Question 1

What are the indications and effects of Turoxin Tablet (Ofloxacin)?

Accepted Answer

This medication is an antibiotic effective against various bacteria, primarily used for the treatment of infections caused by various types of bacteria including Staphylococcus, Streptococcus pneumoniae, and Escherichia coli. Its main indications include complicated skin and soft tissue infections, acute and chronic otitis media, bacterial sinusitis, community-acquired pneumonia, exacerbations of chronic obstructive pulmonary disease, acute pyelonephritis and urinary tract infections, bacterial dysentery and enteritis, infections of the uterus and adnexa in women, various eye diseases, and various infections such as leprosy. However, fluoroquinolone antibiotics are recommended to be used only when other treatment options are unavailable due to the risk of serious adverse reactions. This medication is effective in treating various infections caused by the aforementioned bacteria and improves the symptoms of infection.

Question 2

What are the dosage and administration instructions for Turoxin Tablet (Ofloxacin)?

Accepted Answer

○ The usual adult dose is 300～600 mg of ofloxacin per day, taken in 2～3 divided doses.

○ For Hansen's disease, take 400～600 mg of this medicine per day in 2～3 divided doses. In principle, use it in combination with other anti-Hansen's disease medicines.

Adjust the dose as appropriate according to age and symptoms.

Question 3

What are the side effects of Turoxin Tablet (Ofloxacin)?

Accepted Answer

Tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects, exacerbation of myasthenia gravis, anaphylactic shock, anaphylactic reaction, rash, itching, erythema, edema, fever, heat sensation, vesicles, erythema, photosensitivity reaction, hematuria, acute renal failure, nephrolithiasis, interstitial nephritis, elevated BUN, elevated serum creatinine, jaundice, liver failure, elevated AST/ALT, elevated ALP, elevated γ-GTP, elevated total bilirubin, cholestatic jaundice, fulminant hepatitis, pseudomembranous colitis, hematochezia, abdominal pain, frequent diarrhea, nausea, vomiting, gastrointestinal discomfort, diarrhea, cirrhosis, loss of appetite, abdominal discomfort, dyspepsia, chest pain, thirst, taste disturbance, stomatitis, glossitis, abdominal bloating, constipation, dysphagia, gastrointestinal bleeding, oral mucosal pain, intestinal perforation, anemia, leukopenia, decreased hemoglobin, decreased hematocrit, thrombocytopenia, eosinophilia, agranulocytosis, thrombotic thrombocytopenic purpura, petechiae, purpura, prolonged prothrombin time, reversible bone marrow suppression, lymphocytopenia, neutropenia, increased ESR, insomnia, dizziness, headache, seizures, tremors, numbness, peripheral neuropathy, visual disturbances, auditory disturbances, hallucinations, drowsiness, nervousness, sleep disturbances, confusion, anxiety, depression, agitation, delusions, seizures, nightmares, paranoia, disorientation, attention deficit, memory impairment, delirium, suicidal ideation, suicide, perceptual disturbances, olfactory disturbances, balance disturbances, ataxia, aphasia, heaviness in the head, skin and mucous membrane syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, Rielle syndrome, joint pain, myalgia, muscle weakness, myositis, asthenia, elevated CPK, elevated myoglobin, rhabdomyolysis, pharyngitis, dyspnea, bronchospasm, allergic pneumonia, nosebleed, wheezing, fever, cough, abnormal chest X-ray, eosinophilia, interstitial pneumonia, cerebral thrombosis, pulmonary edema, tachycardia, hypertension, hypotension, palpitations, vasodilation, circulatory collapse, QT prolongation, ventricular tachycardia, dysuria, polyuria, urinary retention, anuria, polyuria, hematuria, storage urinary issues, pyuria, diabetes, proteinuria, alkaline urine, vaginitis, vaginal candidiasis, increased vaginal discharge, itching of the female external genitalia, menstrual irregularities, uterine cramps, female genital rash, pain, irritation, burning sensation, hypoglycemic symptoms, limb pain, malaise, fever

Question 4

What precautions should be taken when using Turoxin Tablet (Ofloxacin)?

Accepted Answer

This medication is a fluoroquinolone antibiotic and is used to treat certain bacterial infections.

Be cautious while taking this medication as serious side effects such as tendonitis or tendon rupture, peripheral neuropathy, central nervous system effects, and exacerbation of myasthenia gravis may occur.

If any of these symptoms develop, stop taking the medication immediately and consult with healthcare professionals.

Patients with myasthenia gravis should not take this medication as it may exacerbate symptoms.

This medication is not to be used in children and growing adolescents, or in women who are pregnant or breastfeeding.

Additionally, avoid taking this medication if you have a known allergy or hypersensitivity to it.

Elderly patients or those with impaired renal function require caution and dosage adjustment due to a possible increase in drug concentration.

This medication may increase sensitivity to sunlight, hence it is advisable to avoid strong sunlight or artificial UV exposure.

While on this medication, dizziness or neurological symptoms may occur, requiring caution when driving or operating machinery.

This medication may interact with other drugs, so inform healthcare professionals, especially when taking anticoagulants, diabetes medications, antacids, etc.

It is important to maintain adequate hydration to reduce the burden on the kidneys while taking this medication.

If symptoms of severe allergic reactions, skin rashes, breathing difficulties, severe abdominal pain, or hematuria occur, consult healthcare professionals immediately.

Women who are pregnant or may become pregnant should not take this medication, and breastfeeding women should also discontinue it.

The safety of this medication has not been established in children and adolescents, hence it is not used in these populations.

In case of overdose, symptoms such as drowsiness, nausea, and dizziness may occur, thus strict adherence to the prescribed dosage is essential.

This medication should be administered slowly when given intravenously, as rapid administration may cause hypotension.

Turoxin Tablet (Ofloxacin)

Summary

Ingredients

Efficacy & effects

How to take

Adult dose

Precautions

Side effects

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