasing the dose, increase it gradually up to a maximum of 2.4㎎ per day and administer orally in 3-4 divided doses. For elderly patients, the initial dose is 0.4㎎ per dose 1-2 times daily, with a maximum dose of 1.2㎎ per day. 3. Panic disorder Start with an initial dose of 0.5㎎ of this medicine and, depending on the patient's response to treatment, increase the dose by no more than 1㎎ at intervals of 3-4 days, to an average total daily dose of 5-6㎎ administered in 3-4 divided doses. When discontinuing treatment, reduce the dose by no more than 0.5㎎, usually at 3-day intervals; a slower reduction may be necessary in some cases.

Precautions

This medication is a benzodiazepine that acts on the central nervous system to relieve anxiety and facilitate sedation. Taking this medication with narcotics can inhibit breathing, potentially leading to coma or death, so it should only be used with the minimum effective dose and duration when absolutely necessary. This medication carries a risk of misuse, so the patient's condition should be regularly monitored according to the physician's instructions during treatment, and any remaining medication must be stored and disposed of safely to prevent misuse. Patients with allergic reactions or certain conditions, such as acute angle-closure glaucoma, severe myasthenia gravis, severe respiratory failure, or severe liver dysfunction, should not take this medication. Patients with heart, liver, or kidney issues, elderly patients, or frail patients should use this medication cautiously, and extra caution is needed for those with a history of allergies. This medication can cause withdrawal symptoms, so do not discontinue abruptly but gradually reduce the dosage under the guidance of a physician. Drowsiness and decreased concentration may occur during treatment; therefore, avoid driving or operating dangerous machinery. Also, this medication can have enhanced sedative effects when taken with other central nervous system depressants or alcohol, so care should be taken not to take them together. During pregnancy, especially in the last three months, it should be avoided as it may affect the fetus, and breastfeeding should also be avoided or breastfeeding should be suspended if possible. Safety for children and adolescents under 18 years has not been established, so usage is not recommended. In case of overdose, severe drowsiness, movement disorders, coma, and respiratory depression may occur, and immediate medical treatment should be sought. Keep this medication out of reach of children, ensuring it is stored in its original packaging to prevent quality deterioration.

Side effects

  • Mild discomfort
  • insomnia
  • abdominal and muscle cramps
  • vomiting
  • sweating
  • trembling
  • convulsions
  • seizures
  • agitation
  • increased muscle rigidity
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  • sleep disorders
  • hallucinations
  • restlessness
  • anger
  • irritability
  • aggressive behavior
  • hostile behavior
  • hypersensitivity
  • hostility
  • obsessive thoughts
  • drowsiness
  • headache
  • depression
  • confusion
  • disorientation
  • decreased libido
  • anxiety
  • nervousness
  • increased libido
  • mania
  • rage
  • restlessness
  • drug dependence
  • hypomania
  • aggression
  • abnormal thinking
  • dyskinesia
  • substance abuse
  • ataxia
  • memory impairment
  • speech disorders
  • dizziness
  • balance disorders
  • cooperation difficulties
  • attention disorders
  • hypersomnia
  • somnolence
  • tremors
  • amnesia
  • autonomic nervous system imbalance
  • muscle tone abnormalities
  • blurred vision
  • constipation
  • dry mouth
  • nausea
  • gastrointestinal abnormalities
  • hepatitis
  • abnormal liver function
  • jaundice
  • dermatitis
  • angioedema
  • photosensitivity
  • muscle weakness
  • incontinence
  • urinary retention
  • sexual dysfunction
  • menstrual irregularities
  • fatigue
  • drug withdrawal syndrome
  • peripheral edema
  • weight loss
  • weight gain
  • increased intraocular pressure
  • delirium
  • insomnia
  • nervousness
  • syncope
  • dizziness
  • inability to sit still
  • thirst
  • diarrhea
  • increased salivation
  • tachycardia
  • palpitations
  • hypotension
  • hypertrophy
  • tremors
  • dermatitis
  • allergy
  • nasal congestion
  • weight gain
  • weight loss
  • fatigue
  • motor coordination disorders
  • memory impairment
  • involuntary movement disorders
  • decreased libido
  • confused state
  • muscle single contraction
  • changes in libido
  • weakness
  • abnormal muscle tone
  • syncope
  • inability to sit still
  • restlessness
  • disinhibition
  • sensory disturbances
  • polyuria
  • vascular motor disorders
  • unreality
  • abnormal dreams
  • fear
  • warm sensations
  • decreased salivation
  • abdominal discomfort
  • chest pain
  • hyperventilation
  • upper respiratory tract infection
  • tinnitus
  • muscle cramps
  • muscle rigidity
  • sweating
  • rash
  • increased appetite
  • decreased appetite
  • urination disorders
  • menstrual disorders
  • erectile dysfunction
  • edema
  • incontinence
  • infection
  • seizures
  • depersonalization
  • taste changes
  • double vision
  • increased bilirubin
  • elevated liver enzymes
  • jaundice
  • delirium
  • apathy
  • hyperactivity
  • dyspepsia
  • asthenia
  • chest pain
  • fatigue
  • falls
  • ataxia
  • concentration difficulties
  • excessive sleep
  • somnolence
  • muscle weakness
  • elevated liver enzymes
  • Stevens-Johnson syndrome
  • gynecomastia
  • galactorrhea
  • relaxation syndrome
  • nervousness
  • hypertonicity
  • breastfeeding difficulties
  • increased jaundice

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication in a tightly closed container that does not allow light in, ideally at room temperature. Proper storage helps maintain the medication's effectiveness and prevents degradation.

Appearance and packaging

Appearance

Light orange oval tablets

Package unit

30 tablets/bottle, 200 tablets/bottle, 200 tablets (10 tablets/PTP × 20)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.