Tranultrazodon Hydrochloride Capsules

Adult dosage

As an initial dose, administer Trazodone Hydrochloride 150 mg orally per day and increase by 50 mg every 3 to 4 days. Outpatients should not exceed 400 mg per day, and inpatients (with severe depression) should not exceed 600 mg per day. For the elderly, initiate with an oral dose of 100 mg per day and gradually increase, ensuring that a single dose does not exceed 100 mg, and the total daily dose does not exceed 300 mg.

This drug is not approved for use in children and adolescents under 18 years of age who have major depressive disorder or psychiatric disorders, as there may be an increased risk of suicidal thoughts and behaviors in this age group. Careful monitoring is required when administering this drug to patients with a risk of suicidal tendencies, especially among young adults aged 18 to 24. Patients and caregivers should closely monitor for any unusual behavioral changes such as suicidal thoughts, aggression, and anger. Prolonged erection may occur; if this happens, discontinue use immediately and consult a doctor. Patients allergic to this drug or its components, those with certain heart conditions, alcohol dependence, or those taking specific medications (e.g., MAO inhibitors, saquinavir) should not use this drug. Patients with heart disease, glaucoma, convulsive disorders, bipolar disorder, or liver or kidney dysfunction should use this drug with caution. This medication may cause drowsiness or decreased concentration; caution should be exercised when driving or operating hazardous machinery. Regular blood tests should be conducted to monitor white blood cell counts, and if signs of infection appear, medical attention should be sought immediately. This drug may interact with other medications, so it is essential to inform the doctor of any current medications, particularly when used in conjunction with blood pressure medications, anticoagulants, certain antidepressants, or sedatives. Pregnant women or those who may become pregnant should carefully consider the risks and benefits of using this drug, and breastfeeding women should avoid use or discontinue breastfeeding. When administering this drug to the elderly, dose adjustments should be made considering declining physical functions. Abruptly discontinuing this medication may lead to withdrawal symptoms such as nausea, headache, anxiety, and sleep disturbances, so it should be tapered off under a doctor’s guidance. Severe adverse reactions may occur in cases of overdose, and immediate medical attention should be sought. Finally, this drug should be kept out of the reach of children and stored in its original container to maintain quality.

• Motor paralysis
• severe muscle rigidity
• dysphagia
• tachycardia
• blood pressure changes
• sweating
• fever
• leukocytosis
• elevated serum creatine kinase
• myoglobinuria

This drug should be stored in a tightly sealed container to prevent air from entering, and it is safe to store it at room temperature between 1 and 30 degrees Celsius. This will help maintain the drug's effectiveness and prevent degradation.

Appearance

Hard capsules with a green upper part and a white lower part containing a white to light yellow powder

Package unit

500 capsules/bottle