Boryung Duricef Capsule 500 mg (Cefadroxil Hydrate)

Adult dose

1) For urinary tract infections: For uncomplicated lower urinary tract infections (such as cystitis), administer 1-2g (of active ingredient) in 1-2 divided doses daily. For other urinary tract infections, administer 2g (of active ingredient) in two divided doses daily. 2) For skin and soft tissue infections: Administer 1g (of active ingredient) in 1-2 divided doses daily. 3) For pharyngitis and tonsillitis: For pharyngitis and tonsillitis caused by beta-hemolytic streptococcus, administer 1g (of active ingredient) daily.

Child dose

1) For urinary tract infections and skin and soft tissue infections: Administer 30mg/kg (of active ingredient) in two divided doses daily. 2) For pharyngitis and tonsillitis: Administer 30mg/kg (of active ingredient) in 1-2 divided doses daily.

This drug should not be administered to certain patients. For example, patients who have experienced shock due to this drug, those allergic to cephalosporin antibiotics, patients with infectious mononucleosis, and those with genetic issues preventing lactose digestion should not use this drug. Additionally, some patients should use this drug with caution. Patients with a history of allergic reactions, those allergic to penicillin antibiotics, individuals with a family history of asthma or skin allergies, patients with severely impaired kidney function, those who have difficulties with oral intake, patients with a history of gastrointestinal disorders, and those allergic to the pigments contained in this drug should be cautious when using this medication. This drug can occasionally cause serious side effects. For instance, hypersensitivity reactions such as shock, rash, urticaria, facial swelling, itching, fever, and anaphylaxis may occur. Changes in blood cell counts, liver dysfunction, deterioration of kidney function, severe colitis, respiratory issues, stomatitis, dizziness, drowsiness, headaches, skin diseases (Stevens-Johnson syndrome) can also arise, so if abnormal symptoms occur, use should be stopped immediately and medical attention sought. When using this drug, it is advisable to check the susceptibility of the infecting organism to prevent the emergence of resistant strains and to administer it for only the minimal necessary duration. Additionally, patient history is crucial to prevent allergic reactions, and if hypersensitivity occurs, drug administration should be stopped immediately and appropriate treatment provided. During prolonged use, regular checks of blood, kidney, and liver functions should be conducted to ensure there are no abnormalities. In patients with reduced kidney function, dosage adjustments may be necessary, and if seizures occur, the drug should be discontinued and anticonvulsants may be administered if needed. This drug may increase the risk of kidney dysfunction when used with other medications that can affect kidney function. Furthermore, using it with probenecid may raise its concentration in the body. Women who are pregnant or may become pregnant should use this drug only when the benefits outweigh the risks, as its safety has not been established. Nursing mothers should also use it with caution. Elderly patients may experience increased susceptibility to adverse reactions due to weakened bodily functions, and they may have a higher tendency for bleeding caused by vitamin K deficiency; thus, dosage and intervals should be carefully adjusted. This drug may affect the results of certain clinical tests, so care should be taken during testing, and symptoms of light sensitivity have been reported rarely.

Serious side effects

• Shock
• urticaria
• tightness in the chest
• difficulty breathing
• cold sweat
• pallor
• anaphylaxis
• severe colitis (with bloody stools)
• respiratory distress
• severe edema

Mild side effects

• Rash
• urticaria
• erythema
• facial swelling
• angioedema
• mucosal blistering
• itching
• fever
• thrombocytopenia
• agranulocytosis

This drug should be stored in a tightly closed container to protect it from light, air, and moisture. This helps maintain the drug's effectiveness and prevents degradation.

Appearance

Capsules filled with a white to yellowish powder, with the upper part being dark red and the lower part being milky white.

Package unit

30 capsules/bottle, 100 capsules/bottle, 500 capsules/bottle