Daewoong Primidone Tablet

Adult dose

1. Adults: During the first 3 days of treatment, administer 250㎎ of primidone orally once daily at bedtime. Depending on symptoms and the severity of seizures, increase the dose by 250㎎ at 3-day intervals, gradually increasing to 1.5g daily. Once the maintenance dose is reached, divide it into 2-3 doses. If necessary, the dose may be increased to 2g daily, but do not exceed this amount. Adjust the dose as appropriate according to age and symptoms.

Child dose

During the first 3-4 days of treatment with this medicine, administer 125㎎ once daily at bedtime. Increase the dose by 125㎎ at 3-day intervals and, once the maintenance dose is reached, divide it into 2-3 doses. Ages 6-15: 0.75-1g daily Ages 3-5: 0.5-0.75g daily Ages 2 and under: 0.25-0.5g daily

This medication may increase the risk of suicidal thoughts or behaviors during treatment; therefore, patients and caregivers should carefully monitor for mood changes or symptoms of depression. It is used for the treatment of epilepsy or other diseases, and it should be used with caution in patients with liver or kidney function issues, cardiovascular diseases, hypothyroidism, respiratory function impairment, pregnant or lactating women, and the elderly. This medication should not be administered to patients with acute intermittent porphyria or those hypersensitive to certain drugs, as well as to patients with central nervous system depressants or alcohol addiction. Rarely, serious skin reactions, blood disorders, neurological disorders, gastrointestinal problems, or heart issues may occur; if any abnormal symptoms appear, immediate consultation with healthcare personnel is necessary. Abruptly discontinuing this medication may cause seizures, so it is important to taper off the dosage gradually. Drowsiness or reduced concentration may occur while taking this medication, so driving or operating dangerous machinery should be avoided. Drug interactions may occur if taken with other medications or alcohol; therefore, it is essential to inform healthcare personnel of any concurrent medications. During pregnancy, there is a risk of fetal malformations or bleeding; hence, the administration of this medication should be made after careful consideration of the benefits and risks to both the mother and fetus, and vitamin K supplementation may be required before and after delivery. During lactation, this medication can be transmitted through breast milk, which may cause drowsiness in infants; therefore, breastfeeding should be discontinued or discussed with a doctor. In cases of overdose, symptoms of central nervous system depression may appear, requiring immediate emergency treatment, and as there is no specific antidote, gastric lavage and symptomatic treatment are necessary. It is important to regularly check liver function, kidney function, blood tests, etc., to monitor health status while using this medication.

suicidal impulses, suicidal behavior, depression, abnormal changes in mood and behavior, mucocutaneous syndrome, aplastic anemia, eosinophilia with systemic symptoms in drug response, toxic epidermal necrolysis, exfoliative dermatitis, systemic lupus erythematosus, dependence, withdrawal symptoms, anxiety, insomnia, seizures, nausea, hallucinations, delusions, agitation, confusion, drowsiness, decreased attention, decreased concentration, impaired reflex motor ability, dizziness, ataxia, headache, lethargy, fatigue, mood disorders, speech disturbances, confusion, nervousness, memory impairment, personality changes, altered mental status, psychotic reactions, personality changes, diplopia, nystagmus, nausea, vomiting, loss of appetite, neutropenia, eosinophilia, erythropoietic dysfunction, megaloblastic anemia, leukopenia, thrombocytopenia, bradycardia, hypotension, shock, arrhythmia, measles-like rash, papular lesions, abnormal thyroid function test results, hematoporphyrinuria, excessive salivation, abnormal liver function test results, proteinuria, rickets, osteomalacia, failure of alveolar bone formation, arthralgia, Dupuytren's contracture, erectile dysfunction, irritability, abnormal serum immunoglobulin, nystagmus, speech disturbances, ataxia, ophthalmoplegia, loss of consciousness, respiratory depression, comatose state

This medication should be stored in a tightly sealed container to protect it from exposure to air and light, which helps maintain its efficacy and prevents degradation.

Appearance

This medicine is a white tablet.

Package unit

30 tablets/bottle