Samion Tablet 10 Milligrams (Nisergoline)

Adult dose

* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally three times daily before meals. Adjust the dose as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before meals. If the desired effect is not achieved at this dose, it may be increased to 60 mg. The dose may be reduced after symptoms improve. For patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL), administer a reduced dose.

This medication should not be used by individuals allergic to this drug or ergot alkaloids. It must not be administered to patients with acute myocardial infarction or acute bleeding. It should also not be used in patients taking sympathomimetic drugs or those with a very low heart rate (less than 50 beats per minute). Do not administer this medication to patients who have not completed hemostasis after intracranial bleeding or those with orthostatic dysregulation. Patients with mild bradycardia or impaired kidney function should use this drug cautiously. While taking this medication, gastrointestinal symptoms such as decreased appetite, diarrhea, constipation, nausea, vomiting, abdominal pain, and dry mouth may rarely occur. Liver function abnormalities may lead to increased liver enzyme levels. Cardiovascular side effects such as dizziness, orthostatic hypotension, increased or decreased blood pressure, and elevated serum uric acid levels may occur. Neurological symptoms such as drowsiness, lethargy, headache, tinnitus, fatigue, and insomnia may also rarely arise. Allergic reactions like rash, urticaria, itching, facial flushing, and warmth may occur, so caution is advised. When used with other antihypertensive agents, blood pressure may drop too low, necessitating regular monitoring of blood pressure. It can affect uric acid metabolism, so special caution is required for patients with a history of gout. Post-treatment, drowsiness or decreased concentration may occur, so caution should be taken when driving or operating machinery. This medication is metabolized in the liver, so interactions with other drugs related to liver metabolism may occur. Women who are pregnant or may become pregnant should consult their doctor regarding use, as it may affect the fetus. In cases of breastfeeding, this medication may be excreted in breast milk, so avoidance of use or discontinuation of breastfeeding is advisable. Elderly individuals may have reduced bodily functions, so dosage adjustments should be made with care. Safety for use in children has not been confirmed, so it is preferable not to use it in pediatric patients. In case of overdose, blood pressure may temporarily decrease, so any unusual symptoms should be immediately reported to medical personnel. This medication should be kept out of the reach of children and stored sealed in its original container to maintain its quality.

• Loss of appetite
• diarrhea
• constipation
• nausea
• vomiting
• diffuse upper abdominal pain or cramps
• thirst
• ALT elevation
• AST elevation
• dizziness

This medication should be stored in an airtight container that protects it from light, and it is best stored at room temperature between 1 and 30 degrees Celsius. This will help maintain its efficacy and prevent deterioration.

Appearance

This medication is a white, round tablet.

Package unit

For oral use (30 tablets) - 30 tablets/bottle, For oral use (100 tablets) - 100 tablets/bottle, For oral use (500 tablets) - 500 tablets/bottle