This product's status changed to Approval withdrawn on 2025.07.21. It may no longer be sold, so consult a doctor or pharmacist before taking it.
Summary
- Main use
- Improvement of hypoproteinemia and malnutrition
- Who receives it
- Adults · Children
- Adult administration
- For adults, administer via intravenous drip at a maximum dosage of 1-1.5 g of total amino acids per kg of body weight per day. The infusion rate should ideally contain approximately 10 g of total amino acids over a 60-minute infusion period, and the principle is to administer 80-130 drops per minute. The maximum daily dose is 100 g of D-Sorbitol.
- Child administration
- In pediatric patients, the dosage and infusion rate should be adjusted accordingly.
Ingredients
- L-Lysine Hydrochloride350mg / 100mL
- L-Isoleucine220mg / 100mL
- L-Leucine330mg / 100mL
- L-Methionine200mg / 100mL
- L-Phenylalanine220mg / 100mL
- L-Threonine200mg / 100mL
- L-Tryptophan90mg / 100mL
- L-Valine280mg / 100mL
- Glycine380mg / 100mL
- L-Alanine380mg / 100mL
- L-Arginine500mg / 100mL
- L-Proline370mg / 100mL
- L-Serine370mg / 100mL
- L-Tyrosine50mg / 100mL
- L-Histidine Hydrochloride Hydrate138mg / 100mL
- L-Ornithine Hydrochloride126mg / 100mL
- L-Aspartic Acid570mg / 100mL
- L-Glutamic Acid350mg / 100mL
- Xylitol5000mg / 100mL
- D-Sorbitol5000mg / 100mL
- Manufacturer
- 제일약품(주)
Efficacy & effects
Improvement of hypoproteinemia and malnutrition
- Hypoproteinemia
- malnutrition
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Amino acid supplementation is needed in cases of hypoproteinemia, malnutrition, and situations such as before and after surgery. In these conditions, protein synthesis in the body may decrease or be lost, so appropriate amino acid supplementation is required to improve nutritional status and assist in recovery. Amino acid supplementation is used to improve hypoproteinemia and enhance overall nutritional status.
How it is given
Adult administration
For adults, administer via intravenous drip at a maximum dosage of 1-1.5 g of total amino acids per kg of body weight per day. The infusion rate should ideally contain approximately 10 g of total amino acids over a 60-minute infusion period, and the principle is to administer 80-130 drops per minute. The maximum daily dose is 100 g of D-Sorbitol.
Child administration
In pediatric patients, the dosage and infusion rate should be adjusted accordingly.
Precautions
This medication must be used according to a doctor's instructions and should not be taken arbitrarily based on personal judgment. It should not be administered to patients at risk of hepatic coma or with severe liver dysfunction, patients with severe kidney impairment, and patients with certain metabolic disorders. Patients with severe heart failure or pulmonary edema, those with very little or no urine output, and patients with hypernatremia or hyperchloremia should also avoid using this medication. If certain components are included, it should be avoided in patients with lactic acidosis, methanol poisoning, hereditary fructose intolerance, heart block, or severe myasthenia gravis. This medication should be used with caution in patients with severe acidosis, congestive heart failure, edema due to sodium retention, hyperkalemia, and those with impaired liver or kidney function should be observed closely. Some components in this medication may cause allergic reactions, particularly anaphylaxis or asthma attacks, so asthmatic patients should be especially cautious. Various side effects may appear during administration, such as rash, nausea, vomiting, palpitations, increased blood pressure, so any unusual symptoms should be reported to medical personnel immediately. Rapid administration of large amounts may lead to acidosis, so the rate and amount of administration must be strictly managed. Patients with kidney disease, lung disease, or heart disease should avoid excessive fluid administration, and diabetic patients should frequently monitor blood glucose levels. There may be interactions with other medications, so if you are taking other medications, you must inform medical personnel. Pregnant women should use this medication cautiously only when absolutely necessary, as its safety has not been fully established. When administered to children or elderly patients, dosage and infusion rates should be adjusted to reduce the risk of side effects. This medication contains electrolytes, so care should be taken with electrolyte balance, and it should be infused slowly into the vein during administration. To reduce the risk of infection during administration, maintain strict aseptic conditions and do not use if the solution is discolored or abnormal. If certain components are included, the rate and amount of administration must be strictly limited to prevent kidney or liver damage. Lastly, this medication is not safe to use in patients with a history of myocardial infarction.
Side effects and when to seek care immediately
Serious side effects
Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, rash with high fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, jaundice (yellowing of the skin or eyes), profound drowsiness, sudden and severe headache, thunderclap headache, seizures, altered consciousness, vision changes, paralysis, significantly decreased urine output.
Mild side effects
- Rash
- nausea
- vomiting
- chest discomfort
- palpitations
- tachycardia
- increased blood pressure
- acidosis
- warmth
- vascular pain
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- chills
- fever
- headache
- shock
- bronchial spasm
- urinary tract spasm
- peripheral vessel dilation
- metabolic acidosis
- hypophosphatemia
- alkalosis
- hyperglycemia
- diabetes
- osmotic diuresis
- and dehydration
- rebound hypoglycemia
- increased liver enzymes
- vitamin deficiencies and excesses
- electrolyte imbalances
- pediatric hyperammonemia
- increased BUN
- serum amino acids.
Not everyone experiences these, and they can vary from person to person.
Storage
This medication should be stored in a sealed container to prevent exposure to air and is best stored at room temperature between 1 and 30 degrees Celsius. Storing it this way will help maintain the medication's efficacy and allow for safe use.
Appearance and packaging
Appearance
The product is a colorless or pale yellow transparent aqueous injection.
Package unit
For internal use - 500 milliliters per package
Questions about this medicine
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For anything that needs medical judgment, consult a doctor or pharmacist.