Key information summary
Efficacy & effects
This medication is used for the prevention and treatment of vitamin C deficiency in cases of acute illness or when oral administration is difficult. It helps improve vitamin C deficiency diseases such as scurvy, and is beneficial in situations where the demand for vitamin C is increased, such as in pregnant women, nursing mothers, and during severe physical labor. It is also effective in promoting bone matrix formation and bone union during fractures, as well as alleviating skin issues like melasma, freckles, post-inflammatory pigmentation, and photosensitive dermatitis. Overall, this product is useful for improving vitamin C deficiency and related metabolic disorders.
Dosage
Administer as ascorbic acid, 50-1,000 mg once to several times daily via subcutaneous, intramuscular, or intravenous injection. Adjust dosage according to age and symptoms.
Precautions
Be very cautious when opening the injection container, as glass fragments may enter. Special care is needed when it is used by children or the elderly. This medication contains sodium bisulfite, which may cause severe allergic reactions or asthma attacks in individuals allergic to sulfites, so it should be used with caution. Patients with asthma should be particularly careful. This medication should not be used in certain patients. For example, it should be avoided in individuals allergic to this medication or its components, patients with hyperoxaluria or Mediterranean anemia, patients with gout or cystinuria, patients with G6PD deficiency, and those with kidney calculi consisting of oxalate. When using this medication, side effects such as nausea, vomiting, diarrhea, stomach pain, abdominal cramps, fatigue, flushing, headaches, and insomnia may occur. Administering more than 1 gram per day can acidify the urine, increasing the risk of diarrhea or kidney stones. Administering more than 600 milligrams per day may cause diuretic effects, and hemolysis may occur in G6PD deficient patients. Excessive dosing can lead to precipitation of oxalate or urate in the urinary tract, so caution is required. This medication is generally taken orally, but injections are to be used only in acute conditions or when oral intake is not possible, and transitioning to oral administration is preferred when possible. This medication may interact with other drugs. Salicylates can interfere with its absorption, and combinations with aspirin, nicotine, alcohol, certain appetite suppressants, iron preparations, specific anticonvulsants, oral contraceptives, and tetracycline antibiotics may reduce its efficacy, so concomitant use should be avoided. Additionally, high-dose administration may reduce the effects of some anticoagulants and may interact with certain psychiatric medications. During pregnancy, the effects on the fetus are not clear, so this medication should only be administered when the benefits exceed the risks, and high-dose administration exceeding 1 gram should be avoided. During breastfeeding, this medication can pass into breast milk, but it is reportedly not harmful to the infant at normal doses. This medication can influence the results of some clinical tests, leading to false results in urine glucose tests, hematuria tests, and stool occult blood tests. Overdose can cause diarrhea or kidney stones, and doses exceeding 600 milligrams per day may cause diuretic effects, so if symptoms occur, it is important to discontinue use immediately and seek appropriate treatment. When administered by injection, temporary pain may occur at the injection site, and the site should be changed or kept away from nerve areas, while minimizing the amount injected. If there is pain or blood reflux during injection, the needle should be withdrawn immediately, and intravenous injections should be given slowly to reduce dizziness or vascular pain. Finally, this medication should be stored out of reach of children, in a dry place away from direct sunlight. If the medication is taken out of its original container and stored in another, it may lead to misuse or deterioration of quality, so it should be kept in its original container with the lid tightly closed.
Side effects
Sulfite anaphylaxis (severe allergic reaction), asthma attacks (respiratory issues), hemolysis (possible in G6PD deficiency patients), increased risk of kidney stones, diarrhea and kidney stone risk (when administered more than 1 gram per day)