Cheil Pharmaceutical Ascorbic Acid Injection 5%

Key information summary

Efficacy & effects

This medication is used for the prevention and treatment of acute vitamin C deficiency, known as scurvy. It is also necessary to take in situations where the demand for vitamin C increases, such as for pregnant or breastfeeding women, or for those engaging in heavy physical labor. It is helpful for symptoms related to capillary bleeding, such as nosebleeds, gum bleeding, and hematuria. It is effective for metabolic disorders of vitamin C that can occur with certain drug administration. It aids recovery by promoting bone matrix formation and bone union in fractures. It is also used to improve skin-related symptoms such as melasma, freckles, post-inflammatory hyperpigmentation, and photosensitive dermatitis.

Dosage

As ascorbic acid, administer 50 to 1,000 mg daily, either once or divided into several doses via subcutaneous, intramuscular, or intravenous injection. Adjust dosage appropriately based on age and symptoms.

Precautions

This medication is in ampule form, so be careful when opening the container as glass fragments may mix in. Extra caution should be exercised when used by children or the elderly. This medication contains an excipient called sodium bisulfite, which can cause allergic reactions. Asthma patients should be especially careful as severe cases may lead to life-threatening asthma attacks. This medication should not be used in certain patients, such as those allergic to this medication or its components, patients with hyperoxaluria or Mediterranean anemia, patients with gout or cystinuria, and individuals with G6PD deficiency. Caution is also advised for patients with kidney stones. During use, symptoms such as nausea, vomiting, diarrhea, abdominal pain, headache, fatigue, and flushing may occur. Administering more than 1 gram per day can increase the risk of diarrhea or kidney stones, and doses exceeding 600 milligrams may cause diuretic effects. Patients with G6PD deficiency should be careful as hemolysis may occur. Overdosing on this medication can lead to kidney stones in the urine and cause diarrhea, so it is essential to adhere to the prescribed dosage. If oral administration is possible, it is recommended to switch from injection to oral intake. Interactions may occur when used with other medications, so caution should be exercised especially when taking with salicylates, aspirin, iron supplements, some anticonvulsants, and oral contraceptives. During pregnancy, it is advisable not to take more than 1 gram of this medication, and since the effects on the fetus are unclear, it should only be used cautiously when necessary. While breastfeeding, this medication may pass into breast milk, but at standard dosages, there is no significant risk to the baby. This medication can affect test results, so care is needed for the interpretation of urine and stool tests. There may be temporary pain at the injection site, and it is advisable to rotate injection sites. For intravenous injections, slow administration can help reduce dizziness or vascular pain.

Side effects

Severe allergic reactions such as anaphylaxis from sulfites Asthma attacks Hemolysis in G6PD deficiency patients Increased risk of calcium oxalate stones in the kidneys

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