Erbin Injection (Methyl Ergometrine Maleate)

Adult dosage

(Oral: tablets) Adults: The usual dose is 0.125-0.25mg of methylergometrine maleate per dose, taken orally 2-4 times daily. The dose may be adjusted as appropriate depending on age and symptoms. (Injection) Adults: The usual dose is 0.1-0.2mg of methylergometrine maleate per dose by intravenous injection, or 0.2mg per dose by subcutaneous or intramuscular injection. The dose may be adjusted as appropriate depending on age and symptoms.

This drug is in the form of an injection, so caution should be taken when opening the glass container to avoid the risk of glass fragments contamination. Special care is needed when used by children or the elderly. It should not be used in pregnant women or women who might be pregnant, women in labor, patients with eclampsia, or patients undergoing labor induction. Patients with hypertension or pregnancy-related hypertension, those allergic to this drug or ergot alkaloids, and patients with severe heart disease or pulmonary vascular disease should also avoid use. Patients with heart disease or weakened liver and kidney functions should be especially cautious when using this drug. During usage, gastrointestinal symptoms such as nausea, vomiting, abdominal pain, diarrhea, or circulatory symptoms such as changes in blood pressure, chest pain, and heart rhythm irregularities may occur. Neurological symptoms such as headache, drowsiness, dizziness, and hallucination have also been reported. If an allergic reaction manifests as a rash or anaphylaxis, administration should be discontinued immediately. This drug can induce uterine contractions, making it dangerous for pregnant women, and it can also be transmitted through breast milk, potentially affecting infants, so breastfeeding mothers should use it only in special cases. In case of overdose, severe symptoms such as vomiting, blood pressure abnormalities, seizures, and coma may appear, so immediate medical attention should be sought. When used with this drug, there may be potential interactions with other medications, particularly those that cause vascular constriction, so caution should be exercised in combination. Injection sites should be carefully chosen to avoid nerve damage, and intravascular injections or injections around arteries should be avoided. The effects on driving or operating machinery are unknown, but caution is advised during the early stages of treatment.

Nausea, vomiting, abdominal pain, diarrhea, increased blood pressure, decreased blood pressure, chest pain, chest tightness, tachycardia, bradycardia, palpitations, peripheral vascular spasm, myocardial infarction, angina pectoris, coronary artery spasm, atrioventricular block, headache, drowsiness, dizziness, thirst, tinnitus, agitation, convulsions, cerebral vascular accident, hallucinations, rash, anaphylactic reaction, placental abruption, sweating, abdominal pain due to uterine contractions, shock, cyanosis, respiratory distress, collapse, anxiety, acute gastritis, chills, pallor, limb paralysis, arthralgia, pain, respiratory dysfunction, coma

This drug is sensitive to light, so it should be stored in a container that does not allow light to enter, and to maintain freshness, it should be stored at refrigerated temperatures between 2 to 8 degrees Celsius. Therefore, it is important to store the drug safely in a cool place away from direct sunlight until it is used.

Appearance

Colorless and transparent injection solution contained in a brown ampoule

Package unit

Domestic use: 1mL/ampoule x 50, for export: 1mL/ampoule x 10, 50, 100