Yuyu Creed Tablet (Ticlopidine Hydrochloride)

Adult dose

Treatment of thrombus and embolism during vascular surgery and extracorporeal circulation, and improvement of blood flow disorders: As Ticlopidine Hydrochloride, the usual adult dosage is 200 to 300 mg per day, divided into 2 to 3 doses after meals. Improvement of ischemic symptoms such as ulcers, pain, and coldness due to chronic arterial occlusive disease: The usual adult dosage is 300 to 600 mg per day, divided into 2 to 3 doses after meals. Treatment of thrombus and embolism due to ischemic cerebrovascular disorders: The usual dose is 500 mg per day, divided into 2 doses after meals.

This medication is a drug that inhibits the function of platelets in the blood to prevent thrombus formation. A serious blood disorder reaction with a rapid decrease in platelet count may occur within the first 2 months of taking this medication, so regular blood tests and liver function tests should be conducted. It is particularly important to check blood status every two weeks during the first three months of administration, and if any abnormal symptoms appear, the medication should be stopped immediately and a doctor consulted. Patients at high risk of bleeding, patients with severely impaired liver function, or those with a history of blood disorders should not take this medication. Women who are menstruating or those taking anticoagulants, antiplatelet agents, etc., should use this medication with caution, and patients scheduled for surgery or elderly patients should also be careful. During use, abnormal symptoms such as bleeding, fever, vomiting, skin rash, jaundice, etc., may appear, so patients should inform the medical staff immediately if such symptoms occur. Additionally, because this medication is metabolized in the liver, patients with impaired liver function should confirm their liver status before administration, and if symptoms of hepatitis or jaundice appear, the medication should be discontinued. When taken with other anticoagulants, non-steroidal anti-inflammatory drugs, aspirin, etc., the risk of bleeding increases, so great caution should be exercised when using them together. It is preferable not to take this medication during pregnancy or breastfeeding, and safety in children has not been established, so use is not recommended. In case of overdose, the risk of bleeding may increase, so the dosage must be strictly adhered to, and if overdose is suspected, emergency treatment should be sought immediately.

Serious side effects

Thrombotic thrombocytopenic purpura (thrombocytopenia, hemolytic anemia, mental and neurological symptoms, fever, renal dysfunction), agranulocytosis (fever, pharyngitis, malaise), severe neutropenia, myelodysplastic syndrome, pancytopenia, thrombocytopenia, hemolytic anemia, tendency to bleed (intracranial bleeding, gastrointestinal bleeding, gum bleeding, subcutaneous bleeding, hematuria), leukopenia, leukemia, thrombocytosis, reticulocytosis, elevated liver enzymes, cholestasis and cytolytic liver

Mild side effects

• Diarrhea
• nausea
• vomiting
• loss of appetite
• gastric discomfort
• stomatitis
• abdominal pain
• peptic ulcer
• dyspepsia
• taste disturbances

This medication may be sensitive to air or light, so it should be stored in a tightly closed container. Also, it is advisable to store it at room temperature, avoiding excessively hot or cold places.

Appearance

White round tablets, clinical trial use: yellow round film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle