Medication info
Myeongin Benztropine Mesylate Tablet 2 mg

Myeongin Benztropine Mesylate Tablet 2 mg

Prescription medicationTablet
Ingredient · strength
Benztropine Mesylate›2mg / 1 tablet
Manufacturer / importer
Myeongin Pharmaceutical Co., Ltd.
Appearance
White round tablets
Packaging
1000 tablets/bottle
Approval status
Active

MFDS item code 198500629 · Notified 1985.04.17 · Insurance code 651900610

Summary

Main use
Treatment of antipsychotic-induced parkinsonism and idiopathic and other forms of parkinsonism
Who uses it
Adults
Adult dosage
(Oral: tablets) Adults: The initial dose is 0.5-1㎎ of benztropine mesylate daily, administered orally. Thereafter, gradually increase the dose by 0.5㎎ daily at intervals of 5-6 days until the maintenance dose is reached. Determine the maintenance dose based on improvement in symptoms and the occurrence of adverse effects, and do not exceed 6㎎ daily. Adjust the dose as appropriate according to age and symptoms. (Injection) ○ Adults 1. The initial dose is 0.5-1㎎ of benztropine mesylate daily, administered intramuscularly or intravenously. Thereafter, gradually increase the dose by 0.5㎎ daily at intervals of 5-6 days until the maintenance dose is reached. Determine the maintenance dose based on improvement in symptoms and the occurrence of adverse effects, and do not exceed 6㎎ daily. 2. In an emergency, inject 1-2㎎ of this drug to relieve symptoms, then administer 1-2㎎ orally twice daily to prevent recurrence. The injection should be administered intramuscularly or intravenously in emergencies or when oral administration is not possible. Adjust the dose as appropriate according to age and symptoms.

Ingredients

Manufacturer
Myeongin Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of antipsychotic-induced parkinsonism and idiopathic and other forms of parkinsonism

  • Idiopathic Parkinson's disease
  • other Parkinson's disease
  • post-encephalitic Parkinson's disease
  • atherosclerotic Parkinson's disease
  • Parkinson's disease induced by antipsychotic drug administration.
View approved original text

This medicine is used for idiopathic Parkinson's disease, other types of Parkinson's disease caused by post-encephalitis or atherosclerosis, and Parkinson's disease resulting from the administration of antipsychotic medications.

Dosage and Administration

Adult dosage

(Oral: tablets) Adults: The initial dose is 0.5-1㎎ of benztropine mesylate daily, administered orally. Thereafter, gradually increase the dose by 0.5㎎ daily at intervals of 5-6 days until the maintenance dose is reached. Determine the maintenance dose based on improvement in symptoms and the occurrence of adverse effects, and do not exceed 6㎎ daily. Adjust the dose as appropriate according to age and symptoms. (Injection) ○ Adults 1. The initial dose is 0.5-1㎎ of benztropine mesylate daily, administered intramuscularly or intravenously. Thereafter, gradually increase the dose by 0.5㎎ daily at intervals of 5-6 days until the maintenance dose is reached. Determine the maintenance dose based on improvement in symptoms and the occurrence of adverse effects, and do not exceed 6㎎ daily. 2. In an emergency, inject 1-2㎎ of this drug to relieve symptoms, then administer 1-2㎎ orally twice daily to prevent recurrence. The injection should be administered intramuscularly or intravenously in emergencies or when oral administration is not possible. Adjust the dose as appropriate according to age and symptoms.

Precautions

This drug should not be used in patients with glaucoma, those who are hypersensitive to this drug, patients with myasthenia gravis, and infants under 3 years of age. Additionally, as this drug contains lactose, it should not be administered to patients with genetic disorders such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption. Patients with urinary obstructive diseases such as benign prostatic hyperplasia, those with arrhythmias or tachycardia, individuals with impaired liver or kidney function, elderly persons, children over 3 years old, and those in hot environments should use this drug cautiously. When taking this medication, one should be aware that symptoms such as mental confusion, hallucinations, altered consciousness, anxiety, and depression may occur. In the gastrointestinal system, symptoms such as dry mouth, nausea, vomiting, and constipation may arise, while in the urinary system, urinary difficulty or urinary retention may occur. Additionally, if skin rash or hypersensitivity reactions appear, the medication should be discontinued, and visual disturbances may occur. When starting the medication, the dosage should be gradually increased from a small amount, and this should also be done cautiously when switching from another drug to this one. It is advisable to have regular eye examinations and intraocular pressure checks during treatment. Unlike certain other antiparkinsonian agents, this medication may not relieve some involuntary movement symptoms and may even worsen them. While taking this medication, attention and reflexes may be impaired, so one should avoid driving or operating dangerous machinery. Additionally, the effect may be enhanced when taken with phenothiazine medications, tricyclic antidepressants, MAO inhibitors, and reserpine derivatives, so caution is required. Severe intestinal paralysis symptoms may occur when taken with anticholinergic drugs, and if such symptoms arise, the medication should be discontinued. It is safest for women who are pregnant or may become pregnant, as well as for nursing mothers, to avoid taking this medication.

Side effects

  • Ataxia
  • delirium
  • hallucinations
  • consciousness disturbances
  • delirium
  • neural hyperactivity
  • agitation
  • anxiety
  • depression
  • lethargy
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  • sensory abnormalities in the extremities
  • thirst
  • nausea
  • vomiting
  • constipation
  • dysuria
  • urinary retention
  • rash
  • control disorders

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to light, so it should be stored in a container that blocks light. Additionally, it should be stored in a tightly sealed container to maintain the drug's efficacy and prevent degradation.

Appearance and packaging

Appearance

White round tablets

Package unit

1000 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.